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The map label for this gene is ygcS [H]

Identifier: 218690891

GI number: 218690891

Start: 3152327

End: 3153664

Strand: Reverse

Name: ygcS [H]

Synonym: ECED1_3220

Alternate gene names: 218690891

Gene position: 3153664-3152327 (Counterclockwise)

Preceding gene: 218690892

Following gene: 218690890

Centisome position: 60.54

GC content: 53.44

Gene sequence:

>1338_bases
ATGAACACTTCACCGGTGCGAATGGATGATTTACCGCTTAACCGTTTTCACTGTCGAATTGCTGCGCTCACTTTCGGCGC
ACACCTGACCGACGGTTATGTCCTCGGCGTTATTGGTTACGCCATTATTCAGCTTACGCCCGCCATGCAACTGACGCCGT
TTATGGCGGGAATGATCGGCGGCTCGGCGTTACTTGGTTTGTTTCTTGGCAGCCTGGTTTTGGGGTGGATCTCCGACCAT
ATCGGGCGGCAAAAAATCTTCACCTTCAGTTTTATGCTGATTACGCTCGCTTCGTTCTTGCAATTTTTTGCCACCACGCC
AGAGCATCTTATTGGATTGCGCATTTTGATCGGCATTGGTCTGGGAGGCGATTACTCAGTCGGTCACACCTTGCTGGCTG
AATTTTCCCCGCGCCGCCATCGCGGTATTTTGCTGGGCGCATTCAGTGTGGTGTGGACCGTAGGCTATGTGCTGGCAAGT
ATTGCCGGACATCACTTTATTTCCGAAAGCCCGGAGGCCTGGCGCTGGCTGCTGGCATCAGCGGCGTTACCAGCCTTGCT
GATTACGCTGCTACGTTGGGGCACGCCGGAATCGCCACGCTGGCTACTGCGCCAGGGGCGTTTTGCAGAAGCTCACGCTA
TCGTTCATCGCTATTTTGGCCCGCATGTTTTACTGGGCGATGAAGTGGCAACGGCGACCCATAAACACATCAAAACCTTG
TTCTCTTCGCGCTACTGGCGGCGCACGGCGTTTAACAGCGTCTTCTTTGTCTGCCTCGTAATCCCATGGTTTGTGATTTA
TACCTGGTTGCCGACCATCGCCCAAACTATTGGTCTGGAAGATGCGCTGACTGCCAGCCTGATGCTTAATGCGTTGTTAA
TTGTTGGCGCGTTATTAGGGTTAGTGTTGACCCACTTGTTAGCGCATCGCAGATTTTTACTGGGAAGTTTTTTGCTGCTA
ACGGCAACGCTGGTAGTAATGGCCTGTTTGCCTTCCGGCAGTTCATTAACGCTGCTGCTTTTTGTTCTCTTCAGCACCAC
CATTTCGGCAGTCAGTAATCTGGTGGGCATTTTGCCTGCGGAAAGTTTTCCTACTGACATTCGCTCGCTGGGCGTCGGTT
TTGCCACCGCCATGAGTCGGTTGGGGGCGGCGGTAAGTACTGGCCTGCTGCCGTGGGTGCTGGCGCAGTGGGGAATGCAA
GCCACCTTATTGCTCCTGGCGGCAGTGTTGTTGGTTGGTTTTGTTGTGACCTGGCTATGGGCACCAGAAACCAAAGCACT
CCCGCTGGTGGCGGCGGGAAATGTAGGAGGTGCGAATGAACATTCTGTTAGCGTTTAA

Upstream 100 bases:

>100_bases
AAAATAATGTGTCAGGCAGCGTTCCGCGATGACGGGGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTAC
CGGACAATGAAGGGGTAAAG

Downstream 100 bases:

>100_bases
AGCCGAACCGGATGCCGGAATGCTGGCGGAAAAAGAGTGGCAGGCGGCTCAGGGTAATAGCGGACCGGATGTTTCGCTTC
TGCGAAGTTTACTCGGTGCC

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRRFLLGSFLLL
TATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Sequences:

>Translated_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRRFLLGSFLLL
TATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>Mature_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISESPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRRFLLGSFLLL
TATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507005, Length=394, Percent_Identity=26.1421319796954, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI302148518, Length=365, Percent_Identity=25.4794520547945, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4506999, Length=426, Percent_Identity=26.056338028169, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI24497490, Length=334, Percent_Identity=26.3473053892216, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI166197673, Length=365, Percent_Identity=27.9452054794521, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI24308167, Length=446, Percent_Identity=23.7668161434978, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI23510410, Length=357, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI296080721, Length=217, Percent_Identity=30.8755760368664, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI296080734, Length=217, Percent_Identity=30.8755760368664, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI7662270, Length=211, Percent_Identity=27.4881516587678, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI90669191, Length=347, Percent_Identity=27.3775216138329, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI296080719, Length=347, Percent_Identity=26.8011527377522, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497499, Length=347, Percent_Identity=26.8011527377522, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497497, Length=347, Percent_Identity=27.3775216138329, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI213021148, Length=415, Percent_Identity=24.8192771084337, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21553331, Length=312, Percent_Identity=23.7179487179487, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI8923870, Length=382, Percent_Identity=24.6073298429319, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI203098995, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI166064021, Length=330, Percent_Identity=24.5454545454545, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI11415038, Length=374, Percent_Identity=24.331550802139, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082159, Length=445, Percent_Identity=98.4269662921348, Blast_Score=862, Evalue=0.0,
Organism=Escherichia coli, GI1786229, Length=431, Percent_Identity=34.8027842227378, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1788074, Length=418, Percent_Identity=26.0765550239234, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788068, Length=451, Percent_Identity=24.6119733924612, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789207, Length=208, Percent_Identity=32.2115384615385, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790463, Length=207, Percent_Identity=27.0531400966184, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789312, Length=436, Percent_Identity=24.3119266055046, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=21.9753086419753, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082231, Length=412, Percent_Identity=23.0582524271845, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17556354, Length=408, Percent_Identity=26.9607843137255, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565976, Length=154, Percent_Identity=29.8701298701299, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988651, Length=156, Percent_Identity=35.2564102564103, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565978, Length=327, Percent_Identity=24.4648318042813, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564080, Length=408, Percent_Identity=24.7549019607843, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560496, Length=398, Percent_Identity=23.8693467336683, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209824, Length=390, Percent_Identity=25.3846153846154, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145172, Length=398, Percent_Identity=24.1206030150754, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324469, Length=458, Percent_Identity=20.9606986899563, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649618, Length=339, Percent_Identity=26.2536873156342, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19922616, Length=394, Percent_Identity=24.8730964467005, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24649622, Length=387, Percent_Identity=24.2894056847545, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24668440, Length=406, Percent_Identity=23.8916256157635, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24668456, Length=408, Percent_Identity=25, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640198, Length=438, Percent_Identity=23.972602739726, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640196, Length=438, Percent_Identity=23.972602739726, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640200, Length=438, Percent_Identity=23.972602739726, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922874, Length=406, Percent_Identity=25.1231527093596, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649616, Length=359, Percent_Identity=25.6267409470752, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077756, Length=455, Percent_Identity=23.956043956044, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161078338, Length=399, Percent_Identity=25.31328320802, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647365, Length=330, Percent_Identity=24.8484848484848, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48198; Mature: 48198

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRRFLLGSFLLLTATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRRFLLGSFLLLTATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]