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The map label for this gene is mdaB [H]

Identifier: 218691326

GI number: 218691326

Start: 3612297

End: 3612878

Strand: Direct

Name: mdaB [H]

Synonym: ECED1_3687

Alternate gene names: 218691326

Gene position: 3612297-3612878 (Clockwise)

Preceding gene: 218691323

Following gene: 218691327

Centisome position: 69.34

GC content: 50.0

Gene sequence:

>582_bases
ATGAGCAACATCCTGATTATCAACGGCGCGAAAAAATTCGCCCACTCCAATGGTCAACTGAACGACACCCTGACCGAAGT
CGCGGATGGCACACTGCGCGACCTCGGGCATGATGTCCGCATCGTTCGCGCCGACAGCGACTACGATGTCAAAGCGGAAG
TACAAAACTTTCTCTGGGCTGATGTGGTGATCTGGCAGATGCCTAGCTGGTGGATGGGCGCGCCGTGGACAGTGAAAAAA
TATATTGATGATGTATTCACCGAAGGTCACGGGACTCTGTATGCCAGCGATGGTCGTACCCGCAAAGATCCATCAAAAAA
ATACGGTTCCGGCGGCCTGGTACAGGGCAAAAAATATATGCTTTCTCTGACCTGGAACGCACCAATGGAAGCCTTCACCG
AAAAAGATCAGTTCTTCTACGGCGTTGGGGTTGACGGTGTGTACCTGCCGTTCCATAAAGCAAACCAGTTCCTTGGCATG
GAACCGCTGCCGACATTTATCGCTAATGACGTGATAAAAATGCCTGATGTTCCCCGCTATACTGAAGAATATCGCAAGCA
TCTTGTGGAAATTTTTGGTTAA

Upstream 100 bases:

>100_bases
TTTTGCTAAATTCGCAAAAGACTTTGCACATTTTGCTAATTTCACCGTACCGCTCTGTGACGTACTATAGTCGGCAAACG
TCTCACCTTGAGGTTAAAAA

Downstream 100 bases:

>100_bases
CTAGAGCTCTGGCTTTAGAAGGAGTTAACCATGATTACAGTAATCGCAGAAATCCGTACTCGTCCTGGTCAACATCACCG
TCAGGCAGTGTTGGATCAGT

Product: NADPH quinone reductase

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWADVVIWQMPSWWMGAPWTVKK
YIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFYGVGVDGVYLPFHKANQFLGM
EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG

Sequences:

>Translated_193_residues
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWADVVIWQMPSWWMGAPWTVKK
YIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFYGVGVDGVYLPFHKANQFLGM
EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG
>Mature_192_residues
SNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWADVVIWQMPSWWMGAPWTVKKY
IDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFYGVGVDGVYLPFHKANQFLGME
PLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=193, Percent_Identity=98.9637305699482, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21947; Mature: 21816

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWA
CCCEEEEECCHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
DVVIWQMPSWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYM
HHHEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCEEECCEEE
LSLTWNAPMEAFTEKDQFFYGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRY
EEEEECCCHHHHCCCCCEEEEECCCCEEECHHHCCCCCCCCCCHHHHHCCCCCCCCCCCH
TEEYRKHLVEIFG
HHHHHHHHHHHCC
>Mature Secondary Structure 
SNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWA
CCEEEEECCHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
DVVIWQMPSWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYM
HHHEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCEEECCEEE
LSLTWNAPMEAFTEKDQFFYGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRY
EEEEECCCHHHHCCCCCEEEEECCCCEEECHHHCCCCCCCCCCHHHHHCCCCCCCCCCCH
TEEYRKHLVEIFG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]