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The map label for this gene is dgoT [H]

Identifier: 218691979

GI number: 218691979

Start: 4307949

End: 4309241

Strand: Reverse

Name: dgoT [H]

Synonym: ECED1_4382

Alternate gene names: 218691979

Gene position: 4309241-4307949 (Counterclockwise)

Preceding gene: 218691980

Following gene: 218691977

Centisome position: 82.72

GC content: 52.51

Gene sequence:

>1293_bases
ATGGATATTCCCGTTAATGCAGCAAAGCCGGGGCGTCGGCGTTATCTGACGCTGGTGATGATCTTTATTACGGTGGTCAT
TTGTTATGTTGACCGCGCTAACCTGGCCGTGGCTTCTGCCCATATTCAGGAAGAGTTTGGTATTACTAAAGCGCAAATGG
GCTATGTATTTTCGGCCTTCGCCTGGCTTTATACGCTATGTCAGATCCCCGGTGGTTGGTTTTTAGATCGCGTAGGCTCA
CGCGTGACTTATTTTATTGCGATATTTGGCTGGTCAGTGGCGACGTTATTCCAGGGCTTTGCCACGGGCTTAATGTCATT
AATTGGTCTGCGCGCGATAACCGGTATTTTCGAAGCGCCCGCGTTCCCGACCAATAACCGGATGGTAACCAGTTGGTTCC
CGGAACATGAACGTGCTTCTGCCGTTGGTTTTTATACGTCTGGTCAGTTTGTCGGTCTGGCGTTTCTGACTCCGCTGCTG
ATCTGGATTCAGGAGATGTTGAGCTGGCACTGGGTGTTCATTGTCACCGGTGGTATCGGCATTATCTGGTCGCTGATTTG
GTTTAAGGTTTATCAGCCGCCGCGTCTGACCAAAGGCATCAGCAAAGCTGAACTGGATTACATTCGTGATGGCGGCGGTC
TGGTGGATGGCGATGCGCCGGTGAAAAAAGAGGCGCGTCAGCCGTTAACAGCCAAAGACTGGAAACTGGTGTTCCATCGT
AAACTGATCGGTGTCTATCTTGGGCAATTTGCGGTGGCTTCTACACTGTGGTTTTTCTTAACCTGGTTCCCGAACTATTT
AACCCAGGAAAAAGGAATCACGGCGCTGAAAGCAGGTTTTATGACCACGGTGCCATTCCTCGCGGCGTTTATTGGCGTCC
TGCTCTCTGGCTGGGTCGCGGATCTGCTGGTACGTAAGGGCTTTTCACTGGGCTTTGCGCGTAAAACGCCGATTATCTGC
GGCTTGCTGATCTCCACCTGCATTATGGGTGCGAACTACACCAACGATCCGATGATGATTATGTGCCTGATGGCGCTGGC
ATTCTTCGGCAACGGTTTTGCTTCGATAACCTGGTCGCTGGTCTCTTCTCTGGCACCGATGCGCCTGATTGGTTTAACCG
GCGGCGTGTTTAACTTTGCCGGTGGTCTGGGCGGCATCACTGTTCCGCTGGTGGTGGGGTACCTGGCGCAGGGTTACGGT
TTCGCACCTGCACTGGTTTATATCTCCGCCGTCGCGTTGATTGGCGCGCTCTCTTACATCCTGCTGGTGGGCGATGTGAA
GCGCGTTGGATAA

Upstream 100 bases:

>100_bases
TCATCGGGCACTAAAACAGCAATACAAAAATATAACCCTCTGTAAATTACAGGGCATGGTGAGCGGCTTCGCTATGCCCA
AAATCTGGAGAAAGCTCGCT

Downstream 100 bases:

>100_bases
TCTTTCAACTGTGGAATATGCGCCACTCCACTGCGCATAATCCACTTTCTTAAAGCCGGTGCGGTCAGGCATCGGCTTTT
TACTATCTTGCCGAAGAGTT

Product: D-galactonate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILLVGDVKRVG

