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The map label for this gene is frwB [H]

Identifier: 218691944

GI number: 218691944

Start: 4269718

End: 4270032

Strand: Reverse

Name: frwB [H]

Synonym: ECED1_4346

Alternate gene names: 218691944

Gene position: 4270032-4269718 (Counterclockwise)

Preceding gene: 218691945

Following gene: 218691943

Centisome position: 81.97

GC content: 41.59

Gene sequence:

>315_bases
ATGAATATTGTCTGTGTTGCCGCCTGTACGGCGGGTATTGCTCATACCTATATTGCTCGTGAAAAGTTAATCAAAGGAGC
AAAAGCTCTGGGCCATACCATTAAAGTTGAAACCCAGGGAACCATTGGTACAGAAAATGAATTACAGGCGGCAGATATCT
CTGCTGCTGACGTCGTGATTCTTGCTGTAGATGTGAAAATAAAAGGAGAAGAACGCTTCACCAATAAACGTATTGTGCGA
GTAAAGACAGAGATCGTCATTAAATCGCCCGTTCAATTTCTTGAAAAGGTCGAAAAATCACTGGGAAACAAATGA

Upstream 100 bases:

>100_bases
TCATAGAACAATTGTTAGTTGAGACGAGTCCGCAAAAAATCATTGATCTCTTTAGTCAGTATGCACAATCCGATGTCTGC
TAAATAACAGGAAGTATGTC

Downstream 100 bases:

>100_bases
TCCTTATACTGGAGGGATCTTAATATGAAAGAAAATAAAATTCCGGTTTCACAGGAAATTAAAAAACATTTATTAACCGG
CATCTCGTGGATGATACCCC

Product: putative phosphotransferase system, fructose-specific IIB subunit

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGTENELQAADISAADVVILAVDVKIKGEERFTNKRIVR
VKTEIVIKSPVQFLEKVEKSLGNK

Sequences:

>Translated_104_residues
MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGTENELQAADISAADVVILAVDVKIKGEERFTNKRIVR
VKTEIVIKSPVQFLEKVEKSLGNK
>Mature_104_residues
MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGTENELQAADISAADVVILAVDVKIKGEERFTNKRIVR
VKTEIVIKSPVQFLEKVEKSLGNK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=101, Percent_Identity=50.4950495049505, Blast_Score=99, Evalue=5e-23,
Organism=Escherichia coli, GI87082348, Length=99, Percent_Identity=42.4242424242424, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI1790390, Length=100, Percent_Identity=39, Blast_Score=77, Evalue=2e-16,
Organism=Escherichia coli, GI1786951, Length=71, Percent_Identity=50.7042253521127, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788492, Length=94, Percent_Identity=37.2340425531915, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI1788730, Length=102, Percent_Identity=30.3921568627451, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 11244; Mature: 11244

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGTENELQAADISAADVVI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEE
LAVDVKIKGEERFTNKRIVRVKTEIVIKSPVQFLEKVEKSLGNK
EEEEEEECCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGTENELQAADISAADVVI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEE
LAVDVKIKGEERFTNKRIVRVKTEIVIKSPVQFLEKVEKSLGNK
EEEEEEECCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]