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The map label for this gene is hycA [H]

Identifier: 218690849

GI number: 218690849

Start: 3112686

End: 3113147

Strand: Reverse

Name: hycA [H]

Synonym: ECED1_3176

Alternate gene names: 218690849

Gene position: 3113147-3112686 (Counterclockwise)

Preceding gene: 218690857

Following gene: 218690848

Centisome position: 59.76

GC content: 49.78

Gene sequence:

>462_bases
ATGACTATTTGGGAAATAAGCGAGAAAGCCGATTACATCGCACAGCGGCATCGTCGCCTACAGGACCAGTGGCACATCTA
CTGCAATTCGCTGGTTCAGGGGATCACGTTATCGAAAGCGCGCCTGCATCACGCCATGAGCTGCGCGCCGGACAAAGAAC
TCTGTTTCGTCCTTTTTGAACATTTTCGCATTTACGTCACCCTGGCGGATGGCTTTAACAGCCACACCATCGAGTATTAC
GTCGAAACAAAAGATGGCGAAGACAAACAGCGGATTGCGCAGGCGCAGTTGAGCATTGACGGCATGATTGATGGCAAGGT
CAACATCCGCGATCGCGAACAAGTTCTGGAACACTATCTCGAAAAAATCGCTGGCGTTTACGACAGCTTATATACCGCCA
TTGAAAACAATGTGCCGGTGAATTTAAGCCAACTGGTAAAGGGACAAAGCCCGGTAGCATGA

Upstream 100 bases:

>100_bases
AATTCATCTTTAGCTTAGAAATCGCTTTAATAACAATGAATTAAAAGTTGGCACAGAAAATGCCTAAAGCTGGCATCTCT
GTTAAACGGGTAACCTGACA

Downstream 100 bases:

>100_bases
GCTGAGGCTTTGCCCGTTTTGCAGGCGTTACGCCTGTTTGGGGATGGGCGTGTCGATGAGTGTCGAAAATGACATTTCAT
CGGCATGTTTTCGTCAAAAA

Product: formate hydrogenlyase regulatory protein HycA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYY
VETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA

Sequences:

>Translated_153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYY
VETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA
>Mature_152_residues
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYV
ETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA

Specific function: Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with fhlA or by preventing the binding of fhlA to the upstream activatory sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789080, Length=153, Percent_Identity=99.3464052287582, Blast_Score=320, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021285 [H]

Pfam domain/function: PF11046 HycA_repressor [H]

EC number: NA

Molecular weight: Translated: 17655; Mature: 17524

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFE
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYL
HHEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEECCEECCCCHHHHHHHHH
EKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFE
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYL
HHEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCEEECCEECCCCHHHHHHHHH
EKIAGVYDSLYTAIENNVPVNLSQLVKGQSPVA
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]