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The map label for this gene is hokE

Identifier: 218694022

GI number: 218694022

Start: 624245

End: 624397

Strand: Direct

Name: hokE

Synonym: EC55989_0573

Alternate gene names: 218694022

Gene position: 624245-624397 (Clockwise)

Preceding gene: 218694016

Following gene: 218694025

Centisome position: 12.11

GC content: 47.06

Gene sequence:

>153_bases
ATGCTGACGAAATATGCCCTTGCGGCAGTCATAGTGCTGTGTTTAACGGTGCTGGGATTTACGCTTCTGGTCGGGGATTC
GCTGTGTGAGTTCACCGTAAAGGAACGTAATATTGAGTTTAAGGTTGTTCTCGCTTACGAACCGAAGAAGTAG

Upstream 100 bases:

>100_bases
ATGAAGCCCCAGGACGATATTTCTATCAACCCTGGGGCTACCTACCCAAACCTGAACAATTTGGATGGTAGTCCCTTCTT
CGCATGGAGGCAATATAAAC

Downstream 100 bases:

>100_bases
CCGTTGTGCGGGGAGCAATCCCCGCATATCCGGTTGTCAGGTCAGGATGGTAAGGCACCTGCTTTACACTTTCGCCCGCG
GTCAGTGATGGCTGCGGGCG

Product: toxic polypeptide, small

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 50; Mature: 50

Protein sequence:

>50_residues
MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVLAYEPKK

Sequences:

>Translated_50_residues
MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVLAYEPKK
>Mature_50_residues
MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVLAYEPKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994879, Length=50, Percent_Identity=98, Blast_Score=98, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 5592; Mature: 5592

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVLAYEPKK
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEEEEECCCC
>Mature Secondary Structure
MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVLAYEPKK
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]