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The map label for this gene is chbR [H]

Identifier: 218689676

GI number: 218689676

Start: 1894577

End: 1895419

Strand: Reverse

Name: chbR [H]

Synonym: ECED1_1937

Alternate gene names: 218689676

Gene position: 1895419-1894577 (Counterclockwise)

Preceding gene: 218689677

Following gene: 218689675

Centisome position: 36.38

GC content: 41.04

Gene sequence:

>843_bases
ATGATGCAGCCAGTGATTAACGCGCCGGAAATTGCCACTGCCCGAGAACAGCAGTTGTTTAATGGCAAAAACTTCCATGT
GTTTATCTACAATAAAACTGAGAGTATCAGCGGACTGCATCAGCACGACTATTATGAATTTACTCTGGTATTAACCGGGC
GTTATTTCCAGGAGATTAACGGTAAGCGCGTGTTACTGGAACGGGGCGATTTTGTTTTTATTCCGTTAGGTTCGCACCAT
CAAAGTTTTTATGAATTTGGTGCCACGCGTATATTGAACGTTGGGATCAGTAAACGCTTTTTTGAGCAGCATTACCTGCC
GTTGTTGCCTTATTGCTTTGTAGCTTCGCAGGTATACCGGACCAATAACGCTTTTCTCACCTATGTGGAAACAGTGATTT
CTTCATTGAATTTCCGCGAAACAGGGCTGGAAGAGTTTGTTGAGATGGTTACTTTTTATGTCATTAACCGTTTACGTCAT
TACCGCGAAGAACAGGTGATTGATGATATACCGCAGTGGCTGAAAAGTACGGTAGAAAAGATGCATGATAAAGAGCAGTT
TAGTGAATCGGCGCTGGAGAATATGGTGACGTTGTCAGCCAAATCACAGGAATATTTGACGCGAGCGACTCAACGATACT
ATGGTAAAACGCCAATGCAGATTATTAATGAAATCCGTATTAATTTTGCCAAAAAACAACTGGAAATGACCAACTATTCA
GTGACGGATATTGCGTTTGAGGCCGGTTATAGTAGCCCGAGCTTGTTTATTAAAACGTTTAAGAAATTAACATCCTTTAC
GCCTAAGAGCTATCGTAAGAAATTGACTGAATTTAATCAGTAA

Upstream 100 bases:

>100_bases
CTAGTCCACGCTCAGGATCATTTAATGACGTCCATGCTTGCGCGTGAACTGATTACTGAATTAATTGAGCTTCATGAAAA
ACTGAAGGCATAAGGAGTCG

Downstream 100 bases:

>100_bases
GTCGTTATACCTGACAATTCACATATCTGTCCTGTTGCTGGATTATTTATGTCCGGGGGGCAGATATGCCAGATATCAGT
ATTCTGTACTGAAGGGAGAA

Product: DNA-binding transcriptional regulator ChbR

Products: NA

Alternate protein names: Chb operon repressor [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHH
QSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
YREEQVIDDIPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYS
VTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ

Sequences:

>Translated_280_residues
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHH
QSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
YREEQVIDDIPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYS
VTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
>Mature_280_residues
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHH
QSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
YREEQVIDDIPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYS
VTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ

Specific function: Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presen

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788030, Length=280, Percent_Identity=99.2857142857143, Blast_Score=577, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013096
- InterPro:   IPR011051
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF07883 Cupin_2; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33012; Mature: 33012

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEIN
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHCCCHHCCCEEEEEEEEHHHHHHCC
GKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYR
CCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHH
TNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHYREEQVIDDIPQWLKSTVEK
CCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
HHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEIN
CCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHCCCHHCCCEEEEEEEEHHHHHHCC
GKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYR
CCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHH
TNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHYREEQVIDDIPQWLKSTVEK
CCCHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
VTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
HHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 9405618 [H]