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The map label for this gene is irgA [H]

Identifier: 218692567

GI number: 218692567

Start: 4967580

End: 4968599

Strand: Reverse

Name: irgA [H]

Synonym: ECED1_5034

Alternate gene names: 218692567

Gene position: 4968599-4967580 (Counterclockwise)

Preceding gene: 218692568

Following gene: 218692566

Centisome position: 95.37

GC content: 51.27

Gene sequence:

>1020_bases
GTGGGGGGCGAGTTTCAGAGCTCGTCCATGAAAGACGGAGTTGTCCTTGCCAGCACAGGTGAAACTTTCCGGCAGAAAAG
CTGGTCGGTATTTGCTGAGGATGAGTGGCATCTCACGGATGCACTTGCGCTGACTGCGGGCAGCCGCTATGAACATCATG
AGCAATTCGGGGGACACTTCAGTCCGCGTGCATATCTGGTCTGGGATGTGGCAGATGCCTGGACGCTGAAAGGCGGTGTG
ACCACGGGATATAAGGCACCCAGAATGGGACAGCTACATAAAGGGATTAGTGGTGTGTCCGGGCAGGGAAAAACAAATCT
ACTTGGTAACCCCGACCTGAAGCCGGAAGAGAGCGTCAGTTATGAGGCTGGGGTGTATTACGATAACCCCGCCGGTCTGA
ATGCCAATGTCACAAGTTTTATGACTGACTTCTCCAACAAGATTGTCTCTTATTCCATAAATGATAACACCAATAGCTAT
GTAAACAGCGGAAAGGCCCGGTTGCACGGTGTGGAATTTGCCGGCACATTGCCGCTGTGGTCAGAGGATGTCACGCTGTC
ACTGAATTACACCTGGACCCGAAGTGAACAACGTGATGGTGATAACAAAGGTGCGCCGCTGAGTTATACCCCTGAACACA
TGGTGAATGCGAAACTGAACTGGCAGATCACCGAAGAGGTGGCATCATGGCTGGGTGCCCGTTACCGCGGGAAAACACCA
CGTTTCACCCAGAATTATTCGTCACTGAGCGCTGTACAGAAGAAAGTGTATGATGAGAAAGGAGAATACCTGAAAGCCTG
GACAGTGGTGGATGCAGGTCTGTCGTGGAAGATGACGGATGCCCTGACGCTGAATGCTGCGGTGAATAACCTGCTCAACA
AGGATTACAGTGACGTGAGCCTGTACAGTGCCGGTAAGAGTACGCTGTATGCCGGTGATTACTTCCAGACGGGATCATCA
ACAACAGGATATGTGATACCTGAGCGAAATTACTGGATGTCGCTGAACTATCAGTTCTGA

Upstream 100 bases:

>100_bases
TTACAGAGTTCTCGGTACAGGGGAAAAGTGGTACCTGTCGCCAGTTCTCCGATCTGTTTAACCGGGAAATTATCTTCAGG
GAGAATCTCATCTGGTTACG

Downstream 100 bases:

>100_bases
TAATAACAAAACGCTATCACTGACGGTAGAATACGTTGCCACTGCAACTCCTGGCGGAACAGTGGCAACGTATTAGGTTA
AGTGCATTTCCGATCCGCTA

Product: Iha adhesin (partial)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGV
TTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTSFMTDFSNKIVSYSINDNTNSY
VNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTP
RFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSS
TTGYVIPERNYWMSLNYQF

Sequences:

>Translated_339_residues
MGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGV
TTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTSFMTDFSNKIVSYSINDNTNSY
VNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTP
RFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSS
TTGYVIPERNYWMSLNYQF
>Mature_338_residues
GGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVT
TGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAGLNANVTSFMTDFSNKIVSYSINDNTNSYV
NSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTPR
FTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSST
TGYVIPERNYWMSLNYQF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=350, Percent_Identity=33.7142857142857, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786798, Length=346, Percent_Identity=29.1907514450867, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790405, Length=274, Percent_Identity=27.007299270073, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 37650; Mature: 37519

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHF
CCCCCCCCCCCCCEEEEECCHHHHHCCCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCC
SPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVS
CCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
YEAGVYYDNPAGLNANVTSFMTDFSNKIVSYSINDNTNSYVNSGKARLHGVEFAGTLPLW
EECCEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEEEEEEEECCCCCC
SEDVTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTP
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCC
RFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVS
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCCCEE
LYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
EEECCCCEEEECCEEECCCCCCEEEEECCCEEEEEEECC
>Mature Secondary Structure 
GGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHF
CCCCCCCCCCCCEEEEECCHHHHHCCCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCC
SPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVS
CCCEEEEEECCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
YEAGVYYDNPAGLNANVTSFMTDFSNKIVSYSINDNTNSYVNSGKARLHGVEFAGTLPLW
EECCEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHCCCCEEEEEEEEECCCCCC
SEDVTLSLNYTWTRSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTP
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCC
RFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKDYSDVS
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEEEEHHHHHHHHHCCCCCCEE
LYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
EEECCCCEEEECCEEECCCCCCEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]