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The map label for this gene is kdpE

Identifier: 218694120

GI number: 218694120

Start: 736788

End: 737465

Strand: Reverse

Name: kdpE

Synonym: EC55989_0678

Alternate gene names: 218694120

Gene position: 737465-736788 (Counterclockwise)

Preceding gene: 218694121

Following gene: 218694119

Centisome position: 14.31

GC content: 57.37

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCTATTCGTCGCTTTCTGCGCACGGCGCTGGAGGGCGACGGGATGCG
CGTCTATGAGGCCGAAACGCTGCAACGCGGCTTGCTGGAAGCGGCTACCCGTAAGCCAGATTTGATTATTCTCGATCTCG
GCCTGCCCGATGGTGATGGGATTGAGTTTATCCGCGACCTGCGCCAGTGGAGCGCGGTGCCGGTGATTGTGCTTTCCGCA
CGCAGCGAAGAGAGCGACAAGATCGCCGCGCTGGATGCCGGAGCGGATGATTATCTGAGTAAGCCGTTTGGCATTGGCGA
ATTGCAGGCCCGTCTGCGCGTCGCTTTACGCCGCCACTCCGCCACCGCCGCGCCCGATCCGCTGGTGAAATTTTCCGATG
TTACCGTCGATTTAGCCGCCCGCGTGATTCACCGGGGTGAGGAAGAGGTGCATCTCACGCCGATTGAGTTCCGCCTGCTG
GCGGTGCTGCTGAATAATGCCGGGAAAGTGCTCACCCAGCGCCAGTTACTCAATCAGGTGTGGGGGCCAAACGCGGTCGA
ACACAGTCACTATTTGCGTATTTATATGGGACATCTGCGACAAAAACTGGAACAGGATCCCGCTCGCCCCCGCCATTTCA
TTACTGAAACCGGTATTGAGTATCGGTTTATGCCATGA

Upstream 100 bases:

>100_bases
GCACTATTACCGCGTTCAACCGACCGGAAGGTGGTGCCTGTTTTCGTGTTACACTTCCCCAGCAAACCGCTCCTGAACTT
GAAGACTTTCATGAGGATAT

Downstream 100 bases:

>100_bases
ATGTTTATTCAATAAATGCGCTTAAATAATTATTAATTTATTATTAAACCTGCCAAAAATATTATTATTTGGCAGGTTTA
ATTTCTTAACGCAAATATAA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIEYRFMP

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIEYRFMP
>Mature_224_residues
TNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIEYRFMP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=98.6607142857143, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.322869955157, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=35.1351351351351, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790860, Length=205, Percent_Identity=37.5609756097561, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=33.1896551724138, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=201, Percent_Identity=35.8208955223881, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.5315315315315, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=33.7962962962963, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.2869955156951, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.0043668122271, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=218, Percent_Identity=29.8165137614679, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI2367329, Length=210, Percent_Identity=31.4285714285714, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693140, Length=245, Percent_Identity=28.1632653061224, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=33.8842975206612, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=30.8823529411765, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=30.5343511450382, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25405; Mature: 25273

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIEYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIEYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]