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The map label for this gene is tdcD [H]

Identifier: 218691414

GI number: 218691414

Start: 3710263

End: 3711483

Strand: Reverse

Name: tdcD [H]

Synonym: ECED1_3780

Alternate gene names: 218691414

Gene position: 3711483-3710263 (Counterclockwise)

Preceding gene: 218691415

Following gene: 218691413

Centisome position: 71.24

GC content: 47.99

Gene sequence:

>1221_bases
ATGAGAAAAGAGATGAATGAATTTCCGGTTGTTTTGGTTATTAACTGTGGTTCGTCTTCGATTAAGTTTTCCGTACTCAA
TGCCAGCGACTGTGAAGTATTAATGTCAGGTATTGCCGACGGTATTAACTCGAAAAATGCATTCTTATCCGTAAATGGGG
GAGAGCCAGCACCGCTGGCTCACCACAGCTACGAAGGTGCATTGAAGGCAATTGCATTTGAACTGGAAAAACGGAATTTA
AATGACAGTGTGGTCTTAATTGGCCACCGCATCGCTCACGGCGGCAGTATTTTTACCGAGTCCGCCATTATTACCGATGA
AGTCATTGATAATATCCGTCGCGTTTCTCCACTGGCACCCCTGCATAATTACGCCAATTTAAGTGGTATTGAATCGGCGC
AGCAATTATTCCCGGGCGTAACTCAGGTGGCGGTATTTGATACCAGTTTCCACCAGACGATGGCTCCGGAAGCTTATTTA
TACGGCCTGCCGTGGAAATATTATGAAGAGTTAGGTGTACGCCGTTATGGTTTCCACGGCACGTCGCACCGCTATGTTTC
CCAGCGCGCGCATTCTCTGCTGAATCTGGCGGAAGATGACTCCGGCCTGGTTGTGGCGCATCTTGGCAATGGCGCGTCAA
TCTGCGCGGTTCGCAACGGTCAGAGTGTTGACACTTCCATGGGAATGACGCCGCTGGAAGGCTTGATGATGGGTACCCGC
AGTGGTGATGTCGACTTCGGGGCGATGTCCTGGGTCGCCAGCCAAACCAACCAGAGCCTGGGGGACCTGGAACGCGTAGT
GAATAAAGAGTCGGGATTATTAGGTATTTCCGGCCTTTCTTCGGATTTACGTGTTCTGGAAAAAGCCTGGCATGAAGGTC
ACGAACGCGCGCAACTGGCAATTAAAACCTTTGTTCACCGAATTGCCCGTCATATTGCCGGACACGCTGCTTCATTACAT
CGCCTGGATGGAATTATATTCACCGGCGGAATAGGAGAGAATTCAAGTTTAATTCGTCGTCTGGTCATGGAACATTTAGC
TGTATTAGGCGTAGAAATTGATACAGAAATGAATAATCGCTCTAACTCTTTTGGAGAGCGAATTGTTTCCAGTGAAAATG
CGCGTGTCATTTGCGCCGTAATTCCGACTAACGAAGAAAAAATGATTGCTTTGGATGCCATTCATTTAGGCAAAGTGAAC
GCGCCCGCAGAATTTGCATAA

Upstream 100 bases:

>100_bases
GCGAAATACCGTGGTCGTCTGGATAACGTGTTTGTTACCGTGATTGGTCTGCTGACCATCCTGAACATCGTATACAAACT
GTTTTAATCCGTAACTCAGG

Downstream 100 bases:

>100_bases
TTTAGTTGAAGTATTGTAGAGAGATTATTTTTCATGAAGGTAGATATTGATACCAGCGATAAGCTGTACGCCGACGCATG
GCTTGGCTTTAAAGGTACGG

Product: propionate/acetate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRKEMNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSKNAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNL
NDSVVLIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYL
YGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTR
SGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLH
RLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVN
APAEFA

Sequences:

>Translated_406_residues
MRKEMNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSKNAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNL
NDSVVLIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYL
YGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTR
SGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLH
RLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVN
APAEFA
>Mature_406_residues
MRKEMNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSKNAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNL
NDSVVLIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYL
YGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTR
SGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLH
RLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVN
APAEFA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family. TdcD subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=98.5074626865672, Blast_Score=809, Evalue=0.0,
Organism=Escherichia coli, GI1788633, Length=397, Percent_Identity=44.080604534005, Blast_Score=314, Evalue=8e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.15 [H]

Molecular weight: Translated: 43966; Mature: 43966

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKEMNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSKNAFLSVNGGEPAPLA
CCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HHSYEGALKAIAFELEKRNLNDSVVLIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAP
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHCCCCH
LHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHG
HHHHCCCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCEEECCCHHHHHHCCCEEECCCC
TSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTR
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCC
SGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLA
CCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHH
IKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNR
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCC
SNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
CCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRKEMNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSKNAFLSVNGGEPAPLA
CCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
HHSYEGALKAIAFELEKRNLNDSVVLIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAP
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHCCCCH
LHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHG
HHHHCCCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCEEECCCHHHHHHCCCEEECCCC
TSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTR
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCC
SGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLA
CCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHH
IKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNR
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCC
SNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
CCHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA