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The map label for this gene is sgbH [H]

Identifier: 218550863

GI number: 218550863

Start: 3663879

End: 3664541

Strand: Direct

Name: sgbH [H]

Synonym: EFER_3579

Alternate gene names: 218550863

Gene position: 3663879-3664541 (Clockwise)

Preceding gene: 218550862

Following gene: 218550864

Centisome position: 79.85

GC content: 58.82

Gene sequence:

>663_bases
ATGAGCAGACCACTTCTGCAACTGGCCCTCGACCACTCATCACTTGAAGCCGCACAGCGCGACGTTGCGCTGTTAAAAGA
CAGCGTCGATATCGTCGAAGCGGGCACCATTCTCTGTTTAAACGAAGGGCTTGGCGCGGTGAAAGCCTTGCGCGAACAGT
GCCCGGACAAAATCATCGTTGCTGACTGGAAGGTCGCCGATGCTGGTGAAACGCTCGCGCAACAGGCGTTTGGCGCAGGC
GCTAACTGGATGACCATCATCTGCGCTGCGCCGCTCGCGACGGTAGAAAAAGGCCACGCAATGGCGCAAAGCTGCGGTGG
TGAAATCCAGATAGAGCTTTTTGGTAACTGGACGCTGGACGACGCCCGCGACTGGCATCGTATTGGCGTGCGGCAGGCCA
TTTATCATCGTGGCCGTGACGCGCAAGCCAGCGGGCAACAGTGGGGCGAAGCCGATCTGGCACGCATGAAGGCGCTTTCC
GATATCGGCCTTGAGCTTTCCGTTACCGGCGGGATTACGCCTGCTGACCTGCCGCTGTTTAAAGATATCCGCGTGAAGGC
ATTTATTGCCGGACGAGCACTGGCAGGCGCAGCAAATCCGGCACAGGTAGCTGCCGACTTCCATGCGCAAATCGACGCTA
TCTGGGGAGGCGCGCGTGCGTAA

Upstream 100 bases:

>100_bases
ATATGACCGCCCATCAGCTTTACCAACAAAAATACCAACGCTATCAGCACCTCATTGCCGCACTACAGGGCTTTCATGCC
CGCGTTAAGGAGAACACATT

Downstream 100 bases:

>100_bases
TCATCCGTTAGGGATTTATGAAAAAGCGCTGGCGAAAGATCTCTCCTGGCCGGAGCGGCTGGTGCTGGCAAAAAGCTGCG
GTTTTGATTTTGTCGAAATG

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSRPLLQLALDHSSLEAAQRDVALLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAMAQSCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
DIGLELSVTGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAADFHAQIDAIWGGARA

Sequences:

>Translated_220_residues
MSRPLLQLALDHSSLEAAQRDVALLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAG
ANWMTIICAAPLATVEKGHAMAQSCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
DIGLELSVTGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAADFHAQIDAIWGGARA
>Mature_219_residues
SRPLLQLALDHSSLEAAQRDVALLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGA
NWMTIICAAPLATVEKGHAMAQSCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSD
IGLELSVTGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAADFHAQIDAIWGGARA

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=220, Percent_Identity=98.1818181818182, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1790640, Length=216, Percent_Identity=46.2962962962963, Blast_Score=210, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23346; Mature: 23215

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLLQLALDHSSLEAAQRDVALLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIV
CCCCHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMAQSCGGEIQIELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
DARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSDIGLELSVTGGITPADLPLF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHH
KDIRVKAFIAGRALAGAANPAQVAADFHAQIDAIWGGARA
HHCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRPLLQLALDHSSLEAAQRDVALLKDSVDIVEAGTILCLNEGLGAVKALREQCPDKIIV
CCCHHHHHHCCHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCHHHHHHHHHCCCCEEE
ADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMAQSCGGEIQIELFGNWTLD
ECCEECCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
DARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALSDIGLELSVTGGITPADLPLF
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCHH
KDIRVKAFIAGRALAGAANPAQVAADFHAQIDAIWGGARA
HHCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 9274005; 11741871 [H]