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The map label for this gene is uidR

Identifier: 218695180

GI number: 218695180

Start: 1845194

End: 1845784

Strand: Reverse

Name: uidR

Synonym: EC55989_1784

Alternate gene names: 218695180

Gene position: 1845784-1845194 (Counterclockwise)

Preceding gene: 218695181

Following gene: 218695179

Centisome position: 35.81

GC content: 50.76

Gene sequence:

>591_bases
ATGATGGATAACATGCAGACTGAAGCACAACCGACACGGACCCGGATCCTCAATGCTGCCAGAGAGATTTTTTCAGAAAA
TGGATTTCACAGTGCCTCGATGAAAGCCATCTGTAAATCCTGCGCCATCAGTCCCGGGACGCTCTATCACCATTTCATCT
CCAAAGAAGCCTTGATTCAGGCGATTATCTTACAGGACCAGGAGAGGGCGCTGGCCCGTTTCCGGGAACCGATTGAAGGG
ATTCATTTTGTTGACTATATGGTCGAGTCTATTGTCTCTCTCACCCATGAAGCCTTTGGGCAACGGGCGCTGGTGGTCGA
AATTATGGCGGAAGGGATGCGTAACCCACAGGTCGCCGCCATGCTTAAAAATAAGCATATGACGATCACTGAATTTGTTG
CCCAGCGGATGCGTGATGCCCAGCAAAAAGGCGAGATAAGCCCAGACATCAACACGTCAATGACTTCACGTTTACTGCTG
GATCTGACCTACGGTGTACTGGCCGATATCGAAGCGGAAGATCTGGCGCGTGAAGCGTCGTTTGCTCAGGGATTACGCGC
GATGATTGGCGGTATCTTAACCGCATCCTGA

Upstream 100 bases:

>100_bases
GCATACGAATAGAGTGTGCCTTCGCACTATTCAACAGCAATGATAGGCGCTCACCTGACAACGCGGTAAACTAGTTATTC
ACGCTAACTATAATGGTTTA

Downstream 100 bases:

>100_bases
TCCTCTCATTTCGCGGGCTGGTGATAACTGTGCCCGCGTTTCATACTTTAATTTCCCTGTACAAAATACAATCTAGCCGG
GATCGGAGAATTCCCCCCCA

Product: DNA-binding transcriptional repressor

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEG
IHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLL
DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS

Sequences:

>Translated_196_residues
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEG
IHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLL
DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS
>Mature_196_residues
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEG
IHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLL
DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=196, Percent_Identity=99.4897959183673, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21816; Mature: 21816

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
MLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLLDLTYGVLADIEAEDLAREAS
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FAQGLRAMIGGILTAS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
MLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLLDLTYGVLADIEAEDLAREAS
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FAQGLRAMIGGILTAS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]