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The map label for this gene is eutG [H]

Identifier: 218690579

GI number: 218690579

Start: 2832592

End: 2833779

Strand: Reverse

Name: eutG [H]

Synonym: ECED1_2886

Alternate gene names: 218690579

Gene position: 2833779-2832592 (Counterclockwise)

Preceding gene: 218690580

Following gene: 218690578

Centisome position: 54.4

GC content: 58.75

Gene sequence:

>1188_bases
ATGCAAAGTGAATTGCAAACGGCGCTTTTTCAGGCGTTCGATACCCTGAATCTGCAACGGGTAAAAACATTTAGCGTTCC
ACCGGTGACGCTTTGCGGTCCGGGCACGGTGAGCAGTTGCGGGCAGCAAGCGCAAACGCGTGGGTTGAAACATCTGTTCG
TGATGGCAGACAGCTTTTTGCATCAGGCAGGGATGACCGCCGGGCTGACACGTAGCCTGGCCGTTAAAGGTATCGCCATG
ACGCTCTGGCCATGTCCGGTGGGCGAACCGTGCATCACCGACGTGTGTGCAGCCGTGGCGCAGTTGCGTGAATCAGGTTG
TGACGGGGTGATCGCGTTTGGCGGCGGCTCGGTGCTGGATGCGGCGAAAGCCGTGGCGTTGCTGGTGACGAACCCGGATA
GCACGCTGGCAGAAATGTCAGAAACCAGCGTTCTGCAACCGCGCCTGCCGTTGATTGCCATTCCAACGACCGCCGGAACC
GGCTCTGAAACGACTAACGTGACGGTGATTATCGATGCGGTAAGCGGGCGCAAACAGGTGTTAGCCCACGCCTCGCTGAT
GCCGGATGTGGCGATTCTCGACGCTGTGCTGACCGAAGGCGTGCCGTCGCATGTCACGGCGATGACTGGCATTGATGCGT
TAACCCATGCCATTGAAGCGTACAGCGCGCTGAACGCTACACCGTTTACCGACAGCCTGGCGATTGGTGCCATTGCGATG
ATTGGCAAATCACTGCCGAAAGCGGTGGGCTACGGCCATGACCTTGCCGCGCGCGAGAGCATGTTGCTGGCTTCATGTAT
GGCGGGAATGGCGTTTTCCAGCGCCGGGCTTGGGTTATGCCACGCGATGGCGCATCAGCCAGGGGCGGCGCTGCATATTC
CGCACGGTCTGGCGAACGCCATGTTGCTGCCAACGGTGATGGAGTTTAACCGGATGGTTTGTCGTGATCGGTTTAGTCAG
ATTGGTCGGGCGCTGCGAACTAAAAAATCCGACGATCGTGACGCTATTAATGCGGTAAGTGAGCTGATAGCGGAAGTTGG
GATCAACAAGCGGCTGGCTGATGTGGGTGCAACAACCGGGCATTACGGTGCATGGGCGCAGGCCGCGCAGGAAGATATTT
GTCTGCGCAGCAACCCGCGTACCGCCAGCCTGGAGCAGATTGTCGGCCTGTACGCAGCGGCGCAATAA

Upstream 100 bases:

>100_bases
AAACAATTTCCGGCGTTACAGGTGCATTTACCGCAGCACAGTTTGTTTATGACCCCGCTGGCAATCGCCAGTAGTGGGCG
AGAGAAAGCGGAGGGGATCT

Downstream 100 bases:

>100_bases
ATGCCGGATGCGACGCTTGCCGCGTCTTATCCGGCCTACGGGATTGCACATGTAGGGCGGATAAGGCGTTCACGCCGCAT
CCGCCAGTGGCGCGGTGCAA

Product: putative alcohol dehydrogenase in ethanolamine utilization; ethanolaminosome

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQSELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGTVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGINKRLADVGATTGHYGAWAQAAQEDICLRSNPRTASLEQIVGLYAAAQ

Sequences:

>Translated_395_residues
MQSELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGTVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGINKRLADVGATTGHYGAWAQAAQEDICLRSNPRTASLEQIVGLYAAAQ
>Mature_395_residues
MQSELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGTVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQ
IGRALRTKKSDDRDAINAVSELIAEVGINKRLADVGATTGHYGAWAQAAQEDICLRSNPRTASLEQIVGLYAAAQ

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=26.4705882352941, Blast_Score=112, Evalue=8e-25,
Organism=Escherichia coli, GI87082107, Length=395, Percent_Identity=97.2151898734177, Blast_Score=784, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=36.7724867724868, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=39.247311827957, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787493, Length=383, Percent_Identity=32.1148825065274, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1789386, Length=284, Percent_Identity=26.7605633802817, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=405, Percent_Identity=25.9259259259259, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=380, Percent_Identity=33.6842105263158, Blast_Score=212, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24657991, Length=405, Percent_Identity=28.1481481481481, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 41059; Mature: 41059

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGTVSSCGQQAQTRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRDAINAVSELIAEVGINKRLADVGATTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC
HYGAWAQAAQEDICLRSNPRTASLEQIVGLYAAAQ
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGTVSSCGQQAQTRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAVLTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRDAINAVSELIAEVGINKRLADVGATTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC
HYGAWAQAAQEDICLRSNPRTASLEQIVGLYAAAQ
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]