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The map label for this gene is rstA

Identifier: 218695170

GI number: 218695170

Start: 1831065

End: 1831793

Strand: Direct

Name: rstA

Synonym: EC55989_1774

Alternate gene names: 218695170

Gene position: 1831065-1831793 (Clockwise)

Preceding gene: 218695168

Following gene: 218695171

Centisome position: 35.52

GC content: 49.11

Gene sequence:

>729_bases
GTGAATGTTATGAACACTATCGTATTTGTGGAAGATGATGCGGAAGTCGGTTCACTGATTGCCGCGTACCTGGCAAAACA
TGATATGCAGGTTACCGTAGAGCCGCGCGGCGACCAGGCCGAAGAAACCATTTTGCGAGAAAATCCGGATTTGGTGTTAC
TCGACATCATGCTACCAGGCAAGGACGGCATGACCATTTGTCGTGATTTACGCGCAAAGTGGTCTGGACCGATTGTTCTT
CTAACCTCTCTCGATAGCGATATGAACCACATCCTGGCACTGGAAATGGGTGCCTGCGACTATATTCTCAAAACGACGCC
CCCTGCTGTTTTGCTAGCGCGTTTACGTTTGCATTTGCGTCAGAATGAGCAAGCCACACTGAGCAAAGGTCTTCAGGAAA
CGTCTCTGACTCCCTACAAAGCCCTGCATTTCGGCACGTTGACCATCGATCCCATCAACCGCGTAGTCACCCTGGCTAAC
ACTGAAATCTCGCTCTCGACAGCTGATTTCGAATTATTGTGGGAATTAGCTACCCATGCCGGGCAAATCATGGACCGCGA
TGCATTGCTGAAAAATTTACGCGGCGTCAGTTATGACGGACTGGATCGTAGCGTGGACGTGGCTATTTCGCGGTTAAGAA
AAAAACTGCTCGATAACGCCGCAGAACCTTATCGCATTAAAACTGTGCGTAACAAAGGCTATCTTTTTGCGCCTCATGCA
TGGGAATAA

Upstream 100 bases:

>100_bases
CATAACAAGTCATCAGTAGAATACCTGATGAAAACTTGTTTAGAAACGATTGATAGTAAGTAAAAACAGCGCGGTGTATT
GTGACGTTTTTATATCTACC

Downstream 100 bases:

>100_bases
GCGATGAAAAAACTGTTTATCCAGTTTTACCTGTTATTGTTTGTCTGCTTCCTTGTGATGTCTCTGCTGGTTGGGTTGGT
GTACAAATTTACCGCCGAAC

Product: DNA-binding transcriptional regulator RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNVMNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVL
LTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLRQNEQATLSKGLQETSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE

Sequences:

>Translated_242_residues
MNVMNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVL
LTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLRQNEQATLSKGLQETSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE
>Mature_242_residues
MNVMNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVL
LTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLRQNEQATLSKGLQETSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=99.581589958159, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=34.3347639484979, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=33.0434782608696, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=32.4675324675325, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=34.061135371179, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.0472103004292, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=29.0598290598291, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.0429184549356, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=28.6324786324786, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=30.8695652173913, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=28.8793103448276, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1787375, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27035; Mature: 27035

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVMNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPG
CCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEECC
KDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHC
QNEQATLSKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEISLSTADFELLWELATHA
CCCHHHHHCCCHHCCCCCCHHEEEEEEEECCCCEEEEEECCEEEEEHHHHHHHHHHHHHH
GQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCC
WE
CC
>Mature Secondary Structure
MNVMNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPG
CCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEECC
KDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLR
CCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHC
QNEQATLSKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEISLSTADFELLWELATHA
CCCHHHHHCCCHHCCCCCCHHEEEEEEEECCCCEEEEEECCEEEEEHHHHHHHHHHHHHH
GQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCC
WE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]