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The map label for this gene is treC [H]

Identifier: 218692627

GI number: 218692627

Start: 5030427

End: 5032082

Strand: Reverse

Name: treC [H]

Synonym: ECED1_5094

Alternate gene names: 218692627

Gene position: 5032082-5030427 (Counterclockwise)

Preceding gene: 218692628

Following gene: 218692626

Centisome position: 96.59

GC content: 52.72

Gene sequence:

>1656_bases
ATGACTCATCTTCCCCACTGGTGGCAAAACGGCGTTATCTACCAGATTTATCCAAAGAGTTTTCAGGACACCACGGGTAG
CGGCACCGGCGATTTACGTGGCGTTATCCAACGCCTGGACTATCTGCATAAACTGGGCGTTGATGCCATCTGGCTAACCC
CCTTTTATGTCTCTCCCCAGGTCGATAACGGTTACGACGTAGCGAATTATACGGCGATTGATCCCACCTATGGCACGCTG
GACGATTTTGACGAACTGGTGACACAGGCAAAATCGCGTGGGATTCGTATCATTCTCGATATGGTGTTTAACCATACCTC
TACCCAACATGCCTGGTTTCGCGAGGCGCTGAACAAAGAAAGCCCTTACCGCCAGTTTTATATCTGGCGCGATGGAGAAC
CAGAAACGCCACCGAACAACTGGCGTTCAAAATTCGGTGGTAGTGCGTGGCGCTGGCATGCAGAAAGCGAACAGTACTAT
TTGCATCTCTTTGCACCAGAACAGGCGGATCTCAACTGGGAGAATCCAGCGGTACGCGCAGAGCTGAAAAAAGTCTGTGA
GTTCTGGGCCGATCGTGGGGTCGACGGGTTGCGCCTGGATGTGGTGAATCTGATCTCCAAAGACCCGCGTTACCCTGAAG
ACCTGGATGGCGATGGGCGTCGCTTCTATACCGACGGGCCACGAGCACACGAGTTTTTGCACGAGATGAACCGCGATGTG
TTTACGCCACGCGGGTTAATGACCGTAGGTGAAATGTCCTCCACCAGCCTTGAGCATTGCCAGCGATACGCGGCACTGAC
AGGCAGTGAATTGTCGATGACCTTTAATTTTCATCACCTGAAGGTCGATTATCCCGGTGGTGAAAAATGGACGCTGGCTA
AACCTGACTTTGTGGCGTTGAAAACATTGTTCCGCCACTGGCAACAAGGAATGCACAACGTGGCATGGAATGCCTTGTTC
TGGTGTAACCACGATCAGCCGCGCATTGTTTCTCGCTTTGGTGATGAAGGTGAATACCGCGTGCCTGCGGCAAAAATGCT
GGCGATGGTGCTGCATGGCATGCAGGGAACGCCGTATATCTACCAGGGCGAAGAGATTGGCATGACCAACCCACATTTCA
CGCGCATTACTGACTATCGCGACGTGGAGAGCCTCAATATGTTTGCCGAGCTGCGCAACGATGGGCGTGATGCCGACGAG
TTATTGACAATCCTCGCCAGTAAATCCCGTGACAACAGTCGCACACCCATGCAATGGACCAACGGCGATAATGCCGGGTT
TACGGCTGGCGAACCGTGGATTGGCCTGGGCGATAACTATCAGGAAATCAACGTAGAAGCAGCGCTGGCCGATGAGTCCT
CGGTGTTTTACACCTACCAAAAGTTAATCGCACTGCGTAAGCAAGAAGCCGTCCTGACATGGGGCGATTACCAGGATCTG
CTGCCAAACAGCCCTGTATTGTGGTGCTATCGCCGTGAATGGAAGGGGCAAACCTTGCTGGTCATTGCCAACCTTAGCCG
TGAGATCCAACCCTGGCAACCAGGGCAAATGCGCGGCAACTGGCAGCTTGTGATGCATAACTACGAAGAAGCCTCACCAC
AACCCTGCGCCATGACTTTACGGCCTTTTGAGGCTGTCTGGTTGTTACAAAAGTAA

Upstream 100 bases:

