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The map label for this gene is cusB

Identifier: 218694014

GI number: 218694014

Start: 613912

End: 615135

Strand: Direct

Name: cusB

Synonym: EC55989_0565

Alternate gene names: 218694014

Gene position: 613912-615135 (Clockwise)

Preceding gene: 218694013

Following gene: 218694015

Centisome position: 11.91

GC content: 55.72

Gene sequence:

>1224_bases
ATGAAAAAAATCGCGCTTATTATCGGCAGCATGATCGCGGGCGGTATTATTTCTGCGGCAGGTTTTACCTGGTTTGCAAA
GGCTGAACCACCCGCAGAAAAAACGTCGACCGCAGAACGTAAAATCTTATTCTGGTACGACCCGATGTACCCCAATACGC
GGTTCGATAAACCAGGTAAATCGCCGTTTATGGATATGGATCTGGTGCCGAAATATGCCGATGAAGAGAGTTCTGCGTCT
GGTGTGCGCATTGACCCGACTCAGACGCAGAATCTGGGGGTGAAAACGGCTACCGTCACGCGCGGGCCGCTGACTTTTGC
CCAGAGTTTCCCGGCGAATGTCAGTTACAACGAGTATCAGTATGCCATTGTGCAGGCTCGCGCTGCCGGGTTTATCGACA
AGGTGTATCCGCTTACCGTGGGCGATAAAGTACAAAAGGGCACACCGCTTCTCGACCTGACCATTCCTGACTGGGTGGAA
GCGCAGAGTGAGTATTTACTGCTGCGCGAAACCGGCGGTACGGCGACCCAGACTGAAGGCATTCTTGAGCGGCTGCGACT
GGCGGGAATGCCGGAGGCGGATATTCGCCGCCTGATCGCCACGCAAAAAATCCAGACTCGCTTTACGCTCAAAGCGCCCA
TTGATGGCGTGATCACCGCGTTTGATCTGCGCGCGGGAATGAATATCGCCAAAGATAACGTGGTCGCGAAAATTCAGGGT
ATGGACCCGGTGTGGGTCACTGCTGCGATCCCGGAGTCCATCGCCTGGCTGGTGAAAGATGCCTCGCAGTTTACCCTCAC
CGTTCCGGCGCGACCGGATAAAACACTCACCATCCGCAAATGGACGCTGCTACCTGGCGTGGATGCCGCGACCCGCACGC
TGCAGCTGCGTCTGGAAGTCGACAACGCCGACGAGGCGCTAAAACCGGGAATGAACGCCTGGTTGCAACTCAATACCGCC
AGCGAACCGATGCTGCTCATTCCGTCACAGGCGCTGATTGATACCGGCAACGAACAGCGGGTGATTACCGTTGATGCCGA
CGGACGCTTTGTACCGAAACGCGTTGCCGTTTTCCAGGCATCGCAAGGCGTCACCGCGTTACACTCTGGTCTGGCGGAAG
GTGAAAAGGTGGTTTCCAGCGGCCTGTTCCTGATTGATTCCGAAGCCAATATTTCTGGCGCACTGGAGCGGATGCGCTCT
GAAAGTGCTACCAATGCGCATTGA

Upstream 100 bases:

>100_bases
AATTAAAACCGGCGACAAAGTGGCGTTTAATTTTGTCCAGCAGGGCAACCTTTCTTTATTACAGGATATTAAAGTCAGCC
AGTAACCCAGGTTTAATGAG

Downstream 100 bases:

>100_bases
GGGAATAACCAATGATTGAATGGATTATTCGTCGCTCGGTGGCGAACCGTTTTTTGGTGCTGATGGGCGCGTTGTTTCTG
AGCATCTGGGGCACCTGGAC

Product: copper/silver efflux system membrane fusion protein CusB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGNEQRVITVDADGRFVPKRVAVFQASQGVTALHSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATNAH

Sequences:

>Translated_407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGNEQRVITVDADGRFVPKRVAVFQASQGVTALHSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATNAH
>Mature_407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGNEQRVITVDADGRFVPKRVAVFQASQGVTALHSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATNAH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=407, Percent_Identity=99.017199017199, Blast_Score=816, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44338; Mature: 44338

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGK
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEEEEECCCCCCCCCCCCCC
SPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQ
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCEE
YAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEG
EEEEEEHHHCCHHHEEEEECCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCCCCHHHHH
ILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
HHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEEEEC
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEV
CCCEEEEEECHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEE
DNADEALKPGMNAWLQLNTASEPMLLIPSQALIDTGNEQRVITVDADGRFVPKRVAVFQA
CCCHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCCCCEEEEECCCCCCCCCEEEEEEC
SQGVTALHSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATNAH
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGK
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEEEEECCCCCCCCCCCCCC
SPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQ
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCEE
YAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVEAQSEYLLLRETGGTATQTEG
EEEEEEHHHCCHHHEEEEECCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCCCCHHHHH
ILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
HHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEEEEC
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEV
CCCEEEEEECHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEE
DNADEALKPGMNAWLQLNTASEPMLLIPSQALIDTGNEQRVITVDADGRFVPKRVAVFQA
CCCHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCCCCEEEEECCCCCCCCCEEEEEEC
SQGVTALHSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATNAH
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]