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The map label for this gene is yjjN [H]

Identifier: 218692744

GI number: 218692744

Start: 5162732

End: 5163754

Strand: Direct

Name: yjjN [H]

Synonym: ECED1_5226

Alternate gene names: 218692744

Gene position: 5162732-5163754 (Clockwise)

Preceding gene: 218692742

Following gene: 218692751

Centisome position: 99.1

GC content: 50.34

Gene sequence:

>1023_bases
ATGTCCACAATGAAAGTATTAATTTGTCAGGAAATAAAGAATTTAGTATGGGAAGTCCGGGAAAGACCGGTGCCAGGCGA
TAATGAAGCATTAATTAAAATTAAAACTGTCGGGATTTGCGGTACAGATATTCATGCCTGGGCGGGCAATCAGCCATTTT
TCAGTTATCCACGCGTTTTAGGCCATGAAATATGTGGGGAGATTATTGAATCAGGAAAAAACATTCACAATTTTAATATC
GGACAGCAAGTTGCGGTAATTCCGTATATTTCTTGTCAGCAATGCCCGGCGTGTAAAAGCGGTCGTACCAATTGCTGTGA
AAAAATTTCAGTCATTGGCGTGCATCAGGATGGCGGTTTTAGTGAGTATTTGAGCGTGCCGGTGGCGAACATTTTGCCCG
CAGACGGTATTGACCCGCAGGCGGCAGCATTGATTGAACCTTTCGCTATTAGCGCTCATGCGGTGCGTCGCGCAGCCATT
GCTCCCGGCGAGCAGGTGCTGGTGGTCGGGGCGGGGCCAATCGGTCTGGGCGCGGCGGCAATCGCTAAAGCCGATGGCGC
ACAGGTGGTGGTGGCGGATACCAGTCCGGCGCGCCGTGAACATGTAGCAACGCGTCTGGAATTACCTGTTCTGGACCCGT
CAGCCGAAGATTTTGACGCGCAGCTGCGGGTGCAGTTTGGTGGTTCGCTGGCGCAGAAAGTGATTGACGCGACAGGTAAT
CAACATGCGATGAATAACACCGTAAATCTGATTCGTCACGGCGGCACGGTGGTATTTGTCGGCCTGTTTAAAGGTGAGTT
GCAGTTCTCCGATCCGGAATTCCATAAAAAAGAAACGACGATGATGGGCAGCCGCAACGCCACGCCGGAAGATTTCGCTA
AAGTCGGTCTATTGATGGCGGAAGGGAAAATCACTGCCGACATGATGTTAACCCATCGCTATCCGTTCGCCACGCTGGCA
GAAACCTACGAGCGCGATGTGATTAACAATCGTGAGTTGATTAAGGGCGTAATTACTTTCTGA

Upstream 100 bases:

>100_bases
ATTTTTATGCGCGATCATCCGCATATTTTATGGGTAAATTCAGGCGCTCTTATAAATTCGACGATATCTGAAAGTCATAA
AATAAAAGGAGCGGTGAATC

Downstream 100 bases:

>100_bases
TAAGGCGAGATTATTCAAGTTGCCATGCAGCGTCCGGGGAAGTGTTGGGCGCTGTTTTTTTGTTTCTTAATAATGTGTTG
TAAGCCGGAGAAGGCGTGTA

Product: putative oxidoreductase, Zn-dependent and NAD(P)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSTMKVLICQEIKNLVWEVRERPVPGDNEALIKIKTVGICGTDIHAWAGNQPFFSYPRVLGHEICGEIIESGKNIHNFNI
GQQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRVQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGLLMAEGKITADMMLTHRYPFATLA
ETYERDVINNRELIKGVITF

Sequences:

>Translated_340_residues
MSTMKVLICQEIKNLVWEVRERPVPGDNEALIKIKTVGICGTDIHAWAGNQPFFSYPRVLGHEICGEIIESGKNIHNFNI
GQQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRVQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGLLMAEGKITADMMLTHRYPFATLA
ETYERDVINNRELIKGVITF
>Mature_339_residues
STMKVLICQEIKNLVWEVRERPVPGDNEALIKIKTVGICGTDIHAWAGNQPFFSYPRVLGHEICGEIIESGKNIHNFNIG
QQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIA
PGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRVQFGGSLAQKVIDATGNQ
HAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGLLMAEGKITADMMLTHRYPFATLAE
TYERDVINNRELIKGVITF

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=319, Percent_Identity=31.3479623824451, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI4501929, Length=393, Percent_Identity=25.4452926208651, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI34577061, Length=393, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI71743840, Length=383, Percent_Identity=24.0208877284595, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI262073058, Length=355, Percent_Identity=24.2253521126761, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI226510992, Length=340, Percent_Identity=93.2352941176471, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1787863, Length=345, Percent_Identity=31.304347826087, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790045, Length=332, Percent_Identity=29.8192771084337, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788073, Length=332, Percent_Identity=29.2168674698795, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788407, Length=314, Percent_Identity=28.6624203821656, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788075, Length=340, Percent_Identity=27.0588235294118, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790718, Length=307, Percent_Identity=30.6188925081433, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082125, Length=319, Percent_Identity=27.5862068965517, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786825, Length=371, Percent_Identity=26.9541778975741, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081918, Length=312, Percent_Identity=28.2051282051282, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786518, Length=261, Percent_Identity=29.1187739463602, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=327, Percent_Identity=29.3577981651376, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17562878, Length=335, Percent_Identity=28.955223880597, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988145, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562584, Length=277, Percent_Identity=30.6859205776173, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562582, Length=327, Percent_Identity=28.7461773700306, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=354, Percent_Identity=24.8587570621469, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=356, Percent_Identity=24.438202247191, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565904, Length=349, Percent_Identity=25.214899713467, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=336, Percent_Identity=27.3809523809524, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319257, Length=359, Percent_Identity=28.9693593314763, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319955, Length=336, Percent_Identity=27.0833333333333, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323099, Length=326, Percent_Identity=29.7546012269939, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6323961, Length=343, Percent_Identity=30.6122448979592, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=321, Percent_Identity=26.1682242990654, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=251, Percent_Identity=31.4741035856574, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=316, Percent_Identity=30.0632911392405, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=328, Percent_Identity=27.4390243902439, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=349, Percent_Identity=23.7822349570201, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323980, Length=185, Percent_Identity=31.8918918918919, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319949, Length=252, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17737897, Length=324, Percent_Identity=30.8641975308642, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17137530, Length=321, Percent_Identity=29.595015576324, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17737895, Length=387, Percent_Identity=26.3565891472868, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45550770, Length=203, Percent_Identity=30.5418719211823, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45551930, Length=203, Percent_Identity=30.5418719211823, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221457811, Length=203, Percent_Identity=30.5418719211823, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36639; Mature: 36507

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMKVLICQEIKNLVWEVRERPVPGDNEALIKIKTVGICGTDIHAWAGNQPFFSYPRVL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEECCCCCCCHHHHHHH
GHEICGEIIESGKNIHNFNIGQQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRVQFGGSLAQKVIDATGN
HCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGLLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHCCCCCCCCHHHHHHHCEEEE
EGKITADMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
STMKVLICQEIKNLVWEVRERPVPGDNEALIKIKTVGICGTDIHAWAGNQPFFSYPRVL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCEECCCCCCCHHHHHHH
GHEICGEIIESGKNIHNFNIGQQVAVIPYISCQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDFDAQLRVQFGGSLAQKVIDATGN
HCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGLLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHCCCCCCCCHHHHHHHCEEEE
EGKITADMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]