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The map label for this gene is xni [H]

Identifier: 218690921

GI number: 218690921

Start: 3188356

End: 3189201

Strand: Direct

Name: xni [H]

Synonym: ECED1_3251

Alternate gene names: 218690921

Gene position: 3188356-3189201 (Clockwise)

Preceding gene: 218690920

Following gene: 218690924

Centisome position: 61.2

GC content: 52.36

Gene sequence:

>846_bases
TTGCGAGGCCTCTTCCCGATTTCTCATCCAGCCATAGCCTGTTCTGGCATCGAATGTTACCCTTATCGCCTGATCTTTAA
GGGGGTTATCGTGGCTGTTCATTTGCTTATTGTCGATGCACTGAATCTTATTCGTCGCATTCATGCCGTTCAGGGTTCGC
CCTGTGTCGAAACCTGCCAGCACGCGCTCGATCAGCTCATTATGCACAGCCAGCCAACCCACGCGGTCGCCGTTTTTGAT
GATGAAAACCGCAGTAGCGGCTGGCGTCATCAGCGTTTACCAGATTACAAAGCGGGTCGACCGCCAATGCCGGAAGAGTT
GCACAACGAGATGCCTGCATTACGCGCCGCCTTTGAGCAACGTGGCGTCCCGTGCTGGTCCGCCAGCGGCAACGAAGCCG
ATGACTTAGCCGCCACGCTGGCGGTCAAAGTGACACAGGCCGGGCATCAGGCAACGATTGTTTCGACAGATAAAGGCTAC
TGTCAGTTACTTTCACCGACATTACGTATTCGTGATTACTTCCAGAAACGTTGGCTGGATGCGCCATTTATCGATAAAGA
ATTTGGCGTTCAACCGCAGCAGTTGCCCGATTACTGGGGGCTTGCGGGGATCAGCAGTTCAAAGGTACCGGGTGTTGCGG
GGATCGGACCAAAAAGCGCCACACAGCTACTGGTCGAGTTTCAGAGTCTGGAAGGGATATATGAGAATCTGGATGCGGTT
GCCGAAAAGTGGCGCAAAAAATTAGAAACCCATAAAGAGATGGCGTTTCTGTGCCGCGATATTGCCCGCTTACAAACCGA
TATGCATATCGACGGCAATTTACAGCAATTGCGGTTGGTAAGGTAA

Upstream 100 bases:

>100_bases
AACAGGTAAAGATATGAACGCCAAGTACCGCGAAACCTCTCGCGGCGGCCTGGCAATGAAGATCGTTGCCTGCGATTAAT
CGCTCTCCAGAGGCCTCTTT

Downstream 100 bases:

>100_bases
CGGCGTGCCGGATGCAAACGATTATCAACACATTGAATTTCATGCACTTATATGCCGGATAAGACGCGGCTAGCGTCGCA
TCCGGCATTATCACATCAGC

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRGLFPISHPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR

Sequences:

>Translated_281_residues
MRGLFPISHPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR
>Mature_281_residues
MRGLFPISHPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFD
DENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGY
CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
AEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI226510970, Length=251, Percent_Identity=98.406374501992, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1790294, Length=226, Percent_Identity=32.7433628318584, Blast_Score=131, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895 [H]

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 31457; Mature: 31457

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLFPISHPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQ
CCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLD
CCCCEECCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
APFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
CCCCCHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
>Mature Secondary Structure
MRGLFPISHPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLIRRIHAVQGSPCVETCQ
CCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQ
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLD
CCCCEECCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
APFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAV
CCCCCHHHCCCCHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA