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The map label for this gene is sgrR

Identifier: 218693539

GI number: 218693539

Start: 76064

End: 77719

Strand: Reverse

Name: sgrR

Synonym: EC55989_0067

Alternate gene names: 218693539

Gene position: 77719-76064 (Counterclockwise)

Preceding gene: 218693541

Following gene: 218693538

Centisome position: 1.51

GC content: 55.37

Gene sequence:

>1656_bases
ATGCCATCTGCTCGTCTGCAACAACAGTTCATCCGCCTGTGGCAATGCTGCGAGGGTAAATCGCAGGACACAACGCTCAA
CGAACTGGCAGCGTTATTGAGCTGCTCGCGTCGTCATATGCGTACCCTGCTCAACACCATGCAGGATCGCGGCTGGCTGA
CGTGGGAAGCGGAAGTCGGGCGCGGTAAACGCTCGCGTCTGACATTCCTCTATACCGGGCTGGCGCTTCAGCAACAGCGG
GCGGAAGACCTGCTGGAGCAGGATCGTATCGACCAACTAGTGCAGTTGGTTGGCGACAAAGCGACTGTGCGGCAAATGCT
GGTTTCTCATCTGGGCCGCAGCTTCCGCCAGGGGCGGCACATCCTGCGCGTGCTCTACTATCGTCCGTTGCGTAATCTGC
TACCTGGCAGCGCATTGCGCCGTTCCGAAACCCATATTGCCCGGCAAATCTTCAGTTCGCTAACGCGCATAAATGAGGAA
AATGGGGAACTGGAAGCAGACATCGCCCACCACTGGCAGCAAATATCACCGCTTCACTGGCGTTTCTTTTTGCGTCCAGG
AGTCCATTTTCATCATGGTCGTGAACTGGAAATGGACGACGTGATCGCCTCTTTAAAACGAATCAATACGCTGCCGCTCT
ATTCGCATATTGCGGACATTGTGTCGCCGACGCCCTGGACGCTGGATATCCATCTCACGCAACCGGACCGCTGGTTACCG
TTACTGCTGGGACAAGTTCCGGCGATGATCCTGCCGCGCGAATGGGAAACCCTCAGTAACTTTGCCAGCCATCCCATCGG
CACCGGTCCGTATGCGGTGATCCGCAACACCACCAATCAACTGAAAATTCAGGCATTCGATGACTTCTTCGGTTACCGGG
CATTAATCGATGAAGTTAACGTCTGGGTTCTGCCGGAAATTGCCGACGAGCCAGCTGGAGGTCTGATGCTAAAAGGTCCA
CAGGGCGAGGAAAAAGAGATTGAAAGCCGCCTGGAGGAAGGTTGCTACTATTTACTGTTCGACAGCCGCACCCATCGCGG
GGCGAATCAGCAAGTCAGGGACTGGGTAAGCTATGTGCTTTCTCCAACTAATCTGGTCTATTTCGCTGAGGAACAGTACC
AGCAACTGTGGTTCCCGGCTTATGGACTGCTCCCCCGTTGGCACCATGCCCGCACCATAAAGAGCGAAAAACCGGCTGGC
CTGGAAAGCCTCACCCTGACCTTTTATCAGGATCACAGTGAGCATCGGGTGATTGCCGGGATCATGCAGCAGATTCTGGC
AAGTCACCAGGTCACGCTGGAAATCAAAGAGATCAGCTACGATCAGTGGCATGAAGGAGAGATCGAGAGCGATATCTGGC
TTAATAGCGCCAACTTTACGCTGCCGCTGGATTTTTCGCTGTTCGCGCACTTGTGCGAGGTGCCGCTGCTCCAACACTGT
ATTCCGATCGACTGGCAAGCCGACGCCGCCCGCTGGCGCAATGGCGAAATGAACCTGGCGAACTGGTGCCAGCAACTGGT
CGCCAGTAAAGCAATGGTGCCGCTTATCCACCACTGGCTGATCATTCAGGGGCAACGCAGTATGCGCGGCCTGCGCATGA
ATACCCTCGGCTGGTTCGATTTTAAATCAGCGTGGTTTGCGCCACCGGATCCATGA

Upstream 100 bases:

>100_bases
AAACTGACGCATGGGGCACCTCCTTGCTTCATCGTTAGGAATTATTGACTTAATATAGGGAAAATAAAATTGCTGTCTTT
TGCGCAGGAGTTCCCCTTTT

Downstream 100 bases:

>100_bases
TTGCTGGTTGATAACAAAATCACTACACTAACGCCGTTCTCAACGGGGTGCCACGCAGACGCGTGCGCTGAGAAAATACC
CGTCGAACCTGATCCGGATA

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAG
LESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Sequences:

>Translated_551_residues
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAG
LESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>Mature_550_residues
PSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRA
EDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEEN
GELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPL
LLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQ
GEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGL
ESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCI
PIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=551, Percent_Identity=98.9110707803993, Blast_Score=1129, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=579, Percent_Identity=27.2884283246978, Blast_Score=178, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64005; Mature: 63874

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVG
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCC
VWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAG
CCCCEEEEEHHHHHHHHCCHHHCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDP
CCCCCCCCCCC
>Mature Secondary Structure 
PSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVG
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRH
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHW
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEE
RFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLP
EEEECCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHH
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVN
HHHHCCCHHCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHCCC
VWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVL
EEEECCCCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
SPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAG
CCCCEEEEEHHHHHHHHCCHHHCCCCHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHH
IMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
HHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHC
IPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFD
CCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHCCCEECCCCCCC
FKSAWFAPPDP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]