Click here to switch to the map view.

The map label for this gene is yifK [H]

Identifier: 218550980

GI number: 218550980

Start: 3801483

End: 3802868

Strand: Reverse

Name: yifK [H]

Synonym: EFER_3708

Alternate gene names: 218550980

Gene position: 3802868-3801483 (Counterclockwise)

Preceding gene: 218550981

Following gene: 218550979

Centisome position: 82.87

GC content: 52.38

Gene sequence:

>1386_bases
ATGGCAGATAACAAACCAGAGCTACAGCGTGGGCTGGAAGCTCGACATATCGAACTCATCGCCCTGGGGGGCACCATTGG
CGTCGGCCTGTTTATGGGGGCCGCCAGTACCCTGAAATGGGCCGGGCCATCCGTATTGTTGGCCTATATCATCGCCGGGC
TGTTCGTCTTTTTCATCATGCGTTCAATGGGCGAAATGTTGTTCCTCGAACCGGTTACCGGTTCGTTCGCCGTTTATGCG
CATCGTTATATGAGCCCGTTTTTTGGCTATCTCACCGCCTGGTCTTACTGGTTTATGTGGATGGCGGTGGGGATCTCAGA
AATCACCGCCATTGGCGTTTATGTCCAGTTCTGGTTCCCGGAGATGGCGCAGTGGATACCCGCATTGATCGCGGTGGCGC
TGGTAGCGTTGGCGAATCTGGCGGCAGTGCGGTTGTACGGCGAAATCGAATTCTGGTTCGCGATGATCAAAGTCACCACG
ATTATCGTGATGATTGTCATTGGCCTGGGCGTAATTTTCTTTGGTTTTGGCAATGGCGGGCAGTCGATTGGTTTTAGCAA
TCTCACAGAGCATGGCGGTTTCTTTGCGGGTGGCTGGAAAGGGTTCCTGACCGCATTGTGTATTGTGGTGGCGTCCTACC
AGGGCGTGGAGCTGATTGGCATTACGGCCGGTGAAGCGAAGAATCCGCAGGTGACACTGCGTAGTGCCGTTGGCAAAGTG
CTGTGGCGAATCCTGATTTTCTACGTAGGTGCGATTTTCGTTATTGTCACCATCTTCCCGTGGAATGAAATTGGCAGCAA
CGGCAGCCCGTTCGTACTGACTTTCGCCAAAATCGGCATTACCGCAGCGGCGGGTATTATCAACTTTGTGGTGCTGACGG
CTGCGCTCTCTGGCTGTAACAGCGGCATGTACAGTTGCGGACGTATGCTCTACGCGCTGGCGAAAAACCGTCAGTTACCG
GCGGCGATGGCGAAAGTTTCCCGTCAAGGTGTTCCGGTTGCAGGCGTGGCGGTATCAATTGCTATTCTGTTAATTGGCTC
ATGCCTGAACTATATCATTCCCAATCCACAGCGTGTGTTTGTCTATGTCTACAGTGCCAGCGTGCTTCCGGGGATGGTGC
CATGGTTTGTGATTTTGATAAGCCAGTTGCGTTTTCGTCGAGCGCACAAAGCGGCGATTGCCAGCCATCCGTTCCGCTCA
ATCCTGTTCCCGTGGGCCAACTACGTAACAATGGCATTCCTGATTTGCGTTTTGATCGGCATGTACTTTAATGAAGATAC
GCGTATGTCACTGTTTGTCGGCATCATCTTTATGCTGGCGGTGACGGCAATTTATAAAGTTTTTGGACTTAATCGCCACG
GTAAAGCGCATAAGCTGGATGAATAA

Upstream 100 bases:

>100_bases
TTGCCATTTCTCCTGAATTACGAAAACATTCGCAACACTCGATGTACCCATAACGATAACCGGTAACACCGGAAAGCATG
CAAACACAACACGAGGATTT

Downstream 100 bases:

>100_bases
TCGGCAAAACGCACAAACCGTAACCAAACGCGCAATTTATTTAAAAAGGGACTAGACAGAGGGGTGGGAAGTCCGTATTA
TCCACCCCCGCAACGGCGCT

Product: transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRQGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLDE

Sequences:

>Translated_461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRQGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLDE
>Mature_460_residues
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH
RYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTI
IVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL
WRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA
AMAKVSRQGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSI
LFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLDE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=99.5661605206074, Blast_Score=916, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=44.0559440559441, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=431, Percent_Identity=40.1392111368909, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=44.7826086956522, Blast_Score=338, Evalue=5e-94,
Organism=Escherichia coli, GI1790653, Length=462, Percent_Identity=38.5281385281385, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI87081915, Length=392, Percent_Identity=39.5408163265306, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI1788480, Length=435, Percent_Identity=39.0804597701149, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI87081708, Length=471, Percent_Identity=36.7303609341826, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1789017, Length=464, Percent_Identity=32.7586206896552, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI2367353, Length=460, Percent_Identity=25.4347826086956, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324061, Length=438, Percent_Identity=35.3881278538813, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6320772, Length=437, Percent_Identity=33.8672768878719, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324924, Length=414, Percent_Identity=32.3671497584541, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324990, Length=447, Percent_Identity=30.4250559284116, Blast_Score=192, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6322892, Length=437, Percent_Identity=30.8924485125858, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=439, Percent_Identity=33.0296127562642, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322967, Length=415, Percent_Identity=30.3614457831325, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321629, Length=404, Percent_Identity=27.970297029703, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=29.2161520190024, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6319824, Length=436, Percent_Identity=28.4403669724771, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6319608, Length=422, Percent_Identity=28.6729857819905, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324981, Length=410, Percent_Identity=30.4878048780488, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319543, Length=400, Percent_Identity=29.25, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=30.9823677581864, Blast_Score=156, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6319542, Length=403, Percent_Identity=27.2952853598015, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320717, Length=404, Percent_Identity=25.7425742574257, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=400, Percent_Identity=26.5, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=555, Percent_Identity=23.963963963964, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI221512776, Length=360, Percent_Identity=21.9444444444444, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666159, Length=360, Percent_Identity=21.9444444444444, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50377; Mature: 50246

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRQGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLDE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRQGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLDE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]