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The map label for this gene is celA

Identifier: 218695070

GI number: 218695070

Start: 1736394

End: 1737839

Strand: Reverse

Name: celA

Synonym: EC55989_1668

Alternate gene names: 218695070

Gene position: 1737839-1736394 (Counterclockwise)

Preceding gene: 218695071

Following gene: 218695066

Centisome position: 33.71

GC content: 45.09

Gene sequence:

>1446_bases
TTGTGTATGTCAGGATTTAAAAAAGGTTTTTTATGGGGCGGTGCGGTAGCCGCGCATCAGTTGGAAGGTGGCTGGAATGA
AGGAGGAAAAGGCATCAGCATCGCTGATGTGATGACTGCTGGCGCTCACGGGGTGCCGCGTGAAGTGACAGAAGGCGTTA
TCGACGGGCTTAATTATCCCAATCATGAAGCAATTGATTTTTATCATCGCTATAAAACAGATATTCAGTTATTTGCCGAG
ATGGGATTCAAATGCTTTCGAACTTCCATTGCCTGGACACGAATCTTTCCGCAAGGTGACGAACAGGAGCCGAATGAAGA
GGGTTTACAATTTTATGATGATCTGTTCGATGAATGCCTTAAGCAGGGAATGGAACCTGTGGTGACGCTTTCACATTTTG
AGATGCCTTATCATCTGGTGACAAAATATGGTGGCTGGCGAAACCGTAAACTGATCGACTTTTTTATCCGCTTCGCATCA
ACGGTCTTCACGCGCTATAAAGAAAAAGTAAAGTACTGGATGACGTTTAACGAAATCAATAATCAGGTGAATTTCAGCGA
AAGCCTGTGTCCATTTACTAATTCCGGTATCTTGTATTCGCCAGAGGAAGATATCAATGAGCGCGAACAAATAATGTACC
AGGCGGTACATTACGAGTTAGTTGCCAGTGCCCTGGCGGTACAGACTGGAAAATCGATCAATCCTGAATTTAACATTGGC
TGTATGATCGCCATGTGTCCCATCTATCCTCTGACGTGTGCACCCAACGATATGATGATGGCCACGAAAGCAATGCATCG
TCGTTACTGGTTTACTGATGTTCATGCTCGTGGATATTATCCGCAACATATGCTGAATTACTTTGCCAGGAAAGGATTCA
ACCTCGATATCACACCAGAAGATAACGCGATTCTTGCCAGTGGTTGTGTCGACTTTATCGGCTTTAGCTACTACATGTCT
TTTACGACACAATTTTCGCCCGATAACCCGCAACTGGATTATGTTGAACCACGAGATTTGGTCAGCAACCCTTATATCGA
TACATCCGAATGGGGATGGCAAATTGATCCGGCAGGGCTACGTTATTCACTCAACTGGTTCTGGGATCATTTCCAGTTGC
CGCTGTTTATTGTCGAAAATGGATTTGGTGCGGTTGACCAGAGACAAGCTGACGGCACGGTGAACGATCACTATCGCATT
GATTACTTTGCTTCCCATATTCGGGAAATGAAAAAAGCCGTAGTTGAAGATGGTGTTGACTTAATTGGCTACACCCCGTG
GGGCTGCATTGACCTGGTTTCTGCCGGAACAGGGGAAATGAAAAAGCGCTACGGAATGATTTATGTCGATAAAGACAACG
AAGGGAAGGGAACGCTGGAACGGATACGTAAAGCGTCGTTTTACTGGTATCGGGATCTCATCGCCAACAATGGCGAAAAT
ATTTGA

Upstream 100 bases:

>100_bases
TAACGAATTATCGAATTTTAAGTTTAATGAGAACAGCAAAGACGAGTTTATGGCCGGCATCCAGGCGGAAGTCTGGTGGT
AATCTATTTTAGTTAAGGAG

Downstream 100 bases:

>100_bases
GACTTGAGGAAGATATTACGGAGATGTCAGGCTCTGTGATCAGAGCCTGACAATAACTACATAGCGTGTTGATTATAATA
GGGCACGCCGAGCGCATCCG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MCMSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYKTDIQLFAE
MGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFAS
TVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIG
CMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPEDNAILASGCVDFIGFSYYMS
FTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRI
DYFASHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGEN
I

Sequences:

>Translated_481_residues
MCMSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYKTDIQLFAE
MGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFAS
TVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIG
CMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPEDNAILASGCVDFIGFSYYMS
FTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRI
DYFASHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGEN
I
>Mature_481_residues
MCMSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYKTDIQLFAE
MGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFAS
TVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIG
CMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPEDNAILASGCVDFIGFSYYMS
FTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRI
DYFASHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGEN
I

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=499, Percent_Identity=28.8577154308617, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI32481206, Length=493, Percent_Identity=27.3833671399594, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI13273313, Length=492, Percent_Identity=26.0162601626016, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=30.142566191446, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI28376633, Length=485, Percent_Identity=27.2164948453608, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI2367174, Length=475, Percent_Identity=60.2105263157895, Blast_Score=609, Evalue=1e-175,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=48.8612836438923, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI2367270, Length=479, Percent_Identity=50.3131524008351, Blast_Score=466, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17552856, Length=489, Percent_Identity=28.4253578732106, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=27.6639344262295, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356577, Length=490, Percent_Identity=28.1632653061224, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 55422; Mature: 55422

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCMSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYP
CCCCCCCCCCEECCHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHHHHHCCCCC
NHEAIDFYHRYKTDIQLFAEMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECL
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFASTVFTRYKEKVKYWMTFNEIN
HHCCCCEEEHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHC
NQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIG
CCCCCCCCCCCCCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
CMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPE
EEEEECCCCEEECCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCCEEECCC
DNAILASGCVDFIGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGL
CCCEEHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCC
RYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRIDYFASHIREMKKAVVEDGVD
EEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCC
LIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGEN
EECCCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
I
C
>Mature Secondary Structure
MCMSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYP
CCCCCCCCCCEECCHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHHHHHCCCCC
NHEAIDFYHRYKTDIQLFAEMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECL
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFASTVFTRYKEKVKYWMTFNEIN
HHCCCCEEEHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHC
NQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYELVASALAVQTGKSINPEFNIG
CCCCCCCCCCCCCCCCEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
CMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPE
EEEEECCCCEEECCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCCEEECCC
DNAILASGCVDFIGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGL
CCCEEHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCEECCCCC
RYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRIDYFASHIREMKKAVVEDGVD
EEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCC
LIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRDLIANNGEN
EECCCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]