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The map label for this gene is hha [H]

Identifier: 218692858

GI number: 218692858

Start: 53308

End: 53517

Strand: Reverse

Name: hha [H]

Synonym: p1ECUMN_0072

Alternate gene names: 218692858

Gene position: 53517-53308 (Counterclockwise)

Preceding gene: 218692859

Following gene: 218692857

Centisome position: 43.76

GC content: 36.67

Gene sequence:

>210_bases
ATGGCGAAAACAAAACAGGAATGGCTGTATCAGTTACGGCGATGTTCATCAGTCAATACGCTGGAAAAAATTATTCATAA
AAACAGAGACAGTTTATTAAACAGTGAACGTGAATCATTTAATTCAGCAGCAGACCACCGGTTAGCGGAATTAATCACCG
GAAAGTTATATGACAGGATACCAAAAGAGATATGGAAATATGTAAGGTAA

Upstream 100 bases:

>100_bases
GCTCTGGTCAGATGCTGATCCGGTTCCCCCCTGGATATGGAGACACCGTAAATAAAGCGATGGCAATCTTATCATTCATC
TGTTCTCAGCGGGAATAAAA

Downstream 100 bases:

>100_bases
TAATTCAGCATAATTAATTACCAGGAGCAGATAAACAATGAAGCTGATTATTTTTATTCTTATTGTTCTGATTATTGCAG
CGTTACTTATCCGGATTATC

Product: hemolysin expression-modulating protein hmo

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAADHRLAELITGKLYDRIPKEIWKYVR

Sequences:

>Translated_69_residues
MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAADHRLAELITGKLYDRIPKEIWKYVR
>Mature_68_residues
AKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAADHRLAELITGKLYDRIPKEIWKYVR

Specific function: Down-regulates hemolysin production and can also stimulate transposition events in vivo. May bind DNA and influence DNA topology in response to environmental stimuli [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hha/ymoA/cnu family [H]

Homologues:

Organism=Escherichia coli, GI1786665, Length=66, Percent_Identity=53.030303030303, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007985 [H]

Pfam domain/function: PF05321 HHA [H]

EC number: NA

Molecular weight: Translated: 8293; Mature: 8161

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAADHRLAELITGKLYDRI
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKEIWKYVR
HHHHHHHCC
>Mature Secondary Structure 
AKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAADHRLAELITGKLYDRI
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKEIWKYVR
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]