>100_bases
TCGTTTATCTATCAGCGGAAATACCGCCTGGGCACGCTGGACATTGTTTAATTTTCTTCGGGGCGCAATTGCGCCCCCTC
GCATTTGCAGGAATAACGTA

Downstream 100 bases:

>100_bases
ATCTTCGCTAAGCCCCGGTAATGCCGGTCATTCCGGGGTTTTGTCTGTCAGCATGTTGTTTTTGTTGATTTTTCAACCAG
CAAATTCATTAAAAAATTTA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MTHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRYPEDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLTILASKSRDNSRTPMQWTNGDNAGFTAGEPWIGLGDNYQEINVEAALADESSVFYTYQKLIALRKQEAVLTWGDYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWLLQK

Sequences:

>Translated_551_residues
MTHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRYPEDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLTILASKSRDNSRTPMQWTNGDNAGFTAGEPWIGLGDNYQEINVEAALADESSVFYTYQKLIALRKQEAVLTWGDYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWLLQK
>Mature_550_residues
THLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLD
DFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYL
HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRYPEDLDGDGRRFYTDGPRAHEFLHEMNRDVF
TPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFW
CNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADEL
LTILASKSRDNSRTPMQWTNGDNAGFTAGEPWIGLGDNYQEINVEAALADESSVFYTYQKLIALRKQEAVLTWGDYQDLL
PNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWLLQK

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=522, Percent_Identity=29.5019157088123, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI61744479, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI65506891, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI61744481, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI61744475, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744483, Length=108, Percent_Identity=36.1111111111111, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI61744477, Length=107, Percent_Identity=36.4485981308411, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=98.0036297640653, Blast_Score=1135, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=188, Percent_Identity=31.3829787234043, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789995, Length=137, Percent_Identity=32.8467153284672, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=488, Percent_Identity=26.2295081967213, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565753, Length=526, Percent_Identity=22.6235741444867, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=36.2847222222222, Blast_Score=357, Evalue=3e-99,
Organism=Saccharomyces cerevisiae, GI6322245, Length=582, Percent_Identity=35.7388316151203, Blast_Score=354, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=36.6319444444444, Blast_Score=345, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=36.6319444444444, Blast_Score=344, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=36.6319444444444, Blast_Score=344, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=34.8122866894198, Blast_Score=329, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=34.641638225256, Blast_Score=328, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24583745, Length=537, Percent_Identity=36.6852886405959, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI221330053, Length=499, Percent_Identity=37.2745490981964, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24583747, Length=545, Percent_Identity=36.1467889908257, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24583749, Length=545, Percent_Identity=36.1467889908257, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24586597, Length=532, Percent_Identity=34.7744360902256, Blast_Score=285, Evalue=7e-77,
Organism=Drosophila melanogaster, GI24586599, Length=580, Percent_Identity=31.8965517241379, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24586587, Length=503, Percent_Identity=33.7972166998012, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24586593, Length=520, Percent_Identity=32.8846153846154, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI45549022, Length=541, Percent_Identity=33.826247689464, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24586589, Length=536, Percent_Identity=33.3955223880597, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586591, Length=494, Percent_Identity=32.3886639676113, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI281360393, Length=466, Percent_Identity=30.68669527897, Blast_Score=203, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63859; Mature: 63728

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDPRYPEDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLTILASKSRDNSRTPMQWT
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQEINVEAALADESSVFYTYQKLIALRKQEAVLTWGDYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCHHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTL
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
RPFEAVWLLQK
CCCEEEEEECC
>Mature Secondary Structure 
THLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQ
CCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKE
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHHCCC
SPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYYLHLFAPEQADLNWENPAVRA
CCCEEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCHHHH
ELKKVCEFWADRGVDGLRLDVVNLISKDPRYPEDLDGDGRRFYTDGPRAHEFLHEMNRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCC
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVAL
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCHHHH
KTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADELLTILASKSRDNSRTPMQWT
EECCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEC
NGDNAGFTAGEPWIGLGDNYQEINVEAALADESSVFYTYQKLIALRKQEAVLTWGDYQDL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEECCHHHH
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTL
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEE
RPFEAVWLLQK
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]