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The map label for this gene is dgoR [H]

Identifier: 218691983

GI number: 218691983

Start: 4311982

End: 4312671

Strand: Reverse

Name: dgoR [H]

Synonym: ECED1_4386

Alternate gene names: 218691983

Gene position: 4312671-4311982 (Counterclockwise)

Preceding gene: 218691985

Following gene: 218691982

Centisome position: 82.78

GC content: 55.07

Gene sequence:

>690_bases
ATGACTCTCAATAAAACCGATCGCATCGTTATTACGCTGGGTAGACAGATCGTTCACGGCAAATACGTGCCAGGCTCGCC
GCTTCCGGCTGAGGCAGAACTCTGTGAGGAGTTTGCAACCTCGCGCAACATCATCCGTGAGGTATTTCGTTCGCTGATGG
CGAAGCGGCTGATTGAAATGAAACGTTATCGCGGGGCGTTTGTGGCTCCGCGTAACCAGTGGAATTACCTCGACACTGAC
GTACTGCAATGGGTGCTGGAAAACGACTACGACCCACGGCTTATCAGTGCAATGAGCGAAGTGCGAAATCTGGTGGAACC
GGCGATTGCCCGTTGGGCAGCAGAACGCGCGACCTCCAGCGATCTGGCGCAGATTGAATCGGCGCTGAACGAGATGATTG
CTAACAATCAGGACCGCGAAGCGTTTAACGAAGCGGATATTCGCTACCACGAGGCGGTGCTGCAGTCGGTGCATAACCCG
GTGTTACAGCAACTGAGCATTGCGATCAGTTCGCTGCAGCGGGCGGTTTTTGAACGAACCTGGATGGGCGATGAGGCCAA
CATGCCGCAAACGCTCCAGGAACATAAGGCGCTGTTCGATGCGATAAGGCATCAGGACGGCGATGCGGCAGAGCAGGCGG
CGCTTACCATGATCGCCAGCTCGACACGAAGGTTAAAGGAAATCACATGA

Upstream 100 bases:

>100_bases
CAGCAAACGCGAACGTCATCACGCTGGTACTACAAAATTACCGCGTTATGCATCGATCGGGGTAAAGTAGAGAAGAACAT
ACAGAGCACAAGGACTCTCC

Downstream 100 bases:

>100_bases
CAGCTCGCTACATCGCAATTGACTGGGGATCGACCAATCTGCGCGCCTGGCTTTATCAGGGCGACCACTGCCTGGACAGC
AGGCAATCAGAAGCAGGCGT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTLNKTDRIVITLGRQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTD
VLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT

Sequences:

>Translated_229_residues
MTLNKTDRIVITLGRQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTD
VLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT
>Mature_228_residues
TLNKTDRIVITLGRQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDV
LQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNPV
LQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=229, Percent_Identity=99.5633187772926, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI48994961, Length=213, Percent_Identity=30.9859154929577, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790032, Length=212, Percent_Identity=28.3018867924528, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790780, Length=234, Percent_Identity=26.4957264957265, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787821, Length=222, Percent_Identity=28.3783783783784, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26108; Mature: 25977

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNKTDRIVITLGRQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEM
CCCCCCCCEEEHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSS
HHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNPVLQQLSIAISSLQRAVFERT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT
HCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLNKTDRIVITLGRQIVHGKYVPGSPLPAEAELCEEFATSRNIIREVFRSLMAKRLIEM
CCCCCCCEEEHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSS
HHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNPVLQQLSIAISSLQRAVFERT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMIASSTRRLKEIT
HCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]