Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 218550960

GI number: 218550960

Start: 3777397

End: 3778347

Strand: Reverse

Name: corA [H]

Synonym: EFER_3686

Alternate gene names: 218550960

Gene position: 3778347-3777397 (Counterclockwise)

Preceding gene: 218550963

Following gene: 218550958

Centisome position: 82.34

GC content: 52.26

Gene sequence:

>951_bases
ATGCTGAGCGCATTTCAACTGGAAAATAACCGACTGACCCGGCTGGAAGTCGAAGAGTCACAACCCCTTGTAAATGCAGT
ATGGATTGATCTTGTCGAACCGGATGACGACGAGCGACTGCGCGTACAATCTGAACTTGGCCAGAGCCTGGCAACCCGCC
CGGAACTGGAAGATATCGAAGCATCGGCACGTTTCTTTGAAGACGATGACGGCCTGCATATTCACTCCTTCTTCTTCTTT
GAAGATGCGGAAGATCACGCCGGTAACTCCACTGTGGCATTTACCATCCGTGATGGTCGTCTGTTTACTCTGCGTGAGCG
TGAACTGCCTGCATTCCGTCTGTATCGTATGCGCGCCCGTAGCCAGTCAATGGTGGACGGTAACGCCTACGAGCTGCTGT
TGGATCTGTTCGAAACCAAAATCGAACAGCTGGCAGATGAAATTGAAAATATCTATAGCGACCTGGAGCAGTTGAGCCGG
GTAATTATGGAAGGGCATCAGGGCGATGAGTACGACGAGGCGCTCTCCACACTGGCGGAGCTGGAAGATATCGGCTGGAA
AGTTCGCCTGTGTCTGATGGATACCCAGCGTGCACTCAACTTCCTGGTGCGTAAAGCACGCTTACCGGGTGGGCAACTGG
AGCAGGCGCGTGAAATCCTGCGAGATATCGAATCCCTGCTGCCGCATAACGAATCCCTGTTCCAGAAGGTGAACTTCCTG
ATGCAGGCGGCTATGGGCTTTATCAACATCGAGCAGAACCGCATCATCAAAATCTTCTCGGTGGTATCCGTCGTGTTCCT
GCCGCCGACGCTGGTTGCTTCCAGCTATGGCATGAACTTTGAGTTTATGCCAGAGTTGAAGTGGAGTTTCGGCTACCCGG
CAGCGATTATCTTTATGATCCTCGCAGGCCTGGCACCGTATCTGTACTTTAAACGGAAGAACTGGTTGTAA

Upstream 100 bases:

>100_bases
TCCCGTCGCGCTGAGTCAGGCTGTTTAATGGTCTGAAACCCAATTTGTTTCTGTGTGCCCACCGAACTGTCCGATATTTT
AAGCATTGGGAGTCCCGGTC

Downstream 100 bases:

>100_bases
AAAACGAGAGTGGTGGTTTAGCCCGGCTAAGCCACCAGTTATTCAAAGGCTCCAGGTATTTAACCCTTTTACCTCTTTCT
CATAAAACCATTTGTTCGTG

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFF
EDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPAAIIFMILAGLAPYLYFKRKNWL

Sequences:

>Translated_316_residues
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFF
EDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPAAIIFMILAGLAPYLYFKRKNWL
>Mature_316_residues
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFF
EDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPAAIIFMILAGLAPYLYFKRKNWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=316, Percent_Identity=99.6835443037975, Blast_Score=641, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36604; Mature: 36604

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIE
CCCCEEECCCCEEEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
ASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRAR
HHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHH
SQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSRVIMEGHQGDEYDEALSTLAE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
HHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPAAIIFMI
HHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHH
LAGLAPYLYFKRKNWL
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIE
CCCCEEECCCCEEEEEECCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHH
ASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRAR
HHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHH
SQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSRVIMEGHQGDEYDEALSTLAE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
HHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPAAIIFMI
HHHHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHH
LAGLAPYLYFKRKNWL
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]