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The map label for this gene is yibH [H]

Identifier: 218550871

GI number: 218550871

Start: 3673220

End: 3674356

Strand: Reverse

Name: yibH [H]

Synonym: EFER_3587

Alternate gene names: 218550871

Gene position: 3674356-3673220 (Counterclockwise)

Preceding gene: 218550872

Following gene: 218550870

Centisome position: 80.07

GC content: 51.01

Gene sequence:

>1137_bases
ATGGATCTATTGATTGTTTTAACTTACGTGGCGCTGGCGTGGGCGGTCTTTAAAATCTTCCGCATTCCGGTGAATCAGTG
GACGCTGGCGACCGCGGCGCTCGGCGGTGTGTTTCTGGTGAGTGGTTTAATTTTATTAATGAACTACAACCATCCTTACA
CCTTTACGGCACAAAAAGCGGTGATTTCAATTCCGATTACGCCGCAGGTAACGGGGATCGTCAGCGAAGTCACTGACAAA
AATAATCAACTTATTCACAAGGGAGACGTGCTCTTTAAGCTTGATCCGGTGCGTTATCAGGCGCGAGTGACACGGCTTCA
GGCTGACCTGATGACAGCAACCCACAACATCAAAACGCTAAGGGCACAATTAGCGGAAGCCGTGGCGAACACGACGCAGG
TATCAGCAGAGCGCGATCGTCTGTATAAAAATTATCAGCGTTACCTGAAAGGTAGTCAGGCGGTGGTTAATCCTTTTTCA
GAACGAGATATTGACGATGCCCGACAAAACTTTCTTGCTCAGGATGCCCTGGTGAAAGGTTCGGTGGCGGAACAGGCACA
AATTCAAAGTCAGTTAGACAGCATGATCAATGGTGAGCAATCGCAAATTGTCAGCTTAAGAGCACAGCTGGCGGAGGCGG
AATATAACCTGGCGCAAACTGTTGTGCGGGCGCCGAGCAATGGCTACGTCACCCAGGTACTGATTCGCCCTGGTACTTAC
GCGGCTGCATTACCCCTACGCCCGGTGATGGTGTTTATCCCTGAACAGAAACGGCAAATTGTCGCTCAGTTCCGGCAAAA
CTCGCTGCTGCGTCTGGAGTCTGGCGATGAAGCCGAAGTGGTGTTCAATGCGCTGCCAGGGCAAGTCTTTCGTGGCAAGT
TGACGCAAATTCTGCCCGTTGTTCCTGGCGGCTCGTATCAGGCGCAAGGGGTATTGCAATCGCTGACGGTCGTGCCAGGA
ACAGACGGCGTACTTGCGCTGATTGATCTGGAACCTAATGCTGAGGTTGATGCTCTGCCCGACGGCATTTACGCCCAGGT
TGCGGTTTATTCAGACCATTTCAGCCACGTTTCCGTTATGCGCAAAGTACTCCTGCGTATGACCAGTTGGATGCACTATC
TTTATTTAGATCATTGA

Upstream 100 bases:

>100_bases
ACCCGGAAATCGCCGCACTTTCGGCGCGAATTTCCCGGCTGGAGCAGCAGCTCGCCACTGACAAAAAACCTGATTACTCC
ACGTTCCCGGAGATCTAACT

Downstream 100 bases:

>100_bases
TATTTTATTGGCTGCCTTTTTTTTAACCCTGAGTCATACTCATATTTTGTTAACAAAAAGGAAACATAATGAAGCTCATC
GGTAGTTACACCAGTCCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKAVISIPITPQVTGIVSEVTDK
NNQLIHKGDVLFKLDPVRYQARVTRLQADLMTATHNIKTLRAQLAEAVANTTQVSAERDRLYKNYQRYLKGSQAVVNPFS
ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMINGEQSQIVSLRAQLAEAEYNLAQTVVRAPSNGYVTQVLIRPGTY
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLESGDEAEVVFNALPGQVFRGKLTQILPVVPGGSYQAQGVLQSLTVVPG
TDGVLALIDLEPNAEVDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH

Sequences:

>Translated_378_residues
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKAVISIPITPQVTGIVSEVTDK
NNQLIHKGDVLFKLDPVRYQARVTRLQADLMTATHNIKTLRAQLAEAVANTTQVSAERDRLYKNYQRYLKGSQAVVNPFS
ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMINGEQSQIVSLRAQLAEAEYNLAQTVVRAPSNGYVTQVLIRPGTY
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLESGDEAEVVFNALPGQVFRGKLTQILPVVPGGSYQAQGVLQSLTVVPG
TDGVLALIDLEPNAEVDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH
>Mature_378_residues
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKAVISIPITPQVTGIVSEVTDK
NNQLIHKGDVLFKLDPVRYQARVTRLQADLMTATHNIKTLRAQLAEAVANTTQVSAERDRLYKNYQRYLKGSQAVVNPFS
ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMINGEQSQIVSLRAQLAEAEYNLAQTVVRAPSNGYVTQVLIRPGTY
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLESGDEAEVVFNALPGQVFRGKLTQILPVVPGGSYQAQGVLQSLTVVPG
TDGVLALIDLEPNAEVDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=378, Percent_Identity=93.1216931216931, Blast_Score=724, Evalue=0.0,
Organism=Escherichia coli, GI1790012, Length=378, Percent_Identity=75.3968253968254, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1790519, Length=253, Percent_Identity=26.8774703557312, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081951, Length=290, Percent_Identity=23.7931034482759, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41917; Mature: 41917

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKA
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCE
VISIPITPQVTGIVSEVTDKNNQLIHKGDVLFKLDPVRYQARVTRLQADLMTATHNIKTL
EEEECCCCCHHHHHHHHCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RAQLAEAVANTTQVSAERDRLYKNYQRYLKGSQAVVNPFSERDIDDARQNFLAQDALVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCC
SVAEQAQIQSQLDSMINGEQSQIVSLRAQLAEAEYNLAQTVVRAPSNGYVTQVLIRPGTY
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLESGDEAEVVFNALPGQVFRGKLTQILPV
EEECCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCHHEEEECCCCHHHHCCHHHHEEC
VPGGSYQAQGVLQSLTVVPGTDGVLALIDLEPNAEVDALPDGIYAQVAVYSDHFSHVSVM
CCCCCCHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
RKVLLRMTSWMHYLYLDH
HHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKA
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCE
VISIPITPQVTGIVSEVTDKNNQLIHKGDVLFKLDPVRYQARVTRLQADLMTATHNIKTL
EEEECCCCCHHHHHHHHCCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RAQLAEAVANTTQVSAERDRLYKNYQRYLKGSQAVVNPFSERDIDDARQNFLAQDALVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCC
SVAEQAQIQSQLDSMINGEQSQIVSLRAQLAEAEYNLAQTVVRAPSNGYVTQVLIRPGTY
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCE
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLESGDEAEVVFNALPGQVFRGKLTQILPV
EEECCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCCHHEEEECCCCHHHHCCHHHHEEC
VPGGSYQAQGVLQSLTVVPGTDGVLALIDLEPNAEVDALPDGIYAQVAVYSDHFSHVSVM
CCCCCCHHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
RKVLLRMTSWMHYLYLDH
HHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]