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The map label for this gene is intZ [H]

Identifier: 218551624

GI number: 218551624

Start: 4513203

End: 4514426

Strand: Direct

Name: intZ [H]

Synonym: EFER_4416

Alternate gene names: 218551624

Gene position: 4513203-4514426 (Clockwise)

Preceding gene: 218551623

Following gene: 218551630

Centisome position: 98.35

GC content: 45.1

Gene sequence:

>1224_bases
ATGGCGCTGTCTGATGCGTGGTTGCGTTCAGTCGTTGGAAAGGAACGTGATAAGGTTTTGGTTAAATCCGATCGTGATGG
TCTGTCTGTTAGAGTATCACCGAAAGGTCGCGTAGTGTTCCAATATCGTTATCAGTGGGCGGGGAAAGGTGAGCGTCTTG
ATATCGGAACTTACCCGGCAACTGGACTAAAAGAGGCCAGAGAAGAAGTTATCCGTCTTCGTGGTGAACTCGAGTCAAAC
CGCAATCCACGATTGGTCAAGCAGGCTGAAAAACGAAAAGCTACTGAAGCCATGACGGTAGAGTCTGTGATCCGTGCTTG
GTATGAAGCATATTGTGTAAAAAATAAAAAAGGTTCTGAACAGATACTCCGCTCGTTTGAGCTGCACCTGTTCTCTAAAA
TCGGGAATATCCCTCACGATGCAGCTACATTGCATGATTGGTTAGAAGTCCTGGAGCCTCTTAGCACTAAGACTCCTGCA
ATAGCAGACCGATTGCTAATTAACGCAAAGCAGGCCCACGTCTGGGCGTATAAGAGAAAGCTTATTGAAACTCGCCCGCT
GTCGGATATCACGGGTAAAGATATGGATATCCGTAAAGGTCAGAAGAAACGGTTTCTGACACATGATGAAATTAAAATCC
TTTATGCTGCGATCGATGGTTCTCGAATGGTTCCTAAATACCGGGCCTTCATTAAACTATTGCTGCATTTTGGCTGCCGT
AGTTCAGAGCTAATTACCGCTAGGGTGGATGATTTTGATTTCATTAATAAGGTATGGACTGTACCGCCAGAACGACATAA
GACAGGGGATATAACAGGTGAACCGCTAAAGCGCCCCATTATTGAACCGGTTGAAGAGCTTATAAAGTACGTTATCTCTA
TGAACAATGGTTCCGATATGCTTTTTACTAAGGAAGGATGTAGGGAACCCGTTGGTCGGACATCATTGCAGTCGCTGCCT
TACAATTTAATGCAGTACGCATGGCGGCGTTTAGGGTATCAATTCCCCCATTGGTCTCTTCATGATTTGAGACGAACAGC
ACGAACAAACTTTTCTGATCTTACTGCGCCTCATATTGCAGAAATAATGCTCGGTCATAAACTGCCAGGGGTATGGCAGG
TTTATGACAAGAGCGATTATTTAGAAGAACAGCGTAAAGCTTACCAGGCATGGTGGGAGAGAGTTGAATCGATCGTTACT
TGTACTGGTTCAGACAGCAACTGA

Upstream 100 bases:

>100_bases
CTTTAAATCGATCAGCTTGCTTTCATCAAAAATCTGTACATATGCTTGTACATAATGTACAAAGCAGCAGAGGTGTTTTG
CGATTTGTACAAGGTGAGTA

Downstream 100 bases:

>100_bases
CAGTCCGCTTTGAGCAAGAAGCGGAAGTTGGCAGTTTTGTGGACTGTCCCCACAAAAGTGACTACAGAAATAGTTGCAAT
TCATAATTGATCATGGGTTG

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRYQWAGKGERLDIGTYPATGLKEAREEVIRLRGELESN
RNPRLVKQAEKRKATEAMTVESVIRAWYEAYCVKNKKGSEQILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPA
IADRLLINAKQAHVWAYKRKLIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAIDGSRMVPKYRAFIKLLLHFGCR
SSELITARVDDFDFINKVWTVPPERHKTGDITGEPLKRPIIEPVEELIKYVISMNNGSDMLFTKEGCREPVGRTSLQSLP
YNLMQYAWRRLGYQFPHWSLHDLRRTARTNFSDLTAPHIAEIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWWERVESIVT
CTGSDSN

Sequences:

>Translated_407_residues
MALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRYQWAGKGERLDIGTYPATGLKEAREEVIRLRGELESN
RNPRLVKQAEKRKATEAMTVESVIRAWYEAYCVKNKKGSEQILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPA
IADRLLINAKQAHVWAYKRKLIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAIDGSRMVPKYRAFIKLLLHFGCR
SSELITARVDDFDFINKVWTVPPERHKTGDITGEPLKRPIIEPVEELIKYVISMNNGSDMLFTKEGCREPVGRTSLQSLP
YNLMQYAWRRLGYQFPHWSLHDLRRTARTNFSDLTAPHIAEIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWWERVESIVT
CTGSDSN
>Mature_406_residues
ALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRYQWAGKGERLDIGTYPATGLKEAREEVIRLRGELESNR
NPRLVKQAEKRKATEAMTVESVIRAWYEAYCVKNKKGSEQILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPAI
ADRLLINAKQAHVWAYKRKLIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAIDGSRMVPKYRAFIKLLLHFGCRS
SELITARVDDFDFINKVWTVPPERHKTGDITGEPLKRPIIEPVEELIKYVISMNNGSDMLFTKEGCREPVGRTSLQSLPY
NLMQYAWRRLGYQFPHWSLHDLRRTARTNFSDLTAPHIAEIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWWERVESIVTC
TGSDSN

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=395, Percent_Identity=25.5696202531646, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788974, Length=409, Percent_Identity=24.9388753056235, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 47085; Mature: 46954

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRYQWAGKGERLDIGTYPA
CCCCHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCEEEEEEEEECCCCCEEECCCCCC
TGLKEAREEVIRLRGELESNRNPRLVKQAEKRKATEAMTVESVIRAWYEAYCVKNKKGSE
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPAIADRLLINAKQAHVWAYKRK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAIDGSRMVPKYRAFIKLLLHFGCR
HHHCCCCCCCCCCCCHHCCCCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
SSELITARVDDFDFINKVWTVPPERHKTGDITGEPLKRPIIEPVEELIKYVISMNNGSDM
CCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCE
LFTKEGCREPVGRTSLQSLPYNLMQYAWRRLGYQFPHWSLHDLRRTARTNFSDLTAPHIA
EEEHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHCCHHHHH
EIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWWERVESIVTCTGSDSN
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure 
ALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRYQWAGKGERLDIGTYPA
CCCHHHHHHHHCCCCCCEEEECCCCCCEEEECCCCCEEEEEEEEECCCCCEEECCCCCC
TGLKEAREEVIRLRGELESNRNPRLVKQAEKRKATEAMTVESVIRAWYEAYCVKNKKGSE
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPAIADRLLINAKQAHVWAYKRK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAIDGSRMVPKYRAFIKLLLHFGCR
HHHCCCCCCCCCCCCHHCCCCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCC
SSELITARVDDFDFINKVWTVPPERHKTGDITGEPLKRPIIEPVEELIKYVISMNNGSDM
CCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHCCCCCCE
LFTKEGCREPVGRTSLQSLPYNLMQYAWRRLGYQFPHWSLHDLRRTARTNFSDLTAPHIA
EEEHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHCCHHHHH
EIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWWERVESIVTCTGSDSN
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]