Click here to switch to the map view.

The map label for this gene is mdtI

Identifier: 218695161

GI number: 218695161

Start: 1821735

End: 1822064

Strand: Reverse

Name: mdtI

Synonym: EC55989_1764

Alternate gene names: 218695161

Gene position: 1822064-1821735 (Counterclockwise)

Preceding gene: 218695162

Following gene: 218695157

Centisome position: 35.35

GC content: 51.82

Gene sequence:

>330_bases
ATGGCGCAGTTTGAATGGGTTCACGCCGCCTGGCTGGCATTGGCAATCGTGCTGGAAATCGTTGCTAACGTCTTTTTGAA
ATTTTCTGACGGCTTTCGTCGCAAAATATTTGGCTTGCTCTCCCTGGCGGCGGTGCTGGCTGCCTTTAGTGCGCTTTCTC
AGGCCGTAAAAGGGATCGACTTGTCTGTCGCTTATGCATTGTGGGGCGGGTTTGGTATTGCCGCCACGTTAGCCGCAGGT
TGGATCTTGTTTGGTCAACGGTTAAATCGTAAAGGCTGGATTGGCCTGGTCTTGCTGTTGGCTGGAATGATCATGGTGAA
ACTTGCCTGA

Upstream 100 bases:

>100_bases
TCGCTGATGAAAATTGCCGGGTTAACCACCCTGGTCGCCGGGATTGTGTTGATCAAATCAGGTACCCGTAAAGCGCGTAA
ACCTGAACTGGAGGTGAACC

Downstream 100 bases:

>100_bases
TGAAGACGCTGCCCGCACAGTCGGGCAGCGTTTGAACATTATTTTTGCGACAGTTGATCCAGCTTGTCGCGAAAACCGGT
AACAGAAATGGCCCGGTTAT

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WILFGQRLNRKGWIGLVLLLAGMIMVKLA

Sequences:

>Translated_109_residues
MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WILFGQRLNRKGWIGLVLLLAGMIMVKLA
>Mature_108_residues
AQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGW
ILFGQRLNRKGWIGLVLLLAGMIMVKLA

Specific function: Catalyzes the excretion of spermidine

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=100, Blast_Score=204, Evalue=1e-54,
Organism=Escherichia coli, GI1786755, Length=98, Percent_Identity=34.6938775510204, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MDTI_ECO24 (A7ZM58)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001462887.1
- ProteinModelPortal:   A7ZM58
- STRING:   A7ZM58
- EnsemblBacteria:   EBESCT00000019323
- GeneID:   5589814
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1806
- eggNOG:   COG2076
- GeneTree:   EBGT00050000009344
- HOGENOM:   HBG740972
- OMA:   IAIGVEI
- ProtClustDB:   PRK10650
- BioCyc:   ECOL331111:ECE24377A_1806-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01597
- InterPro:   IPR000390

Pfam domain/function: PF00893 Multi_Drug_Res

EC number: NA

Molecular weight: Translated: 11720; Mature: 11589

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x409c1818)-; HASH(0x19ca0188)-; HASH(0x19cd26ec)-; HASH(0x19ccf3b8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
AQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA