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The map label for this gene is sufA

Identifier: 218695245

GI number: 218695245

Start: 1912648

End: 1913016

Strand: Reverse

Name: sufA

Synonym: EC55989_1851

Alternate gene names: 218695245

Gene position: 1913016-1912648 (Counterclockwise)

Preceding gene: 218695246

Following gene: 218695244

Centisome position: 37.11

GC content: 53.66

Gene sequence:

>369_bases
ATGGACATGCATTCAGGAACCTTTAACCCACAGGATTTCGCCTGGCAAGGCTTAACGCTGACACCCGCAGCGGCGATACA
CATCCGTGAGCTGGTGGCAAAGCAGCCGGGTATGGTCGGCGTGCGCTTAGGCGTGAAGCAAACGGGCTGCGCGGGCTTTG
GCTATGTGCTCGACAGTGTTAGCGAGCCGGACAAAGACGATCTGCTGTTTGAACACGACGGCGCGAAGCTGTTTGTCCCG
CTGCAAGCGATGCCGTTTATTGATGGCACGGAAGTCGATTTCGTTCGTGAAGGACTTAATCAGATATTCAAATTTCACAA
CCCTAAAGCCCAGAATGAATGTGGCTGTGGCGAAAGCTTTGGGGTATAG

Upstream 100 bases:

>100_bases
CATGTTTTACGGTAAAGCCCCTGCGTTTGCTGGGTTGAACTGATAATCATTATCACTAACATGCTGTTATACGCTGAAAG
CGATGAAGTGAGGTAAATAG

Downstream 100 bases:

>100_bases
GCGGTACTATGTCTCGTAATACTGAAGCAACTGACGATGTCAAAACCTGGACCGGCGGCCCGCTGAATTATAAAGAAGGA
TTCTTCACCCAGTTAGCCAC

Product: iron-sulfur cluster assembly scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV

Sequences:

>Translated_122_residues
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV
>Mature_122_residues
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=38.6792452830189, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI160420328, Length=98, Percent_Identity=37.7551020408163, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787974, Length=122, Percent_Identity=100, Blast_Score=254, Evalue=1e-69,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=47.6190476190476, Blast_Score=111, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=40, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=46.2264150943396, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUFA_ECOLI (P77667)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D64926
- RefSeq:   AP_002304.1
- RefSeq:   NP_416199.1
- PDB:   2D2A
- PDBsum:   2D2A
- ProteinModelPortal:   P77667
- SMR:   P77667
- STRING:   P77667
- EnsemblBacteria:   EBESCT00000002601
- EnsemblBacteria:   EBESCT00000017067
- GeneID:   949014
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1674
- KEGG:   eco:b1684
- EchoBASE:   EB1352
- EcoGene:   EG11378
- eggNOG:   COG0316
- GeneTree:   EBGT00050000009093
- HOGENOM:   HBG730174
- OMA:   HACGCGE
- ProtClustDB:   PRK09504
- BioCyc:   EcoCyc:EG11378-MONOMER
- Genevestigator:   P77667
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011298
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049
- TIGRFAMs:   TIGR01997

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13300; Mature: 13300

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSV
CCCCCCCCCCCCCEECCCEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCC
SEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GV
CC
>Mature Secondary Structure
MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSV
CCCCCCCCCCCCCEECCCEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCC
SEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040