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The map label for this gene is aer [H]

Identifier: 218691376

GI number: 218691376

Start: 3666589

End: 3668109

Strand: Reverse

Name: aer [H]

Synonym: ECED1_3740

Alternate gene names: 218691376

Gene position: 3668109-3666589 (Counterclockwise)

Preceding gene: 218691378

Following gene: 218691374

Centisome position: 70.41

GC content: 54.7

Gene sequence:

>1521_bases
ATGTCTTCTCATCCGTATGTCACCCAGCAAAATACCCCGCTGGCGGACGACACCACTCTGATGTCCACTACCGATCTGCA
AAGCTATATCACTCATGCTAATGACACTTTTGTGCAGGTGAGCGGCTATACCTTGCAAGAGTTACAGGGGCAGCCGCACA
ACATGGTGCGTCACCCGGATATGCCAAAAGCGGCGTTTGCGGATATGTGGTTCACCCTGAAAAAAGGGGAGCCCTGGAGC
GGCATCGTGAAAAATCGCCGCAAAAATGGCGACCATTATTGGGTGCGGGCCAATGCGGTACCGATGGTGCGCGAGGGAAA
AATCAGTGGCTATATGTCGATTCGTACCCGGGCGACGGATGAAGAGATCGCGGCGGTGGAGCCGCTGTACAAAGCGTTGA
ACGCCGGACGTACCAGTAAGCGTATTCATAAAGGCCTGGTGGTGCGTAAAGGCTGGCTGGGTAAACTGCCTTCATTACCG
CTTCGCTGGCGGGTGCGTGGAGTGATGACCCTGATGTTTATCGTGCTGGCGGCCATGCTCTGGTTTGTCGCTGCCCCGGT
GGTGACGTATTTCCTCTGTGCGTTAGTGATGTTGTTGGGAAATGCCTGTTTTGAATGGCAAATTGTACGTCCGATAGAAA
ATGTCGCCAGCCAGGCACTGAAAGTGGCGATCGGAGAACGTAATAGTGTTGAGCATCTGAAGCGCAGCGATGAGCTGGGG
CTGACATTACGTGCGGTAGGGCAGCTTGGCCTGATGTGCCGTTGGCTAATTAATGATGTCTCAAGCCAGGTGTCCAGTGT
CAGAAACGGCAGTGAGACGCTGGCGAAAGGCACCGATGAACTGAACGAACATACCCAGCAGACAGTTGATAACGTTCAGC
AAACGGTGGCGACCATGAACCAAATGGCGGCGTCGGTGAAACAGAACTCTGCCACGGCGTCGGCTGCCGATAAACTTTCT
ATCACCGCCAGTAATGCGGCAGTGCAGGGCGGGGAGGCGATGACTACGGTGATCAAGACAATGGACGATATTGCCGACAG
TACCCAGCGCATTGGCACCATTACTTCGCTGATTAACGATATTGCGTTTCAGACCAATATTCTGGCCCTGAATGCGGCGG
TGGAAGCGGCGCGTGCCGGCGAACAGGGCAAAGGTTTTGCAGTGGTGGCGGGGGAAGTGCGTCATTTAGCCAGCCGCAGC
GCCAATGCTGCCAACGATATTCGCAAGCTGATTGATGCCAGTGCTGATAAGGTGCAATCTGGTTCGCAGCAGGTACACGC
CGCCGGACGGACGATGGAAGATATTGTGGCGCAGGTAAAAAACGTCACCCAGTTGATAGCTCAGATTAGCCATTCAACGC
TGGAACAGGCCGATGGGCTTTCCAGCCTGACCCGTGCAGTGGATGAGCTTAACCTGATCACCCAGAAAAACGCCGAGTTA
GTGGAAGAGAGTGCGCAGGTGTCGGCGATGGTGAAACACCGCGCCAACCGACTGGAAGACGCGGTGACGGTGCTGCATTA
A

Upstream 100 bases:

>100_bases
GCGATCTAAATCAAATTAATTGGTTAAAGATAACCGCAGCGGGGCCGACATAAACTCTGACAAGAAGTTAACAACCATAT
AACCTGCACAGGACGCGAAC

Downstream 100 bases:

>100_bases
TCGGTATGCCGGATCCGGCGGTTGGAGCACAATGCCTGATGCGATGCTGGCGCATCTTATCAGGCCTACGGGGTGTGTAG
GGTACGCTGCATCCGGCAAT

Product: fused signal transducer for aerotaxis sensory component ; methyl accepting chemotaxis component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWS
GIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
LRWRVRGVMTLMFIVLAAMLWFVAAPVVTYFLCALVMLLGNACFEWQIVRPIENVASQALKVAIGERNSVEHLKRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLS
ITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRANRLEDAVTVLH

Sequences:

>Translated_506_residues
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWS
GIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
LRWRVRGVMTLMFIVLAAMLWFVAAPVVTYFLCALVMLLGNACFEWQIVRPIENVASQALKVAIGERNSVEHLKRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLS
ITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRANRLEDAVTVLH
>Mature_505_residues
SSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSG
IVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPL
RWRVRGVMTLMFIVLAAMLWFVAAPVVTYFLCALVMLLGNACFEWQIVRPIENVASQALKVAIGERNSVEHLKRSDELGL
TLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSI
TASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSA
NAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAELV
EESAQVSAMVKHRANRLEDAVTVLH

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=506, Percent_Identity=98.0237154150198, Blast_Score=1022, Evalue=0.0,
Organism=Escherichia coli, GI1787690, Length=327, Percent_Identity=40.6727828746177, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1788195, Length=268, Percent_Identity=45.5223880597015, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367378, Length=349, Percent_Identity=40.4011461318052, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1788194, Length=249, Percent_Identity=46.1847389558233, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 55163; Mature: 55031

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCCC
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
CCHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEEEECCCC
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRVRGVMTLMFIVLAAML
HHHHHHHHHHHHHHCCCHHHHHHHCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFVAAPVVTYFLCALVMLLGNACFEWQIVRPIENVASQALKVAIGERNSVEHLKRSDELG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
HHHHHHHHCCCHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHC
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHH
VEESAQVSAMVKHRANRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCCC
MPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATD
CCHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEEEECCCC
EEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRVRGVMTLMFIVLAAML
HHHHHHHHHHHHHHCCCHHHHHHHCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WFVAAPVVTYFLCALVMLLGNACFEWQIVRPIENVASQALKVAIGERNSVEHLKRSDELG
HHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHCC
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLIND
HHHHHHHHCCCHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHC
GSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHH
VEESAQVSAMVKHRANRLEDAVTVLH
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]