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The map label for this gene is gatY [H]

Identifier: 218691545

GI number: 218691545

Start: 3845115

End: 3845969

Strand: Reverse

Name: gatY [H]

Synonym: ECED1_3913

Alternate gene names: 218691545

Gene position: 3845969-3845115 (Counterclockwise)

Preceding gene: 218691555

Following gene: 218691544

Centisome position: 73.83

GC content: 48.19

Gene sequence:

>855_bases
ATGTATATTATTTCAAGCAAAAACATGCTGAAAAAAGCCCAGTCAGAGGGATATGCCGTCCCTGCTTTCAACATTCATAA
CCTTGAAACTTTACAGGTAGTTGTTGAGAGCGCTGCACAACTTCGCTCTCCCGTTATGCTGGCGGGAACACCCGGTACAT
ATCGTTATGGTGGCGTGGGAAGTTTAATTTCGTTAGTACAATCGCTGGCTCGCGAGTACAACCTGCCGTTAGTCCTGCAT
CTCGACCATCATGAAGAGAGTGATGACATTTTTAACAAGGTTCGCGCAGGGATCCGTTCTGTCATGATTGATGGCTCCCA
TTTGCCATTTGAAGACAACATTGCGCGAGTGCAAGAAGTTACCACCTTTTGCCATCGCTTTGATGTTAGCGTTGAGGCCG
AGCTAGGGCGTCTTGGCGGCCAGGAGGACGATCTGCGGGTGGATGAAAAAGATTCCGCTTATACCTCACCAGCCGCAGCT
GCAGAGTTTGTTCAACGTACCCAAATTGACTCCCTGGCGGTAGCAATCGGCACAGCACATGGTTTATATGCGCATGAACC
ACGACTGGATTTTGTGCGGCTGGAACAGATTCGTCAGCGAGTGGAGATTCCGCTGGTGTTGCATGGTGCTTCGGGCTTAT
CGGAACAGGACGTTCAGCACTGTATTCGTCGCGGTATTTGTAAAGTGAATGTCGCGACAGAATTGAAAATTGCGTTTGCC
GATGCGTTAAAAGGATATTTCTACAACAATCCTGCGGCAAATGATCCACGTCACTATATGCAGCCCGCAAAGGCCGCCAT
GAAAGAAGTCGTAACTCGTATTATTGGCGTCTGTGGTAGTGAAGGAAAAATTTAA

Upstream 100 bases:

>100_bases
CGCTTTTTGCTGCTTTTGCTGTGCTAGTTTGCTTTCAAAATGAAAGTAAAGATTCTCTTTCTTCATTTTGTAAGGCGAAC
GACAAATAACAGGAGCTGCG

Downstream 100 bases:

>100_bases
GACGTTGTACCCTACAAAAATAATGAGGATTGTTTATGAAAAATATTAAATTACTTGGTTCAGCTATGTTGGTGAGCCTG
GCATTGTTCTCGCAAAGTTC

Product: tagatose-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH
LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAA
AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA
DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI

Sequences:

>Translated_284_residues
MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH
LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAA
AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA
DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI
>Mature_284_residues
MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH
LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAA
AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA
DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=283, Percent_Identity=64.3109540636042, Blast_Score=396, Evalue=1e-112,
Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=56.6901408450704, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1788072, Length=275, Percent_Identity=37.4545454545455, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789293, Length=308, Percent_Identity=23.7012987012987, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322790, Length=329, Percent_Identity=25.531914893617, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 31312; Mature: 31312

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVG
CEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
SLISLVQSLAREYNLPLVLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
TTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAAAEFVQRTQIDSLAVAIGTAH
HHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEECHHHHHHHHH
DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVG
CEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
SLISLVQSLAREYNLPLVLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
TTFCHRFDVSVEAELGRLGGQEDDLRVDEKDSAYTSPAAAAEFVQRTQIDSLAVAIGTAH
HHHHHHHCCCEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCEEEECHHHHHHHHH
DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA