Click here to switch to the map view.

The map label for this gene is ygdL [H]

Identifier: 218690936

GI number: 218690936

Start: 3202477

End: 3203283

Strand: Reverse

Name: ygdL [H]

Synonym: ECED1_3266

Alternate gene names: 218690936

Gene position: 3203283-3202477 (Counterclockwise)

Preceding gene: 218690937

Following gene: 218690933

Centisome position: 61.49

GC content: 55.02

Gene sequence:

>807_bases
ATGTCTGTGGTAATTAGTGATGCATGGCGTCAGCGTTTTGGTGGCACAGCGCGTCTGTATGGTGAAAAAGCATTGCAACT
GTTTGCTGACGCGCATATTTGTGTGGTTGGTATCGGTGGTGTCGGTTCCTGGGCGGCGGAAGCGCTAGCGCGCACGGGGA
TTGGCGCAATCACGCTTATCGATATGGATGATGTGTGCGTCACCAATACCAATCGGCAAATTCACGCTCTGCGCGATAAC
GTCGGGCTGGCAAAAGCGGAAGTAATGGCGGAGCGTATTCGCCAGATTAACCCGGAGTGCCGTGTAACGGTGGTGGATGA
CTTCGTGACGCCGGATAACGTAGCGCAATATATGAATGCCGGTTATTCGTACGTGATTGATGCTATTGATAGTGTACGGC
CCAAAGCGGCGCTGATTGCTTATTGTCGGCGCAATAAAATCCCGCTGGTCACGACCGGTGGCGCTGGTGGGCAGATTGAC
CCGACGCAGATTCAGGTTACCGATCTGGCGAAAACGATTCAGGACCCGTTGGCGGCGAAGTTGCGCGAGCGCCTGAAAAG
CGATTTTGGCGTAGTGAAAAACAGTAAAGGTAAGCTCGGCGTGGATTGCGTGTTCTCTACCGAAGCGCTGGTGTACCCGC
AGTCAGACGGCACCGTCTGTGCGATGAAAGCCACGGCGGAAGGGCCAAAGCGGATGGATTGTGCCTCAGGATTTGGCGCG
GCGACGATGGTGACCGCCACTTTTGGCTTTGTTGCGGTTTCTCATGCGCTGAAGAAGATGATGGCGAAAGCGGCGCGTCA
GGGGTAA

Upstream 100 bases:

>100_bases
GCAGGTAACGTCTTTAGCGGCTGATGTGATATTCTGTATGCCGTTTTTACGGATATGACAGGGTGAGGGGTAACCTCACC
CTTTTTAATTCTGAGGTGCT

Downstream 100 bases:

>100_bases
ACAATCAGGTCGGATGCGACGCGAACGTCTTATCCGACCTGGTTCTGTGCTTAAACCTGCTTCGCCGCAGCGATAATCGC
CTCGCTTAACGCATTCAACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMNAGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMMAKAARQG

Sequences:

>Translated_268_residues
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDN
VGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMNAGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMMAKAARQG
>Mature_267_residues
SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNV
GLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMNAGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDP
TQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAA
TMVTATFGFVAVSHALKKMMAKAARQG

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=143, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1789177, Length=268, Percent_Identity=99.2537313432836, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI87082356, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=33.587786259542, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321790, Length=205, Percent_Identity=25.3658536585366, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=201, Percent_Identity=31.3432835820896, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582879, Length=132, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24660640, Length=137, Percent_Identity=29.9270072992701, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28561; Mature: 28430

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLI
CEEEECHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMNA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHC
GYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAK
CHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
LRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCEEEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKMMAKAARQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLI
EEEECHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMNA
ECCCEEEECCCCEEEEHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHC
GYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPTQIQVTDLAKTIQDPLAAK
CHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
LRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCEEEEEEEECCEEEEECCCCCEEEEEECCCCCCCCHHHCCCCH
ATMVTATFGFVAVSHALKKMMAKAARQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]