Click here to switch to the map view.

The map label for this gene is uxuR [H]

Identifier: 218691308

GI number: 218691308

Start: 3593282

End: 3594031

Strand: Direct

Name: uxuR [H]

Synonym: ECED1_3668

Alternate gene names: 218691308

Gene position: 3593282-3594031 (Clockwise)

Preceding gene: 218691306

Following gene: 218691309

Centisome position: 68.97

GC content: 44.8

Gene sequence:

>750_bases
ATGGAACAGGTTATTACAAAGCGCCGCTATTACGATATTGGTCTACAGATTGAAGAGCTGCTGTATTCAGGCGTATTCAA
AGCCGGAGAACGCTTACCTTCAGAACGTGAACTGAGCGAGCGGTTTAATACCAGCCGAACTACCATTCGTGAAGCCATTA
TTATGCTGGAACTGAAAGGCGTATTGAATGTGAAGCAAGGGTCAGGGATTTTCTTTGTCGACTCCACCGATAAGCTCAAC
CAGAAATCATTAATGCCCTATTCAGAAATTGGCCCGTTTGAACTGTTGCAGGCGCGTCAGGTGATTGAGAGCAATATTAC
TGGTTTTGCAGCCAGCCAGATTAGCTTTAACGAGTTACAAGAGTTAAAGAAAATCATTGGATTACAGGAAAAAGCCATCG
CTGCGGAAAGTGATAAATTTGAAGACCTGGATCACCGATTTCATAGCATTATTGCCGAAGCGACGCAAAATCGGGTACTC
ATCAAACAAGCCGCTGAATTATGGCGGGCAGTGCGCACAGAAAACCCCCGCTGGAAGAAACTTAACTACAAGTACCTGCA
TGAAAAGCATTTGCGTCTGCAATGGCTGGAAGATCACCGGGCTATTTTCCTGGCTCTGCAACAGAAAGATTCAGAGCTCG
CCAGGGAAGCGTCCTGGAGACATCTGGAAAACAGCAAAAATGAACTGATCAAAATCTTCAAACAAGACGCTTCCATCAGC
GATTTTGATGACTTTTTCTTCGCTCGTTAA

Upstream 100 bases:

>100_bases
GTATCGTGGCAACTGCCGCTACTATTTATGCCGATCAGCAACGTTCAAATCATATTGCACGACGATCGGCTATCCGAGGA
CACCCACAGTAAGGCAAGGT

Downstream 100 bases:

>100_bases
CCTTCATTAGTCCAGAGCTGACGTGAAAAATGACGCTGGCTCTGCGTTGCACCCTCCACTGGTATACGCTCCCTTCTCAA
TTGGTCTAATAAATCGATTA

Product: putative regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQGSGIFFVDSTDKLN
QKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVL
IKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKNELIKIFKQDASIS
DFDDFFFAR

Sequences:

>Translated_249_residues
MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQGSGIFFVDSTDKLN
QKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVL
IKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKNELIKIFKQDASIS
DFDDFFFAR
>Mature_249_residues
MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQGSGIFFVDSTDKLN
QKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVL
IKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKNELIKIFKQDASIS
DFDDFFFAR

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=247, Percent_Identity=38.4615384615385, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=38.0952380952381, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1786303, Length=220, Percent_Identity=33.1818181818182, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790032, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=27.4336283185841, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29181; Mature: 29181

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKG
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
VLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQ
HEEEECCCCEEEECCCCCCCHHHCCCHHHCCHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
ELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVLIKQAAELWRAVRTENPRWKK
HHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEE
LNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKNELIKIFKQDASIS
CCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
DFDDFFFAR
CHHHHHHCC
>Mature Secondary Structure
MEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKG
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
VLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQ
HEEEECCCCEEEECCCCCCCHHHCCCHHHCCHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
ELKKIIGLQEKAIAAESDKFEDLDHRFHSIIAEATQNRVLIKQAAELWRAVRTENPRWKK
HHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEE
LNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKNELIKIFKQDASIS
CCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
DFDDFFFAR
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]