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The map label for this gene is fimA [H]

Identifier: 218695044

GI number: 218695044

Start: 1704987

End: 1705598

Strand: Reverse

Name: fimA [H]

Synonym: EC55989_1639

Alternate gene names: 218695044

Gene position: 1705598-1704987 (Counterclockwise)

Preceding gene: 218695045

Following gene: 218695043

Centisome position: 33.09

GC content: 44.77

Gene sequence:

>612_bases
TTGTTAACCCTCTTTATTCAGCTACTTAAATATAAATTTTGGAGAATTATGAAACTCAAACATGTTGGTATGATTGTCGT
TTCTGTGTTGGCGATGTCGTCTGCTGCGGTAAGCGCAGCCGAGGGTGATGAATCAGTAACGACCACTGTTAATGGCGGTG
TTATTCATTTTAAAGGTGAAGTGGTAAATGCCGCTTGTGCAATTGATTCAGAATCAATGAACCAAACGGTTGAGCTGGGT
CAGGTTCGTTCTTCTCGCCTGGCTAAAGCGGGTGACCTCAGCTCCGCCGTTGGCTTCAATATCAAGCTGAATGATTGTGA
TACCAATGTTTCCAGTAATGCAGCTGTTGCATTCCTGGGTACTACTGTCACCAGTAATGACGATACGTTAGCGCTGCAGA
GTTCAGCGGCAGGCTCTGCCCAAAATGTCGGTATTCAAATTTTGGACCGTACGGGTGAGGTATTAATACTTGATGGGGCC
ACTTTTAGTGTTAAAACCGACTTGATTGATGGCACGAATATACTGCCATTCCAGGCTCGTTATATTGCTCTCGGGCAGTC
CGTAGCTGGTACTGCAAACGCTGATGCGACCTTCAAAGTTCAATATCTATAA

Upstream 100 bases:

>100_bases
ATCGTTCTTCGTGAAATGTAATAACCCTGGAAACTATATTCTCAGGGCAACAACCAATCAAGAATGATTCTTGTTTTTAA
GCAATAACAGAATGACTTAA

Downstream 100 bases:

>100_bases
TTCAATCTTAAGGTGGCTATACGTCATCTGAAATTGAAACAGGGTGTGTGTGGCATGGCTACGCACACCCGAGCAATTTA
CCAATATTCATCTCATTTTT

Product: putative major fimbrial subunit FmlA

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLTLFIQLLKYKFWRIMKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGEVVNAACAIDSESMNQTVELG
QVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAFLGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGA
TFSVKTDLIDGTNILPFQARYIALGQSVAGTANADATFKVQYL

Sequences:

>Translated_203_residues
MLTLFIQLLKYKFWRIMKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGEVVNAACAIDSESMNQTVELG
QVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAFLGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGA
TFSVKTDLIDGTNILPFQARYIALGQSVAGTANADATFKVQYL
>Mature_203_residues
MLTLFIQLLKYKFWRIMKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGEVVNAACAIDSESMNQTVELG
QVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAFLGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGA
TFSVKTDLIDGTNILPFQARYIALGQSVAGTANADATFKVQYL

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=154, Percent_Identity=70.1298701298701, Blast_Score=207, Evalue=3e-55,
Organism=Escherichia coli, GI87081753, Length=160, Percent_Identity=48.75, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082421, Length=187, Percent_Identity=32.620320855615, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786938, Length=160, Percent_Identity=30.625, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081804, Length=188, Percent_Identity=32.4468085106383, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786746, Length=149, Percent_Identity=32.8859060402685, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787781, Length=152, Percent_Identity=30.9210526315789, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 21268; Mature: 21268

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLFIQLLKYKFWRIMKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCEEEEECC
VVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAFLG
EEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEEEECCCCCCCCCEEEEEEE
TTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGATFSVKTDLIDGTNILPFQAR
EEEECCCCEEEEECCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCCEE
YIALGQSVAGTANADATFKVQYL
EEEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MLTLFIQLLKYKFWRIMKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCEEEEECC
VVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAFLG
EEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEEEEECCCCCCCCCEEEEEEE
TTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGATFSVKTDLIDGTNILPFQAR
EEEECCCCEEEEECCCCCCCCCCCEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCCEE
YIALGQSVAGTANADATFKVQYL
EEEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]