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The map label for this gene is tetD

Identifier: 218692840

GI number: 218692840

Start: 42340

End: 42756

Strand: Reverse

Name: tetD

Synonym: p1ECUMN_0052

Alternate gene names: 218692840

Gene position: 42756-42340 (Counterclockwise)

Preceding gene: 218692842

Following gene: 218692836

Centisome position: 34.96

GC content: 35.97

Gene sequence:

>417_bases
ATGTATATTGAACAGCATTCTCGCTATCAAAATAAAGCTAATAACATCCAATTAAGATATGATGATAAGCAGTTTCATAC
AACGGTTATCAAAGATGTTCTATTATGGATTGAACATAATTTAGATCAGTCTTTACTGCTTGATGATGTGGCGAATAAAG
CGGGTTATACCAAGTGGTATTTTCAGCGGCTGTTCAAAAAAGTAACAGGGGTCACACTGGCTAGCTATATTCGTGCTCGT
CGTTTGACGAAAGCGGCTGTTGAGTTGAGGTTGACGAAAAAAACTATCCTTGAGATCGCATTAAAATATCAATTTGATTC
CCAACAATCTTTTACACGTCGATTTAAGTACATTTTTAAGGTTACACCAAGTTATTATCGGCGTAATAAATTATGGGAAT
TGGAGGCAATGCACTGA

Upstream 100 bases:

>100_bases
TTTTATTTTCCATGATAGATTTAAAATAACATACCGTCAGTATGTTTATGGTATCATGATGATGTGGTCGTGACAATCTT
AAGAACATTTAGGTTATTTT

Downstream 100 bases:

>100_bases
GAGATCCCCTCATAATTTCCCCAAAGCGTAACCATGTGTGAATAAATTTTGAGCTAGTAGGGTTGCAGCCACGAGTAAGT
CTTCCCTTGTTATTGTGTAG

Product: transcriptionnal regulator involved in tetracycline resistance

Products: NA

Alternate protein names: ORFR [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKWYFQRLFKKVTGVTLASYIRAR
RLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKYIFKVTPSYYRRNKLWELEAMH

Sequences:

>Translated_138_residues
MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKWYFQRLFKKVTGVTLASYIRAR
RLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKYIFKVTPSYYRRNKLWELEAMH
>Mature_138_residues
MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKWYFQRLFKKVTGVTLASYIRAR
RLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKYIFKVTPSYYRRNKLWELEAMH

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=104, Percent_Identity=60.5769230769231, Blast_Score=140, Evalue=4e-35,
Organism=Escherichia coli, GI1790497, Length=102, Percent_Identity=50.9803921568627, Blast_Score=108, Evalue=9e-26,
Organism=Escherichia coli, GI87081928, Length=99, Percent_Identity=46.4646464646465, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 16775; Mature: 16775

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKWY
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
FQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKYIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VTPSYYRRNKLWELEAMH
CCHHHHHHCCCEEEECCC
>Mature Secondary Structure
MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKWY
CCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHH
FQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKYIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VTPSYYRRNKLWELEAMH
CCHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6094471; 6094472 [H]