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The map label for this gene is ccmB [H]

Identifier: 218690362

GI number: 218690362

Start: 2587402

End: 2588064

Strand: Reverse

Name: ccmB [H]

Synonym: ECED1_2665

Alternate gene names: 218690362

Gene position: 2588064-2587402 (Counterclockwise)

Preceding gene: 218690363

Following gene: 218690361

Centisome position: 49.68

GC content: 56.11

Gene sequence:

>663_bases
ATGATGTTCTGGCGCATTTTCCGTCTTGAGCTGCGCGTAGCGTTTCGCCATAGCGCCGAAATCGCCAACCCGCTGTGGTT
CTTCCTGATTGTAATTACCCTTTTTCCGCTCAGTATCGGTCCGGAGCCGCAACTGCTGGCGCGTATTGCGCCGGGCATTA
TCTGGGTTGCCGCGCTGCTTTCATCCTTGCTGGCACTCGAGCGACTGTTCCGTGACGATTTGCAGGACGGCAGTCTTGAA
CAATTGATGTTGTTGCCGTTACCCTTGCCCGCCGCTGTGCTGGCGAAGGTGATGGCGCACTGGATGGTAACCGGTCTGCC
GTTACTCATCCTTTCGCCCCTGGTAGCAATGCTACTGGGAATGGATGTTTATGGCTGGCAAGTGATGGCGTTAACGCTAC
TGCTGGGAACCCCTACGCTTGGCTTTCTTGGTGCGCCGGGCGTGGCGCTGACAGTGGGACTTAAGCGCGGTGGTGTGCTG
CTCAGCATACTGGTGTTACCGCTGACTATCCCATTACTCATCTTTGCCACCGCCGCGATGGACGCGGCTTCTATGCATTT
GCCCGTTGATGGGTATCTGGCAATTTTAGGCGCGTTGCTGGCAGGCACCGCGACATTAAGTCCTTTTGCGACGGCGGCAG
CGTTACGAATCAGCATTCAATAA

Upstream 100 bases:

>100_bases
ATACGGAGCAGGGGGGGATTGTGATTCTGACTACCCACCAGCCGCTCAACGTTGCTGAAAGTAAAATTCGCCGCATTTCA
CTGACGCAAACGGGGGCCGC

Downstream 100 bases:

>100_bases
CGCTGGATTACTGATTTTTGTTCGAGTCTGGTATCGAAACTATGTGGAAAACACTGCATCAACTGGCGATCCCACCACGG
CTGTATCAAATCTGTGGCTG

Product: heme ABC transporter membrane protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLE
QLMLLPLPLPAAVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ

Sequences:

>Translated_220_residues
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLE
QLMLLPLPLPAAVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
>Mature_220_residues
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLE
QLMLLPLPLPAAVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=220, Percent_Identity=99.5454545454545, Blast_Score=413, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23591; Mature: 23591

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SSLLALERLFRDDLQDGSLEQLMLLPLPLPAAVLAKVMAHWMVTGLPLLILSPLVAMLLG
HHHHHHHHHHHHCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
MDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVLLSILVLPLTIPLLIFATAAM
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHEEECC
>Mature Secondary Structure
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SSLLALERLFRDDLQDGSLEQLMLLPLPLPAAVLAKVMAHWMVTGLPLLILSPLVAMLLG
HHHHHHHHHHHHCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
MDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVLLSILVLPLTIPLLIFATAAM
CCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]