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The map label for this gene is argE [H]

Identifier: 218551052

GI number: 218551052

Start: 3895813

End: 3896964

Strand: Direct

Name: argE [H]

Synonym: EFER_3806

Alternate gene names: 218551052

Gene position: 3895813-3896964 (Clockwise)

Preceding gene: 218551047

Following gene: 218551053

Centisome position: 84.9

GC content: 51.04

Gene sequence:

>1152_bases
ATGAAAAACAAATTACCGCCATTTATCGAGATTTACCGCGCTCTGATTGCCACACCATCGATTAGCGCAACGGAAGAAGC
GCTCGATCAAAGTAATGCGGGTTTAATCACTCTACTGGCGGACTGGTTTAAAGATCTGGGCTTCAATGTGGAAGTACAGC
CAGTACCCGGCACACGTAACAAATTCAATATGCTGGCAAGTACCGGACAAGGCGCAGGCGGCTTGCTGCTGGCCGGTCAT
ACCGATACCGTGCCATTTGATGATGGGCGTTGGACGCGCGATCCATTCACCCTGACCGAGCATGACGGCAAGCTCTATGG
TCTGGGTACGGCTGATATGAAAGGTTTCTTTGCGTTTATTCTTGATACGCTACGCGACGTTGACGTTACGAAACTGAAAA
AGCCGCTCTATATTCTGGCGACCGCCGACGAAGAAACCAGTATGGCGGGTGCACGTTACTTCTCGGAAACCACCTCCCTG
CGTCCGGATTGTGCCATTATCGGCGAGCCAACATCACTGCAACCTGTTCGAGCGCATAAAGGTCATATCTCCAACACGAT
TCGAGTAATGGGGCAGTCGGGGCACTCCAGTGATCCTGCTCGTGGTGTAAATGCTATTGAACTGATGCATGATGCCATCG
GTCATATCCTGCAACTGCGTGACACTCTTAAAGAACGCTATCACTATGAGGCATTTACCGTGCCTTACCCCACGCTTAAC
CTTGGTCATATTCACGGCGGCGACGCAGCTAACCGTATCTGCGCTTGCTGTGAGTTGCATATGGATATTCGCCCTTTACC
GGGAATGACGCTCAACGATCTCAATGGGTTACTCAACGAAGCGCTGGCTCCAGTGAGTGAACGCTGGCCGGGTCGCCTGA
CGGTAGAAGAGTTGCATCCTCCTATTCCGGGTTATGAATGCCCGCCGGACCACCAACTGGTTGAAGTGGTTGAGAAATTA
CTCGGCACACATACCGAAGTAGTGAATTACTGTACCGAAGCGCCTTTTATTCAAACGTTATGTCCGACGCTGGTGTTAGG
ACCGGGTTCAATCAACCAGGCCCATCAGCCTGATGAATATCTGGAGACGCGTTTTATCAAGCCGACCCGTGAGCTGATCA
CTCAGGTTATTCACCATTTCTGCTGGCATTAA

Upstream 100 bases:

>100_bases
CCTTACGGCTGGTGGGTTTTATTACGCTCAACGTTAGTGTATTTTTATTCACAAATAATGCATGAATATTGATACTATCA
TGACCTGAGGTGTGTCAACA

Downstream 100 bases:

>100_bases
AAAAACGAGTGATGCCCAATTGTAGTCGGATAAGGCGGTCCAGCCGCAGTAATGTCGGATAAGATGTTGACGCATCTTAT
CCGACCTACTGTCATTCATA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSL
RPDCAIIGEPTSLQPVRAHKGHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLN
LGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHPPIPGYECPPDHQLVEVVEKL
LGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Sequences:

>Translated_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSL
RPDCAIIGEPTSLQPVRAHKGHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLN
LGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHPPIPGYECPPDHQLVEVVEKL
LGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
>Mature_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSL
RPDCAIIGEPTSLQPVRAHKGHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLN
LGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHPPIPGYECPPDHQLVEVVEKL
LGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=383, Percent_Identity=95.822454308094, Blast_Score=768, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=373, Percent_Identity=25.7372654155496, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788816, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=391, Percent_Identity=24.5524296675192, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42384; Mature: 42384

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCH
KFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSLRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHC
GHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLN
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
LGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHHCC
PIPGYECPPDHQLVEVVEKLLGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCH
KFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSLRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHC
GHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLN
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
LGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHP
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHHCC
PIPGYECPPDHQLVEVVEKLLGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA