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The map label for this gene is yurK [H]

Identifier: 218550931

GI number: 218550931

Start: 3745084

End: 3745848

Strand: Reverse

Name: yurK [H]

Synonym: EFER_3657

Alternate gene names: 218550931

Gene position: 3745848-3745084 (Counterclockwise)

Preceding gene: 218550935

Following gene: 218550929

Centisome position: 81.63

GC content: 46.41

Gene sequence:

>765_bases
TTGACTATACAACTTATCGAAAAGAGAATTTTGTACATGGCTCACACTTTGCCGCTTTATGTTCAGATTCAGGAACAACT
GCGTAGTGATATAAAAACCGGAGAGTTTAAACCGGGGGAAAAGCTACCGTCTGAAAACGAACTGGCCCAACAGTATTCAA
CGACTCGGGCGACAGTAGTTCATGCCATGCAAGGGTTACTGGTAGAGGGGCTAATTGAGCGTATTCGTGGGAAAGGAACG
TTTGTTAAGGCCTCACCTATCATTTCCAGGGTCAGCACACAGGAGATTGGTTTCTTCGAAAAAGATCTCCAGGATGCCGA
CTTATCCGTGCGGTACAAAGTACTGCAATTTAATGAATGTGCTTCTTCTGCGGAACTACAGGCGCATTTGAAAGCTGAAC
CGCAAGATAAAATATACCGCCTTATGCGTTTACGTCTTGTGCAGGACAAACCTTTAGCGCTTGAAATTCGCTATCTGAAA
GGTGATATCGCGCGTAAATTGCAGCTGGAAGGTCTGGAGATGCTGCCATTACAGGTGCTTTTTGAACAACAACTTGGGGT
AGTAATCCATACGATTCACAATCAGATCCGTGTGGCACTACCGGGGCAAGAAATCGCTCAGACACTGGAATGCAAACGAA
CGCGCCCGATGATGGTGCGCCAGCATACCTGCCTGACGGGTAATGATGCTCCTGTTCTCTGGGGCGAAACCTGGTACCGT
GAGGAGTATGAATTTCAATACAGTACCTATCGTAAGCAGGAATAA

Upstream 100 bases:

>100_bases
TTTTCAGCACGATAGCGATAAACTATCAGCAAAACGTAATCCAATTTTCACGTAGAAACGTTCAAATCATACATAGTTGT
ATAGTCAACTTTAACTGTAG

Downstream 100 bases:

>100_bases
CCTGCCGTAATTAACGGCAGGCAGGCGTGCAAAACTTCTCACCGGATGCGGCGTAATAAGTTTCGTATAGGGCAATTCTG
TACTTGTTATCTAACTGATC

Product: GntR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTIQLIEKRILYMAHTLPLYVQIQEQLRSDIKTGEFKPGEKLPSENELAQQYSTTRATVVHAMQGLLVEGLIERIRGKGT
FVKASPIISRVSTQEIGFFEKDLQDADLSVRYKVLQFNECASSAELQAHLKAEPQDKIYRLMRLRLVQDKPLALEIRYLK
GDIARKLQLEGLEMLPLQVLFEQQLGVVIHTIHNQIRVALPGQEIAQTLECKRTRPMMVRQHTCLTGNDAPVLWGETWYR
EEYEFQYSTYRKQE

Sequences:

>Translated_254_residues
MTIQLIEKRILYMAHTLPLYVQIQEQLRSDIKTGEFKPGEKLPSENELAQQYSTTRATVVHAMQGLLVEGLIERIRGKGT
FVKASPIISRVSTQEIGFFEKDLQDADLSVRYKVLQFNECASSAELQAHLKAEPQDKIYRLMRLRLVQDKPLALEIRYLK
GDIARKLQLEGLEMLPLQVLFEQQLGVVIHTIHNQIRVALPGQEIAQTLECKRTRPMMVRQHTCLTGNDAPVLWGETWYR
EEYEFQYSTYRKQE
>Mature_253_residues
TIQLIEKRILYMAHTLPLYVQIQEQLRSDIKTGEFKPGEKLPSENELAQQYSTTRATVVHAMQGLLVEGLIERIRGKGTF
VKASPIISRVSTQEIGFFEKDLQDADLSVRYKVLQFNECASSAELQAHLKAEPQDKIYRLMRLRLVQDKPLALEIRYLKG
DIARKLQLEGLEMLPLQVLFEQQLGVVIHTIHNQIRVALPGQEIAQTLECKRTRPMMVRQHTCLTGNDAPVLWGETWYRE
EYEFQYSTYRKQE

Specific function: Possible Transcriptional Regulator Of The Succinyl-CoA- Synthetase Operon. Binds Specifically To The Farr Promoter And Exhibits Weak Binding To The Citrate Synthase And Lipoamide Dehydrogenase Promoters. Binding At The Farr Promoter Is Abolished By Long-

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=206, Percent_Identity=29.126213592233, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790118, Length=228, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082252, Length=229, Percent_Identity=24.4541484716157, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788418, Length=245, Percent_Identity=22.8571428571429, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29459; Mature: 29327

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQLIEKRILYMAHTLPLYVQIQEQLRSDIKTGEFKPGEKLPSENELAQQYSTTRATVV
CCHHHHHHHHHHHHHHCHHHEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HAMQGLLVEGLIERIRGKGTFVKASPIISRVSTQEIGFFEKDLQDADLSVRYKVLQFNEC
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEHHH
ASSAELQAHLKAEPQDKIYRLMRLRLVQDKPLALEIRYLKGDIARKLQLEGLEMLPLQVL
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHH
FEQQLGVVIHTIHNQIRVALPGQEIAQTLECKRTRPMMVRQHTCLTGNDAPVLWGETWYR
HHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCCCEECCCEECCCCCCEEECCHHHC
EEYEFQYSTYRKQE
HHHHHHHHHHCCCC
>Mature Secondary Structure 
TIQLIEKRILYMAHTLPLYVQIQEQLRSDIKTGEFKPGEKLPSENELAQQYSTTRATVV
CHHHHHHHHHHHHHHCHHHEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
HAMQGLLVEGLIERIRGKGTFVKASPIISRVSTQEIGFFEKDLQDADLSVRYKVLQFNEC
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEEHHH
ASSAELQAHLKAEPQDKIYRLMRLRLVQDKPLALEIRYLKGDIARKLQLEGLEMLPLQVL
CCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHHH
FEQQLGVVIHTIHNQIRVALPGQEIAQTLECKRTRPMMVRQHTCLTGNDAPVLWGETWYR
HHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCCCEECCCEECCCCCCEEECCHHHC
EEYEFQYSTYRKQE
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]