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The map label for this gene is ybjS

Identifier: 218694342

GI number: 218694342

Start: 967092

End: 968105

Strand: Reverse

Name: ybjS

Synonym: EC55989_0913

Alternate gene names: 218694342

Gene position: 968105-967092 (Counterclockwise)

Preceding gene: 218694343

Following gene: 218694339

Centisome position: 18.78

GC content: 54.44

Gene sequence:

>1014_bases
ATGAAGGTACTGGTTACCGGCGCCACCAGCGGCTTAGGTCGAAACGCGGTAGAGTTTTTATGCCAGAAAGGCATCAGCGT
GCGAGCGACCGGTCGCAACGAGGCAATGGGCAAATTGCTGGAAAAAATGGGCGCAGAGTTTGTTCCGGCGGATCTGACCG
AGCTGGTTTCATCACAAGCTAAAGTGATGCTCGCGGGCATTGATACGCTGTGGCACTGCTCCAGCTTTACCTCACCCTGG
GGGACACAACAGGCTTTCGATCTGGCTAACGTTCGCGCCACTCGCCGCCTGGGTGAATGGGCTGTCGCCTGGGGTGTGCG
TAACTTTATTCATATCTCTTCCCCCTCCCTGTACTTCGATTATCACCACCATCGCGATATTAAAGAAGATTTTCGCCCTC
ACCGCTTCGCCAACGAGTTTGCCCGCAGCAAAGCAGCCAGCGAAGAAGTGATCAATATGCTTTCGCAGGCGAATCCACAA
ACGCGCTTTACTATTCTGCGCCCACAAAGTCTGTTCGGACCGCACGATAAAGTCTTTATTCCCCGTCTGGCGCATATGAT
GCACCACTACGGCAGTATTCTGTTACCGCATGGCGGCAGTGCGCTGGTCGATATGACCTACTATGAAAATGCCGTGCACG
CAATGTGGCTGGCAAGCCAGGAAGCCTGCGATAAGCTACCTTCCGGGCGTGTGTACAACATCACCAACGGCGAGCATCGC
ACACTGCGCAGCATCGTGCAGAAGCTGATCGACGAGTTGAATATTGACTGTCGTATTCGTTCCGTCCCCTACCCGATGCT
GGATATGATCGCCCGCAGCATGGAGCGTTTAGGCCGCAAGTCAGCAAAAGAGCCGCCGCTGACCCACTACGGCGTCTCCA
AGTTGAATTTTGACTTTACGCTGGATATTACGCGTGCGCAGGAAGAGTTAGGTTATCAGCCGGTCATCACCCTGGATGAA
GGTATCGAGAAAACTGCCGCCTGGCTACGCGACCACGGAAAACTGCCGCGCTAA

Upstream 100 bases:

>100_bases
AATCGACAAAACCTGCGTTATTCTTTCATGTTTCCCATTGCATCATGGGGGAAATCACGGAAGAATGCGCACGTTATTTT
CTCAACAACAGTGGATTGAT

Downstream 100 bases:

>100_bases
TCCTGCCCGTATTTCTCCAGCAATGCTTCGGCAATCGCCTGAGTTTCTGCATCCGCTTCGCCGTTATATAACGTCGGGCG
GAAATGCATCTGGAATGCCA

Product: putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPW
GTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPSGRVYNITNGEHR
TLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDE
GIEKTAAWLRDHGKLPR

Sequences:

>Translated_337_residues
MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPW
GTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPSGRVYNITNGEHR
TLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDE
GIEKTAAWLRDHGKLPR
>Mature_337_residues
MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPW
GTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPSGRVYNITNGEHR
TLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDE
GIEKTAAWLRDHGKLPR

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI193211614, Length=338, Percent_Identity=23.9644970414201, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI8393516, Length=338, Percent_Identity=23.9644970414201, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI239745448, Length=332, Percent_Identity=24.3975903614458, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI310132178, Length=332, Percent_Identity=24.3975903614458, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310113012, Length=332, Percent_Identity=24.3975903614458, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081792, Length=337, Percent_Identity=100, Blast_Score=707, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570557, Length=233, Percent_Identity=27.4678111587983, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321437, Length=294, Percent_Identity=25.5102040816327, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBJS_ECOLI (P75821)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D64825
- RefSeq:   AP_001499.1
- RefSeq:   NP_415389.2
- ProteinModelPortal:   P75821
- SMR:   P75821
- STRING:   P75821
- EnsemblBacteria:   EBESCT00000003594
- EnsemblBacteria:   EBESCT00000016892
- GeneID:   945495
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5819
- KEGG:   eco:b0868
- EchoBASE:   EB3452
- EcoGene:   EG13688
- eggNOG:   COG0451
- GeneTree:   EBGT00050000008808
- HOGENOM:   HBG755066
- OMA:   GQDESGI
- ProtClustDB:   CLSK879799
- BioCyc:   EcoCyc:G6453-MONOMER
- Genevestigator:   P75821
- InterPro:   IPR001509
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01370 Epimerase

EC number: NA

Molecular weight: Translated: 38086; Mature: 38086

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQA
CEEEEECCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFD
EEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEE
YHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFTILRPQSLFGPHDKVFI
CHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCHHHH
PRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPSGRVYNITNGEHR
HHHHHHHHHHCCEEEECCCCEEEEEHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCCHHH
TLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFT
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEE
LDITRAQEELGYQPVITLDEGIEKTAAWLRDHGKLPR
EEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQA
CEEEEECCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFD
EEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEE
YHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFTILRPQSLFGPHDKVFI
CHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHCCCCCHHHH
PRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPSGRVYNITNGEHR
HHHHHHHHHHCCEEEECCCCEEEEEHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCCHHH
TLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFT
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEE
LDITRAQEELGYQPVITLDEGIEKTAAWLRDHGKLPR
EEEEHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503