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The map label for this gene is xylB [H]

Identifier: 218691853

GI number: 218691853

Start: 4169140

End: 4170594

Strand: Reverse

Name: xylB [H]

Synonym: ECED1_4249

Alternate gene names: 218691853

Gene position: 4170594-4169140 (Counterclockwise)

Preceding gene: 218691854

Following gene: 218691852

Centisome position: 80.06

GC content: 54.09

Gene sequence:

>1455_bases
ATGTATATCGGGATAGATCTTGGCACCTCGGGCGTAAAAGTTATTTTGCTCAACGAGCAGGGTGAGGTGGTTGCTGCGCA
AACGGAAAAGCTGACCGTTTCGCGCCCGCATCCACTCTGGTCGGAACAAGACCCGGAACAGTGGTGGCAGGCAACTGATC
GCGCAATGAAAGCTCTGGGCGTTCAGCATTCTCTGCAAGACGTTAAAGCATTAGGTATTGCCGGACAGATGCACGGTGCA
ACCTTACTGGATGCTCAGCAACGGGTGTTACGCCCTGCCATTTTGTGGAACGACGGGCGCTGTGCGCAAGAGTGCACTTT
GCTGGAAGCGCGAGTTCCGCAATCGCGGGTGATTACCGGCAACCTGATGATGCCCGGATTTACTGCGCCTAAATTGCTAT
GGGTTCAGCGGCATGAGCCGGAGATATTCCGTCAAATCGATAAGGTATTATTACCGAAAGATTACTTGCGTCTGCGTATG
ACGGGGGAGTTTGCCAGCGATATGTCTGACGCAGCTGGCACTATGTGGCTGGATGTCGCAAAGCGTGACTGGAGCGATCT
CATGCTGCAGGCTTGCCACTTATCTCGTGACCAGATGCCCGCATTATACGAAGGCAGCGAAATTACTGGTGCTTTGTTAC
CTGAAGTTGCGAAAGCGTGGGGTATGGCGGCGGTGCCAGTTATCGCAGGCGGTGGCGACAATGCAGCTGGTGCGGTTGGT
GTGGGAATGGTTGATGCTAATCAGGCAATGTTATCGCTGGGGACGTCGGGGGTCTATTTTGCTGTCAGCGAAGGGTTCTT
AAGCAAGCCAGAAAGCGCCGTACATAGCTTTTGCCATGCGTTACCGCAACGTTGGCATTTAATGTCTGTAATGCTGAGTG
CGGCTTCGTGTCTGGATTGGGCCGCGAAATTAACCGGCCTGAGCAATGTCCCTGCTTTAATCACTGCAGCTCAACAGGCT
GATGAAAGTGCCGAGCCAGTTTGGTTTCTGCCTTATCTTTCCGGCGAGCGTACACCACACAATAATCCCCAGGCGAAAGG
GGTTTTCTTTGGTTTGACTCATCAACATGGCCCCAATGAACTGGCGCGAGCAGTGCTGGAAGGCGTGGGTTATGCGCTGG
CAGATGGCATGGATGTCGTGCATGCCTGCGGCATTAAACCGCAAAGTGTTACGTTGATTGGTGGCGGGGCGCGTAGTGAG
TACTGGCGTCAAATGCTGGCGGACATCAGCGGTCAGCAACTGGATTACCGCACGGGTGGCGATGTGGGGCCAGCACTGGG
CGCAGCAAGGCTGGCGCAGATTGCGGCGAATCCAGAGAAATCGCTCATTGAGTTGTTGCCGCAACTACCGTTAGAACAGT
CGCATCTACCAGATGCGCAGCGTTATGCCGCTTATCAGCCACGACGAGAAACGTTCCGTCGCCTCTATCAGCAACTTCTG
CCATTAATGGCGTAA

Upstream 100 bases:

>100_bases
TGGTAAATCATTATCTGTTCGACAAATAACAGCTAACTGTGCAGTCCGTTGGCCCGGTTATCAGTAGCGATACCGGGCAT
TTTTTTAAGGAACGATCGAT

Downstream 100 bases:

>100_bases
ACGTTATCCCCTGCCTGACCGGGTGGGGGATAATTCACATCTATATATCTCAGTAATTAATTAATATTTAGTATGAATTT
ATTCTGAAAATCATTTGTTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMAAVPVIAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALITAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Sequences:

>Translated_484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMAAVPVIAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALITAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA
>Mature_484_residues
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMAAVPVIAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALITAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=437, Percent_Identity=22.4256292906178, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4504007, Length=436, Percent_Identity=22.4770642201835, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI189409120, Length=436, Percent_Identity=22.4770642201835, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI41393575, Length=437, Percent_Identity=23.1121281464531, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI164663828, Length=534, Percent_Identity=23.2209737827715, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI164663830, Length=557, Percent_Identity=22.0825852782765, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI18860918, Length=335, Percent_Identity=25.9701492537313, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=98.7603305785124, Blast_Score=978, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=492, Percent_Identity=23.780487804878, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790361, Length=492, Percent_Identity=23.5772357723577, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787789, Length=515, Percent_Identity=24.6601941747573, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789168, Length=421, Percent_Identity=26.1282660332542, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17535599, Length=442, Percent_Identity=23.7556561085973, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24655555, Length=459, Percent_Identity=23.7472766884532, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24655560, Length=459, Percent_Identity=23.7472766884532, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24655570, Length=459, Percent_Identity=23.7472766884532, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24655574, Length=459, Percent_Identity=23.7472766884532, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24655565, Length=459, Percent_Identity=23.7472766884532, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356607, Length=318, Percent_Identity=23.8993710691824, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52653; Mature: 52653

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMAAVPVIAGGGDNAAGAVG
HCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGLSNVPALITAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNE
HHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC
>Mature Secondary Structure
MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
VQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCAQECTLLEARVPQSRVITG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHCCCCCEEEEC
NLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRMTGEFASDMSDAAGTMWLDVA
CEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHCCCEEEHHH
KRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAKAWGMAAVPVIAGGGDNAAGAVG
HCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDW
EEEECCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGLSNVPALITAAQQADESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNE
HHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSEYWRQMLADISGQQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEECCCCC
DVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
PLMA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]