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The map label for this gene is idnR [H]

Identifier: 218692651

GI number: 218692651

Start: 5059373

End: 5060371

Strand: Reverse

Name: idnR [H]

Synonym: ECED1_5117

Alternate gene names: 218692651

Gene position: 5060371-5059373 (Counterclockwise)

Preceding gene: 218692652

Following gene: 218692650

Centisome position: 97.14

GC content: 46.85

Gene sequence:

>999_bases
ATGCGCAATCACAGAATTTCTTTACAGGATATCGCTACGCTGGCTGGCGTAACAAAAATGACCGTGAGTCGTTATATCCG
CTCGCCGAAAAAGGTGGCAAAGGAAACAGGCGAGCGCATCGCCAAAATTATGGAAGAGATCAATTATATCCCTAATCGCG
CTCCCGGCATGTTGTTGAATGCACAAAGTTATACCCTCGGTATCTTGATTCCGTCATTTCAAAATCAACTCTTCGCTGAC
ATTCTCGCGGGAATAGAATCCGTCACCTCTGTGCATAATTATCAGACCCTTATTGCTAATTACAATTACAATCGCGATTC
CGAAGAAGAGTCGGTGATTAACCTGCTCTCTTATAACATTGACGGGATTATTCTTTCGGAAAAATATCACACCATCAGGA
CGGTGAAATTTCTGCGTTCAGCCACCATTCCGGTCGTGGAATTGATGGATGTACAGGGAGAACGGCTGGATATGGAGGTC
GGTTTTGATAATCGGCAGGCTGCTTTTGACATGGTGTGTACCATGCTGGATAAGCGAGTCAGGCGCAAAATTCTGTATCT
CGGTTCCAAAGATGACACCCGCGATGAACAGCGTTATCAGGGGTATTGCGATGCGATGATGCTGCATAATCTTTCCCCAT
TACGCATGAATCCACGCGCCATCTCATCCATTCATTTAGGAATGCAGTTAATGCGTGATGCCCTTAGCGCAAACCCGGAT
TTAGACGGTGTATTTTGCACCAATGACGATATTGCGATGGGTGCGCTTCTGCTGTGCCGCGAGCGAAACCTCGCCGTGCC
AGAACAAATTTCCATTGCGGGTTTTCATGGGCTGGAGATTGGCAGGCAAATGATCCCAAGCCTCGCCAGCGTAATTACTC
CCCGTTTTGATATTGGTCGGATGGCCGCCCAAATGTTGCTGAGCAAAATTAAGAATAACGATCACAACCACAACACTGTT
GACCTCGGGTATCAGATTTATCACGGTAACACGCTTTAG

Upstream 100 bases:

>100_bases
GGGCGTGTTAGCCATTAACGCCGTATTGCACTGAAAGAATAAAATATTGTGATGTAGTTTCGGGGGAAGATTGAAGATTC
CCCCGACGTTGGGAGAAGTT

Downstream 100 bases:

>100_bases
GTTATTTTCTCTGCATTACACATATTCTCTTTGCCGGACGTTGCCTATACTCCAGGCAGGAAACTGGAGGAAATCTCATG
AGCGAACCCCTGTTAATTGC

Product: DNA-binding transcriptional repressor, 5-gluconate-binding

Products: NA

Alternate protein names: L-idonate regulatory protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSVHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLDKRVRRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYHGNTL

Sequences:

>Translated_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSVHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLDKRVRRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYHGNTL
>Mature_332_residues
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFAD
ILAGIESVTSVHNYQTLIANYNYNRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
GFDNRQAAFDMVCTMLDKRVRRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTV
DLGYQIYHGNTL

Specific function: Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=98.7951807228916, Blast_Score=678, Evalue=0.0,
Organism=Escherichia coli, GI48994940, Length=332, Percent_Identity=46.0843373493976, Blast_Score=303, Evalue=7e-84,
Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=26.517571884984, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789068, Length=295, Percent_Identity=25.0847457627119, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=25.974025974026, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788474, Length=312, Percent_Identity=26.2820512820513, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789202, Length=315, Percent_Identity=26.031746031746, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787948, Length=320, Percent_Identity=24.375, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=25.0746268656716, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786268, Length=284, Percent_Identity=26.056338028169, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786540, Length=291, Percent_Identity=22.680412371134, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=20.3125, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790689, Length=314, Percent_Identity=21.9745222929936, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37542; Mature: 37542

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AQSYTLGILIPSFQNQLFADILAGIESVTSVHNYQTLIANYNYNRDSEEESVINLLSYNI
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLDKRV
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
HHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
MAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
HHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC
>Mature Secondary Structure
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLN
CCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
AQSYTLGILIPSFQNQLFADILAGIESVTSVHNYQTLIANYNYNRDSEEESVINLLSYNI
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHCC
DGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLDKRV
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
RRKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPD
HHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
LDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
MAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
HHHHHHHHHHHCCCCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]