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The map label for this gene is yesM [H]

Identifier: 218691125

GI number: 218691125

Start: 3407158

End: 3408420

Strand: Direct

Name: yesM [H]

Synonym: ECED1_3468

Alternate gene names: 218691125

Gene position: 3407158-3408420 (Clockwise)

Preceding gene: 218691124

Following gene: 218691126

Centisome position: 65.4

GC content: 42.99

Gene sequence:

>1263_bases
ATGATTATGTTTTTAAAAATGCAGGCTGAAAGTATGAAGAATAAATACAAATTAAATGAGTTTTTGGATGTAAAACGCCT
TCAGACCCTGCAGGACAACTTTTCAAAATCAATGATGATCGCGCTCGTGGTTGTGGATGAGAATGGTATCCCGGTCACTA
AGCCCAGCGGTTTTTCAGACTTCTGCATGCGTTCGCGTCTCAACCCGACACTGGCGCACCACTGTTATGAAAGCGACAAC
GCTGGTGGCCGTGCCGCGATGCACGCTCGCAAACCGGTGGTTTATCGCTGCCACTGCGGTTTTGTCGAATTCGCTGTCCC
AATCATGATTAACGATCATTATCTCGGTGCTTTTATTTCCGGTCAGGTAAAAGTCGAAGAAGAGAAAGAACAGAGCATTT
CCTATATTCTGAATAATAATGACGTCTGGAAAGATAATCCTTGGTTAATTAATTTGCACCAGAATACACGTCGCATGCCG
TATGAGCGTTTTGAGTCTACTGCCTCGACGTTACTACACGTATCGTCTTATCTGGTCGAACAAGCGCACACCAATAATAT
CCAACGCGAACTTCGTAAAAAGGATCTTGCACTGGCTAATGAGTTAAGAAAACGTGTAGAGATAGAACGCTCACTACATG
AAGCTGAATTTAAAGCGCTCTCTTATCAGATAAATCCACACTTTTTATTTAACGTATTAAATACCATTGGCCGGTTAGCT
TTTCTTGAAGATGCGCAGCGTACCGAAACAATGGTGCACGATTTCTCTGACATGATGCGCTATTTGTTACGTAAAAATAG
TCACGGCCTGATTACTCTGCGTAATGAAATAAATTACGTCAACAACTATATGTCGATCCAAAAAGTGCGTATGAGAGACC
GTTTCGATTACCTGTGCGATATCCCGGAAAAATATCTGGATGTAGTCTGCCCGTTTTTGATCCTGCAACCGCTGGTGGAA
AACTTCTTTAACTACGTAGTGGAGCCAAGGGATAGCAATAGTCATCTGCTGATCCGTGCCACGGACGATGGCCTGAACGT
GATTATTGAAGTCACTGACAATGGCGACGGCATCGCACCAGATACCATTAATCGCATTTTATCAGGCGACCAAAAATTGC
AAAAAGGCAGTATTGGCATTAACAACATAAAAAATAGATTGAAGTTGTTATTTGGCGAGAGCTATGGCTTGGAAATAATG
AGCCCTAACAAACCCAGGATGGGTACAACCATTAAACTTCGGTTCCCAATGCAGGAAGCCTGA

Upstream 100 bases:

>100_bases
GTATCCCTTGCAAATAACCGAAGCATTACTTTCAGAGCCGGAGCTGTTTTTGTTGCTGTGATCCATTTCAATTTTTTCGC
GACAAATTATTTATAAATAT

Downstream 100 bases:

>100_bases
TACAGGAAAAGGACATATGTTTACCATTGTTATCGTTGAAGATGAGCCCATCGAATTAGAATCCCTGCGGCAGATTATCT
CCCAGTGTGTGGAAAACGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MIMFLKMQAESMKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKPSGFSDFCMRSRLNPTLAHHCYESDN
AGGRAAMHARKPVVYRCHCGFVEFAVPIMINDHYLGAFISGQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMP
YERFESTASTLLHVSSYLVEQAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLA
FLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVE
NFFNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIM
SPNKPRMGTTIKLRFPMQEA

Sequences:

>Translated_420_residues
MIMFLKMQAESMKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKPSGFSDFCMRSRLNPTLAHHCYESDN
AGGRAAMHARKPVVYRCHCGFVEFAVPIMINDHYLGAFISGQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMP
YERFESTASTLLHVSSYLVEQAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLA
FLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVE
NFFNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIM
SPNKPRMGTTIKLRFPMQEA
>Mature_420_residues
MIMFLKMQAESMKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKPSGFSDFCMRSRLNPTLAHHCYESDN
AGGRAAMHARKPVVYRCHCGFVEFAVPIMINDHYLGAFISGQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMP
YERFESTASTLLHVSSYLVEQAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLA
FLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVE
NFFNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIM
SPNKPRMGTTIKLRFPMQEA

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=330, Percent_Identity=26.969696969697, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788446, Length=208, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48694; Mature: 48694

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMFLKMQAESMKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKPSGFSD
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCHH
FCMRSRLNPTLAHHCYESDNAGGRAAMHARKPVVYRCHCGFVEFAVPIMINDHYLGAFIS
HHHHHCCCHHHHHHCCCCCCCCCCEEHHCCCCEEEEEECCHHHEEEEEEEECCEEEEEEE
GQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMPYERFESTASTLLHVSSYLVE
CEEEECCHHHCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHH
FLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
IPEKYLDVVCPFLILQPLVENFFNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAP
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCH
DTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIMSPNKPRMGTTIKLRFPMQEA
HHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MIMFLKMQAESMKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKPSGFSD
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCHH
FCMRSRLNPTLAHHCYESDNAGGRAAMHARKPVVYRCHCGFVEFAVPIMINDHYLGAFIS
HHHHHCCCHHHHHHCCCCCCCCCCEEHHCCCCEEEEEECCHHHEEEEEEEECCEEEEEEE
GQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMPYERFESTASTLLHVSSYLVE
CEEEECCHHHCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHH
FLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
IPEKYLDVVCPFLILQPLVENFFNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAP
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCH
DTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIMSPNKPRMGTTIKLRFPMQEA
HHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]