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The map label for this gene is envY

Identifier: 218694000

GI number: 218694000

Start: 592657

End: 593418

Strand: Reverse

Name: envY

Synonym: EC55989_0551

Alternate gene names: 218694000

Gene position: 593418-592657 (Counterclockwise)

Preceding gene: 218694001

Following gene: 218693999

Centisome position: 11.51

GC content: 45.8

Gene sequence:

>762_bases
ATGCAATTGAGCAGCAGTGAACCTTGCGTGGTGATCCTGACCGAAAAAGAGGTAGAGGTAAGCGTCAATAACCATGCTAC
GTTTACCCTTCCGAAAAACTACCTGGCCGCCTTCGCGTGCAACAATAACGTCATTGAACTCTCAACGTTAAATCACGTAT
TAATCACCCACATCAACCGTAACATCATCAACGATTATCTGTTGTTTTTAAATAAGAACTTAACCTGTGTAAAGCCCTGG
TCGCGGCTGGCAACCCCGGTTATTGCTTGTCATAGCCGTACACCGGAAGTGTTCCGGCTAGCCGCCAACCACAGCAAGCA
GCAACCCAGCAAACCCTGCGAAGCGGAGTTGACGCGCGTATTGCTTTTTACCGTATTGTCTAACTTTCTTGAGCAATCGC
GGTTTATTGCCCTACTGATGTATATCTTACGCAGCAGCGTCCGCGACAGCGTCTGCCGCATTATTCAAAGCGATATTCAG
CATTACTGGAATCTGCGAATTGTCGCCAGTTCGCTATGTTTAAGCCCCAGCCTGCTCAAAAAGAAATTAAAAAACGAAAA
TACCAGCTATAGCCAGATTGTCACAGAGTGTCGTATGCGTTACGCCGTACAGATGTTATTGATGGATAACAAAAATATCA
CTCAGGTGGCGCAATTATGTGGCTATAGCAGCACGTCATACTTTATCTCTGTTTTTAAGGCGTTTTACGGCCTGACACCG
TTGAATTATCTCGCCAAACAGCGACAAAAAGTGATGTGGTGA

Upstream 100 bases:

>100_bases
CGTGCTAAAGAAAGAAGATCGTTATCGGCGAACGGGCCGATCACTCATGCAGGAAGCATAGATCCTTTGAGCGGAGTTTC
TGATATCTGAGGAGTGCGAA

Downstream 100 bases:

>100_bases
AGGGCAAAGCGGAAACGGATAAGACTGGCATAAATGAAGAAGAAATGGCGCGCCCTGCAGGATTCGAACCTGCGGCCCAC
GACTTAGAAGGTCGTTGCTC

Product: DNA-binding transcriptional activator of porin biosynthesis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRVLLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW

Sequences:

>Translated_253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRVLLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW
>Mature_253_residues
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRVLLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW

Specific function: Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins ompF and ompC and the lambda receptor, lamB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786778, Length=253, Percent_Identity=99.2094861660079, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI1790557, Length=252, Percent_Identity=56.3492063492063, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1789933, Length=194, Percent_Identity=38.659793814433, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786776, Length=96, Percent_Identity=43.75, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789932, Length=127, Percent_Identity=40.1574803149606, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787776, Length=124, Percent_Identity=38.7096774193548, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 29019; Mature: 29019

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINR
CCCCCCCCEEEEEECCCEEEEECCCEEEEECHHHHEEEEECCCEEEEEHHHHHHHHHHHH
NIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRV
HHHHHHHHHHCCCCEEECCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQHYWNLRIVASSLCLSPSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCH
LNYLAKQRQKVMW
HHHHHHHHHHCCC
>Mature Secondary Structure
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINR
CCCCCCCCEEEEEECCCEEEEECCCEEEEECHHHHEEEEECCCEEEEEHHHHHHHHHHHH
NIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRV
HHHHHHHHHHCCCCEEECCHHHHCCHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
LLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQHYWNLRIVASSLCLSPSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCH
LNYLAKQRQKVMW
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536924; 8905232; 9278503 [H]