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The map label for this gene is celA [H]

Identifier: 218689423

GI number: 218689423

Start: 1645914

End: 1647383

Strand: Reverse

Name: celA [H]

Synonym: ECED1_1661

Alternate gene names: 218689423

Gene position: 1647383-1645914 (Counterclockwise)

Preceding gene: 218689424

Following gene: 218689419

Centisome position: 31.62

GC content: 44.29

Gene sequence:

>1470_bases
GTGGTAATCTATTTAGTTAAGGAGTTGTGTATGTCAGGATTTAAAGAAGATTTTTTATGGGGCGGTGCGGTAGCCGCACA
TCAATTGGAAGGTGGCTGGAATGAAGGAGGAAAAGGCATCAGTATCGCTGATGTAATGACTGCTGGCGCTCACGGGGTGC
CGCGTGAAGTGACAGAAGGCGTTATCGACGGACTTAATTATCCCAATCATGAAGCAATTGATTTTTATCATCGCTATAAA
ACAGATATTCAGTTATTTGCCGGGATGGGATTCAAATGCTTTCGAACTTCCATTGCCTGGACACGAATCTTTCCGCAAGG
TGACGAACAGGAGCCGAATGAAGAGGGTTTACAATTTTATGATGATCTCTTCGATGAATGCCTGAAGCAGGGAATGGAAC
CTGTGGTGACGCTTTCGCATTTTGAGATGCCTTATCATCTGGTGACAAAATATGGTGGCTGGCGAAACCGTAAACTGATC
GACTTTTTTATCCACTTCGCATCAACGGTCTTCACGCGCTATAAAGAAAAAGTAAAGTACTGGATGACGTTTAACGAAAT
CAATAATCAGGTGAATTTCAGCGAAAGCCTGTGTCCATTTACTAATTCCGGTATCTTGTATTCGCCAGAGGAAGATCTCA
ATGAGCGCGAACAAATAATGTACCAGGCGGTACATTATGAGTTAGTTGCCAGTGCCCTGGCGGTACAGACTGGAAAACTG
ATCAATCCTGAATTTAATATCGGCTGTATGATTGCTATGTGCCCCATCTATCCTCTGACGTGTGCACCCAACGATATGAT
GATGGCCACGAAAGCGATGCATCGTCGTTACTGGTTTACTGATGTTCATGCTCGTGGATATTATCCGCAACATATGCTGA
ATTACTTTGCAAGGAAAGGATTCAACCTCGATATCACACCAGATGATAACGCGATTCTTGCCAGAGGTTGTGTCGACTTT
ATCGGCTTTAGCTACTACATGTCTTTTACGACGCAATTTTCGCCAGATAATCCGCAACTGGATTATGTTGAACCACGAGA
TTTGGTCAGCAACCCTTATATCGATACATCCGAATGGGGATGGCAAATTGATCCGGCAGGGCTACGTTATTCACTCAACT
GGTTCTGGGATCATTTCCAGTTGCCGCTGTTTATTGTCGAAAATGGATTTGGTGCGGTTGACCAGAGACAAGCTGACGGC
ACGGTGAACGATCACTATCGCATTGATTACTTTTCCTCCCATATTCGGGAAATGAAAAAAGCCGTAGTTGAAGATGGTGT
TGACTTAATTGGCTACACCCCGTGGGGTTGCATTGACCTGGTTTCTGCCGGAACAGGAGAAATGAAAAAACGCTACGGAA
TGATTTATGTCGATAAAGACAACGAAGGGAAGGGAACGCTGGAACGGATACGTAAAGCATCGTTTTACTGGTATCGGGAT
CTCATCGCCAACAATGGCGAAAATATATGA

Upstream 100 bases:

>100_bases
ATCCTCAATGAATCGCAGTCTCTTTATGTAATAAACCTGCTCACCAGTCACTAAATTCAGCTCAGTCGCAATTTATGGCC
GGCATCCAGGCGGAAGTCTG

Downstream 100 bases:

>100_bases
GACTTCAGGAAGATATTACGGAAATGTCAGGCTCTGTGATCAGAGCCTGACAATAACTACATAGCGTGTTGATTATAATA
GGGCACGCCGAGCGCATCCG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MVIYLVKELCMSGFKEDFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYK
TDIQLFAGMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLI
DFFIHFASTVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDLNEREQIMYQAVHYELVASALAVQTGKL
INPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPDDNAILARGCVDF
IGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADG
TVNDHYRIDYFSSHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRD
LIANNGENI

Sequences:

>Translated_489_residues
MVIYLVKELCMSGFKEDFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYK
TDIQLFAGMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLI
DFFIHFASTVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDLNEREQIMYQAVHYELVASALAVQTGKL
INPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPDDNAILARGCVDF
IGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADG
TVNDHYRIDYFSSHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRD
LIANNGENI
>Mature_489_residues
MVIYLVKELCMSGFKEDFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEGVIDGLNYPNHEAIDFYHRYK
TDIQLFAGMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLI
DFFIHFASTVFTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDLNEREQIMYQAVHYELVASALAVQTGKL
INPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKGFNLDITPDDNAILARGCVDF
IGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADG
TVNDHYRIDYFSSHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRD
LIANNGENI

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=497, Percent_Identity=28.5714285714286, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI32481206, Length=493, Percent_Identity=27.1805273833671, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI24497614, Length=499, Percent_Identity=29.2585170340681, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI13273313, Length=492, Percent_Identity=25.609756097561, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI28376633, Length=485, Percent_Identity=26.5979381443299, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI2367174, Length=486, Percent_Identity=59.0534979423868, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=48.6542443064182, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI2367270, Length=479, Percent_Identity=50.1043841336117, Blast_Score=467, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17552856, Length=489, Percent_Identity=28.0163599182004, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=27.2540983606557, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356577, Length=489, Percent_Identity=28.2208588957055, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 56445; Mature: 56445

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIYLVKELCMSGFKEDFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEG
CEEHHHHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHH
VIDGLNYPNHEAIDFYHRYKTDIQLFAGMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFY
HHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHEEEECCCCCCCCCCHHHHHHH
DDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIHFASTVFTRYKEKVKY
HHHHHHHHHHCCCCEEEHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WMTFNEINNQVNFSESLCPFTNSGILYSPEEDLNEREQIMYQAVHYELVASALAVQTGKL
EEEHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKG
CCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCC
FNLDITPDDNAILARGCVDFIGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWG
CCEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
WQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRIDYFSSHIREMKK
CEECCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHH
AVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRD
HHHHCCCCEECCCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LIANNGENI
HHHCCCCCC
>Mature Secondary Structure
MVIYLVKELCMSGFKEDFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVPREVTEG
CEEHHHHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHH
VIDGLNYPNHEAIDFYHRYKTDIQLFAGMGFKCFRTSIAWTRIFPQGDEQEPNEEGLQFY
HHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHEEEECCCCCCCCCCHHHHHHH
DDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIHFASTVFTRYKEKVKY
HHHHHHHHHHCCCCEEEHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WMTFNEINNQVNFSESLCPFTNSGILYSPEEDLNEREQIMYQAVHYELVASALAVQTGKL
EEEHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARGYYPQHMLNYFARKG
CCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCC
FNLDITPDDNAILARGCVDFIGFSYYMSFTTQFSPDNPQLDYVEPRDLVSNPYIDTSEWG
CCEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCC
WQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTVNDHYRIDYFSSHIREMKK
CEECCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHH
AVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKDNEGKGTLERIRKASFYWYRD
HHHHCCCCEECCCCCCHHHHHCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LIANNGENI
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]