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The map label for this gene is ompC [H]

Identifier: 218690378

GI number: 218690378

Start: 2602121

End: 2603248

Strand: Reverse

Name: ompC [H]

Synonym: ECED1_2681

Alternate gene names: 218690378

Gene position: 2603248-2602121 (Counterclockwise)

Preceding gene: 218690381

Following gene: 218690377

Centisome position: 49.97

GC content: 50.89

Gene sequence:

>1128_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTCCCAGCTCTGCTGGTAGCAGGCGCAGCAAACGCTGCTGAAGTTTACAATAA
AGACGGCAACAAATTAGATCTGTACGGTAAAGTAGACGGCCTGCACTATTTCTCTGACAACAAGTCAGAAGATGGCGACC
AGACCTACATGCGTCTTGGTTTCAAAGGCGAAACTCAGGTTACTGACCAACTGACTGGTTACGGCCAGTGGGAATATCAG
ATCCAGGGCAACGCTCCGGAAAGCGAAAACAACTCCTGGACCCGTGTGGCATTTGCTGGTCTGAAATTCCAGGACATCGG
TTCTTTCGACTACGGTCGTAACTACGGCGTTGTTTACGACGTAACTTCCTGGACCGACGTTCTGCCAGAATTCGGTGGCG
ACACCTACGGTTCTGACAACTTCATGCAGCAGCGTGGTAACGGCTTCGCGACCTACCGTAACACCGACTTCTTCGGTCTG
GTTGACGGCCTGAACTTTGCTGTTCAGTACCAGGGCCAGAATGGCAGCGTAAGCGGTGAAAATGATCCGGATTTCACTGG
TCATGGCATCACCAACAATGGTCGTAAAGCTCTGCGTCAGAACGGCGACGGTGTCGGCGGATCTATCACTTATGATTACG
AAGGCTTCGGCGTTGGTGCTGCAGTTTCCAGCTCCAAACGTACCTGGGATCAGAACAACACTGGCCTGATCGGTACTGGC
GACCGTGCTGAAACCTACACTGGTGGTCTGAAATACGACGCTAACAACATCTACCTGGCTGCTCAGTACACCCAGACCTA
CAACGCAACTCGCGTAGGTTCCCTGGGTTGGGCGAACAAAGCACAGAACTTCGAAGCTGTTGCTCAGTACCAGTTCGACT
TTGGTCTGCGTCCGTCTGTAGCATACCTGCAGTCTAAAGGTAAAAACCTGGGTGTCGTTGCTGGTCGTAACTACGACGAC
GAAGATATCCTGAAATATGTTGATGTTGGTGCTACCTACTACTTCAACAAAAACATGTCCACCTACGTTGACTACAAAAT
CAACCTGCTGGACGACAACCAGTTCACCCGCGCTGCTGGCATCAACACTGATGACATCGTAGCTCTGGGTCTGGTTTACC
AGTTCTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAATGGACTTGCCGACTGATTAATGAGGGTTAATCAGTATGCAGTGGCATAAAAAAGCAAATAAAGGCA
TATAACAGAGGGTTAATAAC

Downstream 100 bases:

>100_bases
TCTCGATTTATATCGAACAAAGGGCCTGCGGGCCCTTTTTTCATTGTTTTCAGCGTACAAACACAGTTTTTTGGTGTACT
CTTGCGACCGTTCGCATGAG

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTG
DRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDD
EDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF

Sequences:

>Translated_375_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTG
DRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDD
EDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF
>Mature_375_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYMRLGFKGETQVTDQLTGYGQWEYQ
IQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
VDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTG
DRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDD
EDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=375, Percent_Identity=90.6666666666667, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=385, Percent_Identity=67.5324675324675, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1786436, Length=380, Percent_Identity=56.578947368421, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1787160, Length=389, Percent_Identity=57.5835475578406, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 41254; Mature: 41254

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
NDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTG
CCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCEEEECC
DRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSV
CCCCEECCCEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCH
AYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAG
HHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCEEEECC
INTDDIVALGLVYQF
CCCCCEEEEEEEECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYMRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEC
FKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYD
CCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEEE
VTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVSGE
CCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCCC
NDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTG
CCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCCCEEEECC
DRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSV
CCCCEECCCEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCH
AYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAG
HHHHHCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCEEEECC
INTDDIVALGLVYQF
CCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]