BacMap

Definition	Escherichia coli ED1a chromosome, complete genome.
Accession	NC_011745
Length	5,209,548

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The map label for this gene is fabG [H]

Identifier: 218692594

GI number: 218692594

Start: 4992609

End: 4993400

Strand: Reverse

Name: fabG [H]

Synonym: ECED1_5061

Alternate gene names: 218692594

Gene position: 4993400-4992609 (Counterclockwise)

Preceding gene: 218692596

Following gene: 218692593

Centisome position: 95.85

GC content: 53.16

Gene sequence:

>792_bases
ATGAAATCCACTCGTCCTGTTGCCGTGATTACCGGAGCCGCACGTGGTATTGGAAAGGGCTGTGCGCTGGAGCTTGCGCG
TGGCGGATTTAATCTGCTGATTAATGATCGTCCGGATGCGGATAGCGTAGAAAAATTACATGCCACACAACAAGAATGTC
TGGCGGAAGGCGTGGAAGTGATTTGCTTCCCTGCTGATGTGGGCGATCTCTCCCTGCATGAAGAGATGCTCGACGCAGCG
CAAAACCAGTGGGGACGTCTGGACTGCCTGCTCAACAACGCAGGCATTTCAGTGAAAAAACGCGGTGACCTTCTCGACCT
CGAACCAGACAGCTTCGACCAAAATATTGCCATTAACACCCGCGCACCGTTCTTCCTTGCTCAGGCATTCAGTAAGCGCT
TACTGGCACAGCCGAAACCGGAAGCAGAACTGCCGCACCGCTCGATTATTTTTGTCAGTTCCATCAACGCCATCATGCTG
GCGATGAATCGCGGCGAATATACCATTGCCAAAACTGCCGTCTCTGCCGCTGCTCGTCTGTTTGCTGCTCGCCTTTGTAA
TGAACAAATTGGCGTATATGAAGTGCGTCCTGGTCTCATCAAAACCGATATGACTATTCCGGCAACGGCCTATTACGACG
AACTGATTGCCAAAGGTCTGGTGCCGTGGGGACGTTGGGGTTATCCGGCTGATATTGCTTCCACTGTCCGCGCGATGGCG
GAAGGTAAACTGATTTACACCTGTGGTCAGGCGGTCGCCATCGACGGCGGCTTAAGTATGCCGCGCTTCTGA

Upstream 100 bases:

>100_bases
GCCATCGCATATCAACCAACTAGATGGTTGATCTTTTTATCCTCCAGTCGCAAGCTAATCATCACTAAGGAAACAAAATT
CAAAAAAAGAGAGCTATTGT

Downstream 100 bases:

>100_bases
GGCTGAATCATGAGAGATCTGTTACAACGCCCGGATTTATTCAGTATCAATACCGCGACACTGGGCTATAAAACGCCGCT
ACCCGCCATTATTGATGCCT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVEKLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF

Sequences:

>Translated_263_residues
MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVEKLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF
>Mature_263_residues
MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVEKLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAA
QNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
EGKLIYTCGQAVAIDGGLSMPRF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=31.6582914572864, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=29.2490118577075, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=25.6916996047431, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=27.5193798449612, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=25.2918287937743, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=29.4117647058824, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788459, Length=262, Percent_Identity=29.3893129770992, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082100, Length=273, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=31.3653136531365, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=28.4671532846715, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.1115241635688, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=27.4074074074074, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.2592592592593, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=27.8195488721804, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.2267657992565, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=30.5454545454545, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=30.2583025830258, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=28, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=30.3370786516854, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=25, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=264, Percent_Identity=26.5151515151515, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.1954887218045, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=29.0566037735849, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=30.7392996108949, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=28.7272727272727, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=26.2548262548263, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=26.9090909090909, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.3408239700375, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=26.3779527559055, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=273, Percent_Identity=26.7399267399267, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=266, Percent_Identity=24.812030075188, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=25.78125, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=27.4809160305344, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=27.34375, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=27.6264591439689, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=28.2945736434109, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=25.2918287937743, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28465; Mature: 28465

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVEKLHATQQECLAEGVEV
CCCCCCEEEEECCCCCCCCCHHEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEE
ICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINT
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEC
RAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIMLAMNRGEYTIAKTAVSAAARL
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHH
FAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
HHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EGKLIYTCGQAVAIDGGLSMPRF
CCCEEEECCCEEEECCCCCCCCC
>Mature Secondary Structure
MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVEKLHATQQECLAEGVEV
CCCCCCEEEEECCCCCCCCCHHEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEE
ICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRGDLLDLEPDSFDQNIAINT
EEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCEEECCCCCCCCCEEEEC
RAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIMLAMNRGEYTIAKTAVSAAARL
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEHHHHHHHHHHHH
FAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAKGLVPWGRWGYPADIASTVRAMA
HHHHHHCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
EGKLIYTCGQAVAIDGGLSMPRF
CCCEEEECCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA