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The map label for this gene is deoK [H]

Identifier: 218688172

GI number: 218688172

Start: 341734

End: 342750

Strand: Reverse

Name: deoK [H]

Synonym: ECED1_0326

Alternate gene names: 218688172

Gene position: 342750-341734 (Counterclockwise)

Preceding gene: 218688183

Following gene: 218688171

Centisome position: 6.58

GC content: 39.33

Gene sequence:

>1017_bases
GTGCTAATCGCGATCTCAGTCACAAATGATGCAAAAGTAACATACCAATGTTATTTAAATACCATTGTTATGCGAAAGTT
TATAAGAGGTAGTGAAATGGACATTGCAGTTATTGGTTCCAATATGGTGGATCTCATTACTTACACTAATCAGATGCCTA
AAGAAGGAGAAACTCTGGAAGCACCTGCCTTCAAAATCGGATGTGGTGGGAAAGGTGCTAATCAAGCGGTGGCGGCGGCT
AAATTGAATTCAAAAGTCCTGATGCTGACTAAAGTAGGTGATGATATTTTTGCGGATAATACTATTCGTAATCTTGAATC
TTGGGGAATTAATACCACTTATGTTGAGAAAGTCCCCTGTACCAGCAGTGGTGTTGCGCCGATCTTTGTTAATGCTAACT
CGAGCAATAGTATTTTAATAATTAAGGGGGCGAATAAATTTCTTTCCCCGGAAGATATCGATCGAGCTGCAGAAGATCTG
AAAAAATGCAAATTGATCGTTTTACAACTGGAAGTTCAACTGGAAACAGTTTACCACGCGATTGAGTTTGGTAAGAAAAA
TGGTATTGAAGTGTTATTAAATCCGGCTCCGGCATTGCGTGAGTTAGATATGTCTTATGCCTGCAAATATGATTTCTTTA
TCCCAAATGAAACAGAACTGGAAATATTAACCGGTATGTCGGTTGATACTTATGATCATATTCGTTTGGCCGCACGTTCG
TTAGTTGATAAAGGGCTGAACAATATTATTGTTACCATGAGCGAAAAAGGCGCATTATGGATGACCCGTGATCAGGAAGT
CCATGTTCCTGCATTCAAAGTAAATGCTGTTGATACTAGTGGCGCTGGTGACGCATTTATTGGTTGCTTTTCCCATTATT
ATGTTCAAAGCGGTGATGTTGAAGCCGCTTTGAAAAAAGCCGCTCTCTTTGCCGCTTTCAGCGTCACAGGGAAAGGTACG
CAATCATCTTATCCGAGTATTGAACAATTTAATGAATTTTTAACCTTAAACGAATAA

Upstream 100 bases:

>100_bases
TGCTGAATTTTCGGTATTAATCCTGTTAGGTTGCTTATGATTAGATAGTGTTGGCCTGAGTGATAAGACTGGAAGTCTAT
TAAATAAACATCGGGTTGAT

Downstream 100 bases:

>100_bases
TCATCCTGCACAGTTAAAGGTAGCACTATGAACGATAAAAACATCATTCAGATGCCTGATGGGTATCTGAATAAGACCCC
CTTGTTCCAGTTTATTTTGT

Product: Deoxyribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLIAISVTNDAKVTYQCYLNTIVMRKFIRGSEMDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAA
KLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDL
KKCKLIVLQLEVQLETVYHAIEFGKKNGIEVLLNPAPALRELDMSYACKYDFFIPNETELEILTGMSVDTYDHIRLAARS
LVDKGLNNIIVTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAALFAAFSVTGKGT
QSSYPSIEQFNEFLTLNE

Sequences:

>Translated_338_residues
MLIAISVTNDAKVTYQCYLNTIVMRKFIRGSEMDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAA
KLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDL
KKCKLIVLQLEVQLETVYHAIEFGKKNGIEVLLNPAPALRELDMSYACKYDFFIPNETELEILTGMSVDTYDHIRLAARS
LVDKGLNNIIVTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAALFAAFSVTGKGT
QSSYPSIEQFNEFLTLNE
>Mature_338_residues
MLIAISVTNDAKVTYQCYLNTIVMRKFIRGSEMDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQAVAAA
KLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDL
KKCKLIVLQLEVQLETVYHAIEFGKKNGIEVLLNPAPALRELDMSYACKYDFFIPNETELEILTGMSVDTYDHIRLAARS
LVDKGLNNIIVTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAALFAAFSVTGKGT
QSSYPSIEQFNEFLTLNE

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=40.2061855670103, Blast_Score=212, Evalue=3e-55,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=36.5448504983389, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=29.2207792207792, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=37.5816993464052, Blast_Score=201, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6319884, Length=326, Percent_Identity=28.5276073619632, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20128807, Length=304, Percent_Identity=35.1973684210526, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24583886, Length=306, Percent_Identity=32.6797385620915, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 36944; Mature: 36944

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAISVTNDAKVTYQCYLNTIVMRKFIRGSEMDIAVIGSNMVDLITYTNQMPKEGETLE
CEEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCEEC
APAFKIGCGGKGANQAVAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPC
CCEEEEECCCCCCCHHEEEEECCCCEEEEEECCCCHHCCCHHHHHHHCCCCCEEEEECCC
TSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHA
CCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHH
IEFGKKNGIEVLLNPAPALRELDMSYACKYDFFIPNETELEILTGMSVDTYDHIRLAARS
HHHCCCCCCEEEECCCCHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHH
LVDKGLNNIIVTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDV
HHHCCCCEEEEEEECCCCEEEECCCEEECCEEEEEEECCCCCCCHHHHHHHHHEEECCCH
EAALKKAALFAAFSVTGKGTQSSYPSIEQFNEFLTLNE
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHEECCC
>Mature Secondary Structure
MLIAISVTNDAKVTYQCYLNTIVMRKFIRGSEMDIAVIGSNMVDLITYTNQMPKEGETLE
CEEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCEEC
APAFKIGCGGKGANQAVAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPC
CCEEEEECCCCCCCHHEEEEECCCCEEEEEECCCCHHCCCHHHHHHHCCCCCEEEEECCC
TSSGVAPIFVNANSSNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHA
CCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHH
IEFGKKNGIEVLLNPAPALRELDMSYACKYDFFIPNETELEILTGMSVDTYDHIRLAARS
HHHCCCCCCEEEECCCCHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHHHHH
LVDKGLNNIIVTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDV
HHHCCCCEEEEEEECCCCEEEECCCEEECCEEEEEEECCCCCCCHHHHHHHHHEEECCCH
EAALKKAALFAAFSVTGKGTQSSYPSIEQFNEFLTLNE
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]