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The map label for this gene is mtlR [H]

Identifier: 218550876

GI number: 218550876

Start: 3678459

End: 3679004

Strand: Direct

Name: mtlR [H]

Synonym: EFER_3592

Alternate gene names: 218550876

Gene position: 3678459-3679004 (Clockwise)

Preceding gene: 218550875

Following gene: 218550878

Centisome position: 80.16

GC content: 51.83

Gene sequence:

>546_bases
TTGTCAGATATGCAGGCAACAATGGAACAAACCCAGGCCTTTGAAAACCGTGTGCTGGAGCGTCTGAATGCTGGCAAAAC
CGTACGGAGCTTTTTGATCACCGCTGTCGATCTCCTGACCGACGCGGTGAATATTCTGGTGCTCCAGGTCTTCCGTAAAG
ACGACTACGCGGTGAAATACGCAGTTGAACCGTTGCTTGACGGCGACGGTCCGCTGGGCGATCTCTCCGTCCGCCTGAAA
CTTATCTATGGGCTTGGCGTAATTAGCCGCCATGAATATGAAGATGCAGAGTTGCTGATGGCGTTACGTGAAGAGTTAAA
TCATGACGGCAACGAATACGCGTTTACCGATGACGAGATTCTGGGGCCATTTGGCGAGCTACACTGTGTGGCGGCACTGC
CGCCGCCACCGCAGTTTGAGCTTTCTGATCCCAGCCTGTACGCAATGCAGATTCAGCGCTATCAACAGGCGGTACGTTCA
ACGATGGTGCTTTCCCTGACCGAGCTGATTTCAACAATCAGCTTGAAAAAAGCCTTTCAGAAGTAA

Upstream 100 bases:

>100_bases
TGATGCTAACAGCGATGTCGTCATTGAGGCGGTACGCGTTTATAACGAAAAGCAATGATGTAAGACCAGGCCGCAGGGTA
ACCTGCGCCTGAAACATAGA

Downstream 100 bases:

>100_bases
ACAAACTCCCGCTTACAGTTTCTCTTCCTGTTTTGGTCGATAGAGCTGTCGATAATAATCCAGGCGTTGTAGATACACCT
GCGCGTTTTCCTTCGGTACG

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVDLLTDAVNILVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLK
LIYGLGVISRHEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFELSDPSLYAMQIQRYQQAVRS
TMVLSLTELISTISLKKAFQK

Sequences:

>Translated_181_residues
MSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVDLLTDAVNILVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLK
LIYGLGVISRHEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFELSDPSLYAMQIQRYQQAVRS
TMVLSLTELISTISLKKAFQK
>Mature_180_residues
SDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVDLLTDAVNILVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKL
IYGLGVISRHEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFELSDPSLYAMQIQRYQQAVRST
MVLSLTELISTISLKKAFQK

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=181, Percent_Identity=94.475138121547, Blast_Score=351, Evalue=2e-98,
Organism=Escherichia coli, GI1789297, Length=105, Percent_Identity=36.1904761904762, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 20338; Mature: 20206

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVDLLTDAVNILVLQVFRKDDYAVKY
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AVEPLLDGDGPLGDLSVRLKLIYGLGVISRHEYEDAELLMALREELNHDGNEYAFTDDEI
EHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHH
LGPFGELHCVAALPPPPQFELSDPSLYAMQIQRYQQAVRSTMVLSLTELISTISLKKAFQ
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure 
SDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVDLLTDAVNILVLQVFRKDDYAVKY
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AVEPLLDGDGPLGDLSVRLKLIYGLGVISRHEYEDAELLMALREELNHDGNEYAFTDDEI
EHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHH
LGPFGELHCVAALPPPPQFELSDPSLYAMQIQRYQQAVRSTMVLSLTELISTISLKKAFQ
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]