Click here to switch to the map view.

The map label for this gene is degQ [H]

Identifier: 218691516

GI number: 218691516

Start: 3813277

End: 3814644

Strand: Direct

Name: degQ [H]

Synonym: ECED1_3884

Alternate gene names: 218691516

Gene position: 3813277-3814644 (Clockwise)

Preceding gene: 218691515

Following gene: 218691517

Centisome position: 73.2

GC content: 52.19

Gene sequence:

>1368_bases
ATGAAAAAACAAACCCAGCTGTTGAGTGCATTAGCGTTAAGTGTCGGGTTAACTCTCTCGGCGTCATTTCAGGCCGTCGC
GTCGATTCCAGGCCAGGTTGCCGATCAGGCCCCCCTCCCCAGTCTGGCTCCAATGCTGGAAAAAGTGCTTCCGGCAGTGG
TGAGCGTACGGGTGGAAGGAACGGCCAGTCAGGGACAGAAAATCCCGGAAGAATTCAAAAAGTTTTTTGGTGATGATTTA
CCGGATCAACCTGCACAACCCTTCGAAGGTTTAGGCTCCGGTGTCATCATCAACGCCAATAAAGGCTATGTGCTGACCAA
CAACCATGTGATTAATCAGGCACAGAAAATCAGTATTCAGCTCAATGATGGGCGCGAGTTTGATGCAAAACTAATTGGTA
GCGATGACCAGAGCGATATCGCCCTGTTGCAAATTCAAAACCCGAGCAAATTAACGCAAATCGCTATTGCCGACTCCGAT
AAATTGCGCGTCGGTGATTTTGCCGTGGCGGTCGGTAACCCATTTGGCCTTGGGCAAACCGCCACCTCTGGCATTATATC
CGCATTAGGCCGCAGCGGGTTGAATCTTGAAGGTCTGGAAAACTTTATCCAGACAGATGCTTCCATTAACCGCGGTAACT
CCGGCGGTGCACTGTTAAACCTTAACGGTGAGTTAATTGGCATCAACACTGCAATCCTTGCGCCTGGCGGCGGTAGCGTC
GGGATTGGATTTGCCATTCCCAGTAATATGGCGCGAACACTGGCGCAGCAGCTTATCGACTTTGGAGAAATCAAACGCGG
CCTGTTAGGCATCAAAGGCACCGAGATGAGTGCCGATATCGCCAAGGCCTTCAACCTTGACGTGCAGCGTGGCGCGTTTG
TCAGCGAAGTGTTGCCAGGTTCTGGCTCGGCGAAAGCGGGCGTCAAAGCGGGCGATATTATTACCAGCCTCAACGGCAAA
CCGCTGAATAGCTTTGCTGAGTTGCGCTCTCGTATCGCGACCACCGAGCCGGGCACGAAAGTGAAGCTTGGCCTGCTGCG
TAACGGCAAACCACTGGAAGTAGAAGTGACGCTCGATACCAGCACCTCTTCGTCGGCCAGCGCTGAAATGATCACGCCAG
CGCTGGAAGGTGCAACGTTGAGCGATGGTCAGCTAAAAGATGGTGGCAAAGGTATTAAGATCGATGAGGTTGTCAAAGGA
AGCCCAGCTGCTCAGGCTGGCTTGCAAAAAGACGATGTGATCATTGGCGTCAACCGCGATCGGGTGAACTCGATTGCTGA
AATGCGTAAAGTGCTGGCGGCAAAACCGGCCATAATCGCCTTGCAAATCATACGCGGCAATGAAAGCCTCTACCTACTAA
TGCGTTAA

Upstream 100 bases:

>100_bases
TCATTTAATCTGGTGTCTCATTGTTAGCCGTCTGAAAATTCAATAACATCAAACTGTTTTGAATCTCTTTTCTTATCATT
CAGGTACGAGAGCAGGAATA

Downstream 100 bases:

>100_bases
TGTCGTAAACCGGGCATCAGGCTGACGTGTGATGTCCGGTTAACTCGTGGTATGCTGCTGCCGTTCCCTTTTTTAACGAT
GCCTCCATCATGTTTGTGAA

Product: serine endoprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIIRGNESLYLLMR

Sequences:

>Translated_455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIIRGNESLYLLMR
>Mature_455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIIRGNESLYLLMR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=36.0759493670886, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4506141, Length=294, Percent_Identity=35.3741496598639, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI24308541, Length=305, Percent_Identity=30.4918032786885, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=33.445945945946, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=99.1208791208791, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=440, Percent_Identity=57.5, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=45.0184501845018, Blast_Score=210, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=33.2179930795848, Blast_Score=129, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 47261; Mature: 47261

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEEEEC
TASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQ
CHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHH
ATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPG
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCCEEEECCHH
RVNSIAEMRKVLAAKPAIIALQIIRGNESLYLLMR
HHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEEEEC
TASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINANKGYVLTNNHVINQAQKISIQ
CHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCHH
ATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPG
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCCEEEECCHH
RVNSIAEMRKVLAAKPAIIALQIIRGNESLYLLMR
HHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]