Sequences:

>Translated_430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILLVGDVKRVG
>Mature_430_residues
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAQMGYVFSAFAWLYTLCQIPGGWFLDRVGS
RVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLL
IWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVADLLVRKGFSLGFARKTPIIC
GLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYG
FAPALVYISAVALIGALSYILLVGDVKRVG

Specific function: Intake of galactonate into the cell [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=420, Percent_Identity=25.4761904761905, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI9945322, Length=410, Percent_Identity=25.8536585365854, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI154350196, Length=412, Percent_Identity=24.0291262135922, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI21322234, Length=407, Percent_Identity=24.0786240786241, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI9966811, Length=408, Percent_Identity=24.0196078431373, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI148743791, Length=389, Percent_Identity=26.7352185089974, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI148728191, Length=309, Percent_Identity=27.1844660194175, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223718438, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI5031955, Length=259, Percent_Identity=24.7104247104247, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=99.5348837209302, Blast_Score=861, Evalue=0.0,
Organism=Escherichia coli, GI1789152, Length=435, Percent_Identity=42.7586206896552, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=40.9195402298851, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=29.1954022988506, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI2367193, Length=410, Percent_Identity=27.0731707317073, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788573, Length=437, Percent_Identity=23.5697940503432, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=21.7494089834515, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082404, Length=387, Percent_Identity=23.7726098191214, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=424, Percent_Identity=25, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=423, Percent_Identity=25.0591016548463, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71997452, Length=407, Percent_Identity=23.8329238329238, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=427, Percent_Identity=23.4192037470726, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=431, Percent_Identity=24.1299303944316, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=377, Percent_Identity=25.9946949602122, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=203, Percent_Identity=26.6009852216749, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=247, Percent_Identity=22.6720647773279, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=247, Percent_Identity=22.6720647773279, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=333, Percent_Identity=24.3243243243243, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550460, Length=318, Percent_Identity=25.1572327044025, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24648416, Length=409, Percent_Identity=25.6723716381418, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21356189, Length=409, Percent_Identity=25.6723716381418, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24655255, Length=285, Percent_Identity=25.6140350877193, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573299, Length=410, Percent_Identity=23.4146341463415, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24658658, Length=410, Percent_Identity=23.6585365853659, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655271, Length=408, Percent_Identity=23.0392156862745, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130135, Length=408, Percent_Identity=23.0392156862745, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130167, Length=439, Percent_Identity=23.6902050113895, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI62484226, Length=404, Percent_Identity=24.009900990099, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24639764, Length=334, Percent_Identity=24.8502994011976, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28573708, Length=342, Percent_Identity=21.9298245614035, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573707, Length=342, Percent_Identity=21.9298245614035, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19922400, Length=424, Percent_Identity=24.7641509433962, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24658674, Length=410, Percent_Identity=23.4146341463415, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24654215, Length=424, Percent_Identity=24.7641509433962, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24653727, Length=387, Percent_Identity=25.5813953488372, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550495, Length=406, Percent_Identity=22.1674876847291, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583789, Length=380, Percent_Identity=22.3684210526316, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580790, Length=373, Percent_Identity=25.4691689008043, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=22.9974160206718, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584153, Length=300, Percent_Identity=22, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920686, Length=390, Percent_Identity=22.0512820512821, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24658689, Length=409, Percent_Identity=24.2053789731051, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552797, Length=409, Percent_Identity=24.2053789731051, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129235, Length=273, Percent_Identity=24.1758241758242, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45550364, Length=220, Percent_Identity=23.1818181818182, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281361682, Length=346, Percent_Identity=22.2543352601156, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47090; Mature: 47090

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAQMGYVFSAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAP
HHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIG
CCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCHH
IIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYI
HHHCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLVGDVKRVG
HHHHHHHHCC
>Mature Secondary Structure
MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAQMGYVFSAF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAP
HHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIG
CCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCHH
IIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHR
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHH
KLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFIGVLLSGWVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
VSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYI
HHHCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLVGDVKRVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]