Click here to switch to the map view.

The map label for this gene is ygfU [H]

Identifier: 218691013

GI number: 218691013

Start: 3296880

End: 3298328

Strand: Direct

Name: ygfU [H]

Synonym: ECED1_3347

Alternate gene names: 218691013

Gene position: 3296880-3298328 (Clockwise)

Preceding gene: 218691010

Following gene: 218691014

Centisome position: 63.29

GC content: 49.55

Gene sequence:

>1449_bases
ATGAGCGCCATAGATTCCCAACTTCCCTCATCTTCTGGGCAAGACCGCCCAACTGATGAGGTTGACCGCATATTATCACC
TGGAAAGCTGATCATACTCGGTCTGCAACACGTCCTTGTCATGTACGCAGGTGCAGTCGCTGTTCCTCTTATGATTGGTG
ACCGACTCGGCCTATCAAAAGAAGCTATTGCGATGCTCATCAGCTCGGATCTCTTTTGCTGCGGGATCGTCACATTATTG
CAATGTATCGGTATCGGCCGCTTTATGGGGATCCGCCTGCCGGTGATTATGTCGGTGACCTTCGCCGCTGTAACACCAAT
GATAGCTATTGGTATGAACCCGGATATCGGCCTGCTGGGGATATTCGGTGCCACTATCGCCGCGGGTTTTATCACCACAT
TATTAGCGCCACTTATCGGTCGCTTGATGCCTTTATTCCCGCCACTGGTTACCGGTGTGGTTATTACTTCTATCGGGCTT
AGCATCATTCAGGTGGGTATTGACTGGGCCGCCGGAGGTAAAGGGAATCCGCAATATGGTAATCCCGTTTATTTAGGTAT
CTCCTTTGCCGTCTTAATTTTTATCTTGCTCATTACTCGCTATGCGAAAGGATTTATGTCCAACGTCGCCGTATTACTGG
GGATTGTATTTGGCTTTTTACTTTCGTGGATGATGAATGAAGTCAATTTATCCGGGCTACATGATGCTTCATGGTTTGCG
ATTGTCACGCCGATGTCATTTGGTATGCCGATTTTCGATCCCGTTTCCATTCTGACCATGACTGCCGTGTTAATCATCGT
GTTTATCGAGTCGATGGGGATGTTCCTGGCACTGGGTGAAATAGTCGGTCGTAAACTCTCTTCACACGATATTATTCGCG
GGCTGCGTGTCGATGGTGTAGGGACAATGATAGGCGGAACGTTTAACAGCTTCCCCCACACGTCATTTTCTCAAAACGTT
GGCCTGGTTAGCGTGACGCGCGTTCATAGCCGCTGGGTGTGCATTGCTTCCGGTATCATTTTGATCCTGTTCGGCATGGT
GCCCAAAATGGCGGTGCTGGTGGCCTCCATTCCGCAATTTGTGCTGGGCGGCGCGGGGCTGGTGATGTTCGGCATGGTAC
TGGCGACAGGGATTCGAATTCTGTCGCGCTGTAACTACACCACTAACCGTTACAACCTCTATATTGTGGCGATCAGTCTC
GGTGTTGGCATGACGCCAACGCTCTCTCACGATTTCTTTTCTAAGTTACCGGCCGTACTGCAACCGTTGCTGCATAGCGG
CATTATGCTCGCAACCCTTAGCGCCGTTGTGCTGAACGTCTTCTTTAATGGCTACCAGCATCATGCTGACCTGGTGAAGG
AATCCGTCTCTGATAAAGATTTAAAAGTCAGGACAGTACGTATGTGGCTTCTGATGCGCAAGCTGAAGAAAAATGAGCAT
GGAGAATAA

Upstream 100 bases:

>100_bases
CCTTCCTCGCAAAAACTGGCACTCCACGAGCATGTGTTTAGACAGTTTCATGAACATAAACGGTTGCTTTTTACTCTGGC
GGGCGAAAGGAGAAACACTG

Downstream 100 bases:

>100_bases
TATGAATCTTTTAATGCGCGCTATATTCAGTCTGCTGTTGCTTTTTACTCTCTCTATTCCTGTCATTTCTGATTGTGTTG
CAATGGCCATTGAAAGTCGC

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLL
QCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFA
IVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNV
GLVSVTRVHSRWVCIASGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISL
GVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEH
GE

Sequences:

>Translated_482_residues
MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLL
QCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFA
IVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNV
GLVSVTRVHSRWVCIASGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISL
GVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEH
GE
>Mature_481_residues
SAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQ
CIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGLS
IIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAI
VTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVG
LVSVTRVHSRWVCIASGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLG
VGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHG
E

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=444, Percent_Identity=25, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI40316845, Length=444, Percent_Identity=25, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI44680145, Length=437, Percent_Identity=25.858123569794, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI44680143, Length=441, Percent_Identity=25.6235827664399, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI87082181, Length=482, Percent_Identity=99.7925311203319, Blast_Score=957, Evalue=0.0,
Organism=Escherichia coli, GI1790087, Length=460, Percent_Identity=28.695652173913, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87082178, Length=465, Percent_Identity=26.4516129032258, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788843, Length=391, Percent_Identity=27.6214833759591, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081818, Length=457, Percent_Identity=26.0393873085339, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17558856, Length=472, Percent_Identity=23.5169491525424, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17541904, Length=463, Percent_Identity=20.9503239740821, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=450, Percent_Identity=22.8888888888889, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993493, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356175, Length=458, Percent_Identity=23.7991266375546, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 51743; Mature: 51612

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSK
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLG
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
IFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGV
EECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEECCC
GTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCIASGIILILFGMVPKMAVLVASIPQF
HHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVL
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
QPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GE
CC
>Mature Secondary Structure 
SAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLGLSK
CCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLG
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
IFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
NPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
IVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIIRGLRVDGV
EECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEECCC
GTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCIASGIILILFGMVPKMAVLVASIPQF
HHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVL
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
QPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEH
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]