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The map label for this gene is yliI [H]

Identifier: 218688620

GI number: 218688620

Start: 835763

End: 836878

Strand: Direct

Name: yliI [H]

Synonym: ECED1_0801

Alternate gene names: 218688620

Gene position: 835763-836878 (Clockwise)

Preceding gene: 218688619

Following gene: 218688622

Centisome position: 16.04

GC content: 51.61

Gene sequence:

>1116_bases
ATGCATCGACAATCCTTTTTCCTTGTGCCCCTTATTTGTCTTTCTTCCGCTCTCTGGGCAGCTCCTGCAACGGTAAATGT
CGAAGTACTGCAAGACAAACTCGACCATCCCTGGGCGCTGGCCTTTTTACCCGATAATCACGGTATGTTAATCACTCTGC
GCGGCGGCGAGTTGCGTCACTGGCAAGCAGGAAAAGGATTATCTGCGCCGCTTTCCGGAGTGCCGGACGTTTGGGCGCAC
GGGCAGGGCGGCCTGCTGGACGTGGTTTTAGCGCCCGATTTTGCTCAGTCGCGCCGCATCTGGTTAAGTTATTCCGAAGT
TGGCGATGATGGCAAAGCCGGAACTGCTGTGGGTTATGGCCGCTTAAGTGATGATCTCTCAAAAGTGACCGACTTCCGCA
CCGTCTTTCGTCAGATGCCAAAACTGTCTACCGGTAACCATTTTGGCGGGCGGATGGTATTCGACGGTAAAGGTTATCTT
TTTATTGCTCTGGGCGAAAACAATCAGCGCCCGACGGCGCAGGATCTGGATAAATTACAGGGCAAACTGGTGCGTCTGAC
CGACCTGGGAGAAATCCCGGATGATAATCCTTTTATAAAGGAATCCGGTGTGCGCGCCGAGATCTGGTCTTATGGCATTC
GTAATCCGCAAGGAATGGCGATGAATCCGTGGAGTAATGCACTATGGCTGAATGAACATGGCCCGCGCGGTGGTGATGAA
ATTAATATTCCGCAAAAAGGCAAAAACTACGGCTGGCCGCTGGCAACCTGGGGAATCAACTATTCGGGCTTTAAGATACC
GGAAGCGAAAGGGGAGATCGTCGCCGGGACCGAGCAACCTGTTTTTTACTGGAAAGATTCGCCCGCCGTGAGCGGCATGG
CCTTCTATAACAGCGACAAATTCCCCCAGTGGCAGCAAAAATTATTTATTGGCGCGCTGAAAGATAAAGATGTCATTGTG
ATGAGCGTCAACGGCGACAAAGTGACAGAAGATGGCCGTATTTTAACGGACAGAGGGCAGCGAATTCGTGATGTTCGCAC
TGGACCCGACGGTTATTTATACGTTCTCACCGACGAGTCCAGTGGGGAATTACTTAAAGTTAGCCCACGCAATTAG

Upstream 100 bases:

>100_bases
GGAGAAAGCGTCTCCCCCTTCATGTTTAAGTTTTTGTAAAAATGAATTTGTTATCTCCTCCACTGACTACGCTTTAAGCC
AGAGTCAATCCGGAGGCGTT

Downstream 100 bases:

>100_bases
CTAACGGGAATCATCACCACTTTGCGCACTGCGGGGCGTTCAGTGAGTTGCTGATACCAGCGTTGCAGATTTGGACGCGG
TGTCCAGGTCAGGCCAACGT

Product: PQQ-dependent aldose sugar dehydrogenase (asd)

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN

Sequences:

>Translated_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN
>Mature_371_residues
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=323, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI187936955, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI124248546, Length=200, Percent_Identity=25.5, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787060, Length=371, Percent_Identity=99.1913746630728, Blast_Score=753, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 41086; Mature: 41086

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEEECCCCCCCCCCCCCCCCEEEEHHCCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCCEEHHHCCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC
>Mature Secondary Structure
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
CCCCCEEHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEECCCCEEEEEECCCEEE
WQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
EECCCCCCCCCCCCCCHHCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCCEEECC
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYLFIALGENNQRPTAQDLDKLQ
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHC
GKLVRLTDLGEIPDDNPFIKESGVRAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
CEEEEEEECCCCCCCCCCCCCCCCEEEEHHCCCCCCCCCEECCCCCEEEEECCCCCCCCE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
ECCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEECCCCCCCEEEEECCCC
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDES
CCHHHHHHEEEEECCCCEEEEEECCCEECCCCEEEECCCCEEHHHCCCCCCEEEEEEECC
SGELLKVSPRN
CCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]